Chapter 15 Flashcards

1
Q

What is a pathologic cavity lined by odontogenic epithelium and filled with fluid or semisolid material?

A
  • Odontogenic Cyst
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2
Q

What is the most common cyst that is Odontogenic?

A
  • Dentigerous Cyst
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3
Q

What are some examples of Odontogenic cysts?

A
•	Dentigerous Cyst
•	Eruption Cyst
•	Odontogenic Keratocyst (OKC) 
      o	WHO: Keratocystic Odontogenic Tumor (KOT)
      o	Associated: Gorlin syndrome
•	Orthokeratinzed Odontogenic Cyst (OOC)
•	Gingival Cyst of the Adult
•	Lateral Periodontal Cyst (LPC)
•	Calcifying Odontogeinc Cyst (COC)
      o	AKA Gorlin Cyst
      o	WHO:  Calcifying Cystic Odontogenic Tumor
•	Glandular Odontogenic Cyst (GOC)
•	Buccal Bifurcation Cyst
•	Carcinoma arising in Odontogenic Cysts
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4
Q

What is a type of epithelial Odontogenic Tumor that is an abnormal growth of a cell type that usually develops enamel?

A
  • Ameloblastoma
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5
Q

What are some examples of Odontogenic Epithelial Tumors, Mixed Odontogenic Tumors and Odontogenic Ectomesenchymal Tumors?

A
Tumors of Odontogenic Epithelium
•	Odontogenic epithelial origin:
•	Ameloblastoma
•	Ameloblastic Carcinoma
•	Malignant Ameloblastoma
•	Adenomatoid Odontogenic Tumor (AOT)
•	Calcifying Epithelial Odontogenic Tumor (CEOT)
      o	AKA Pindborg tumor
Mixed odontogenic tumors:
•	Ameloblastic Fibroma
•	Ameloblastic Fibro-odontoma
•	Ameloblastic Fibrosarcoma
•	Odontoma
•	Odontogenic tumors
Odontogenic ectomesenchyme tumors:
•	Central Odontogenic Fibroma (COF)
•	Peripheral Odontogenic Fibroma
•	Odontogenic Myxoma
•	Cementoblastoma
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6
Q

What is a Cyst that originates by separation of the Follicle from around the Crown of an Unerupted tooth, develops by accumulation of fluid between the reduced enamel epithelium and the tooth crown, is the MOST common Developmental cyst, most often involve Mandibular 3rd Molars, asymptomatic and discovered on routine XRAY, can grow to considerable size and expand bone. Radiographically looks like a Unilocular radiolucency associated with crown of unerupted tooth and Well-defined and usually sclerotic border?

A
  • Dentigerous Cyst
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7
Q

What is a Soft tissue analogue of the dentigerous cyst, Appears as a soft, translucent swelling in the gingival mucosa overlying the crown of an erupting tooth, Usually seen in children younger than 10?
Surface trauma may result blood to accumulate in the cystic fluid, which imparts a blue or purple color, what is this called?

A
  • Eruption Cyst

- Eruption Hematomas

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8
Q

What has a 30% Recurrence Rate, is Associated with a syndrome, Arises from cell rests of the dental lamina, Posterior mandible is the most common location, Grow in an Anterior-Posterior direction, Doesn’t cause bone expansion, Radiographically: Smaller lesions: well-defined, unilocular RL with corticated margins, Larger lesions: Multilocular. Histologically: Thin friable wall of 6-8 cells thick, and may include ‘daughter cysts’. An unerupted tooth is involved in 1/3 of cases?
World Health Organization renamed this to what?
Should be further evaluated to rule out what?

A
  • Odontogenic Keratocyst (OKC)
  • Keratocystic Odontogenic Tumor (KOT)
  • Gorlin syndrome
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9
Q

For a unilocular radiolucency involving a tooth (4)? For multilocular (4)?

A
  • Dentigerous Cyst, Odontogenic Keratosis, Ameloblastoma and Central Giant Cell Granuloma.
  • Same as unilocular
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10
Q

What is AD inherited, can be a system complex characterized by Multiple basal cell carcinomas (BCCAs), Odontogenic keratocysts, Calcification of the falx cerebri and Rib anomalies (splayed or bifid ribs). Appear around puberty and appear on skin not exposed to sunlight?
What is this also called?
What chromosome and gene are involved?

A
  • Nevoid Basal Cell Carcinoma Syndrome
  • Gorlin Syndrome
  • Chromosome 9, PTCH gene
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11
Q

What is Derived from rests of dental lamina (rests of Serres), has a Striking Predilection to occur in the mandibular canine & premolar area (6-75%), Invariably located on the facial gingiva or alveolar mucosa, Painless, dome-like swellings which are less than 5mm, and May be blue in color? This is the soft tissue counterpart of what bony structure?

A
  • Gingival Cyst of the Adult

- Lateral periodontal cyst

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12
Q

What is the developmental odontogenic cyst which typically occurs along the lateral root surface, Arises from rests of dental lamina, Striking predilection to occur in the mandibular Premolar-Canine/Lateral Incisor area, and the Teeth are vital?
This is the Intrabony counterpart of what what soft tissue entity?
Occasionally, the lesion may appear polycystic, what are these called?

A
  • Lateral Periodontal Cyst
  • Intrabony counterpart of the Gingival Cyst of the adult
  • Botryoid odontogenic cyst (“grapelike”)
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13
Q

What is when 65% are found in the Incisor-Canine areas, 20% are associated with odontomas, 1/3 (30%) are associated with an unerupted tooth (usually canine), and histologically has Ghost cells which can calcify?
What is this also known as?

A
  • Calcifying Odontogenic Cyst (COC)

- Gorlin Cyst

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14
Q

What are Inflammatory cyst with uncertain pathogenesis, Characteristically develops on the buccal aspect of the mandibular First Permanent molar, Occurs in children (avg age of 10), Patient may experience tenderness, swelling, or foul-tasting discharge. Perio probing usually reveals pocket formation on the buccal aspect, and 1/3 have bilateral involvement?

A
  • Buccal Bifurcation Cyst
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15
Q

What is the Most common clinically significant odontogenic tumor, Tumors of odontogenic epithelial origin, 85% occur in the mandible, usually the Molar-Ascending Ramus area, If untreated can grow to grotesque proportions, radiographically appears as “Soap bubble”, “Honeycombed”, and Buccal and lingual cortical expansion is frequently present. Resorption of roots is common. Has Palisading, and Reverse polarity?
There are three types, what are they and which are most common?
There are also 6 patterns, what are they and which are most/least common?
What makes the Desmoplatic Pattern unique?
What is the most common resection treatment used and reoccurrence rate?

A
  • Ameloblastoma
  • Types:
    o Conventional solid or multicystic – 85%
    o Unicystic – 15%
    o Peripheral – 1%
  • Patterns:
    o Follicular – most common
    o Plexiform – 2nd most common
    o Acanthomatous – has keratin
    o Granular cell
    o Basal cell – very rare
    o Desmoplastic – see below
  • Predilection for the anterior maxilla and May be mixed radiolucent-radiopaque.
  • Marginal Resection, reoccurrence 50-90%
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16
Q

What occurs in young patients, ages 10-20, Very uncommon in patients over the age of 30 if so: Striking tendency to occur in the anterior jaws, Mx>Md and F:M 2:1. Asymptomatic and discovered during XRAY to determine why a tooth hasn’t erupted, In 75% of cases, the tumor is a circumscribed and unilocular RL involving the Crown of an Unerupted tooth, Most often a Canine tooth that is impacted, Lesion may contain fine, Snowflake calcifications via XRAY, Tumor has a thick fibrous capsule, recurrence doesn’t occur; lesion is completely benign & aggressive behavior has not been documented?

A
  • Adenomatoid Odontogenic Tumor (AOT)
17
Q

What most commonly have a presenting sign is a painless slow-growing swelling, Amyloid-like extracellular material; positive for Congo red, which exhibits an apple-green birefringence when viewed under polarized light, radiographically Margins are typically scalloped & well-defined; may be corticated or ill-defined are Frequently associated with an impacted tooth (most often a mandibular molar) and Contains calcified structures of varying size and density (Some believe the calcifications are prominent around the crown in a “Driven-Snow” pattern and Occurs in 10%)?
What is this also known as?
What are the Calcifications with concentric rings form in the amyloid-like areas in these?

A
  • Calcifying Epithelial Odontogenic Tumor (CEOT)
  • Pindborg Tumor
  • Liesegang rings
18
Q

True mixed tumor - both epithelial and mesenchymal tissues are neoplastic, Occur in younger patients – usually before age 20, 70% are located in the posterior mandible, 75% are associated with an unerupted tooth, and 50% of them develop in the setting of a recurrent ameloblastic fibroma, and is basically a dentigerous cyst found in children?

A
  • Ameloblastic Fibroma
19
Q

Histologically appears similar to ameloblastic fibroma, except it also has enamel and dentin, Avg age is 10, Occurs in the posterior jaws, Small lesions are asymptomatic; large lesions are associated with a painless swelling, Contains varying amounts of calcified material, and Typically associated with an unerupted tooth?

A
  • Ameloblastic Fibro-Odontoma
20
Q

What is Typically on the mesenchymal portion of the lesion shows features of malignancy, 80% occur in the mandible, Patients complain of pain and swelling, Via XRAY, the lesion appears as an ill-defined, destructive radiolucent lesion, and 20% will succumb to disease, usually due to uncontrolled local growth? This is the Malignant counterpart of what?

A
  • Ameloblastic Fibrosarcoma

- Ameloblastic fibroma

21
Q

What is the Most common odontogenic tumor, Completely asymptomatic, Relatively small and discovered via XRAY when films are taken to determine the reason for failure of tooth eruption, and Usually associated with an unerupted tooth? What are the two different types?

A
  • Odontoma
  • o Compound: Composed of multiple, small, toothlike structures, Appears as a collection of toothlike structures of varying size and shape, and Surrounded by a narrow RL zone.
    o Complex: Conglomerate mass of enamel and dentin; bears no anatomic resemblance of a tooth, Calcified mass with the radiodensity of a tooth, and Surrounded by a narrow, RL rim.