Chapter 14: Medication Information Flashcards
What two terms are used interchangeably in the health care field?
Drugs and Medications
Are substances prescribed for treatment that produce therapeutically useful effects?
Medications
Denotes substances used in diagnosis, treatment, or disease prevention, or as a component of a medication?
- replace a missing substance in the body
Drugs
medications made from plants
digitalis
medications that come from animal sources
heparin
medications that are produced by microorganisms
penicillin
Indicates its chemical family
generic
given to a drug by its manufacturer
Proprietary or trade names
Resources on medications are:
- physician’s desk reference (PDR)
- clinical pharmacology
Setting the standards for control of drugs
FDA (Food and Drug Administration)
Safety of workplace environment
OSHA
standards for control of drugs:
These standards include strict rules concerning efficiency (effectiveness), purity, potency (strength), safety, and toxicity (potential for harm) of both prescription and nonprescription over-the-counter (OTC) medications.
term that means effectiveness
Efficiency
Term that means strength
Potency
term that means potential for harm
Toxicity
The study of the way the body processes a drug and includes how drugs are absorbed, reach their site of action, are metabolized and exit the body
-Affects the response of persons to drugs (Varies according to age, physical condition, sex, weight, and immune status)
Pharmacokinetics
is a process involving the movement of a drug from the site of administration into the systemic circulation to produce a desired effect.
Absorption
How are oral medications absorbed?
Oral medications are absorbed through the mucosal lining of the gastrointestinal tract
How are other medications injected or absorbed?
Other medications are injected and absorbed through the blood vessels in the muscles, subcutaneous tissues, or dermal layers.
When medications are injected directly into a vein or artery
No absorption needed
is the means by which a drug travels from the bloodstream to the target tissue and site of action.
- This process depends on adequate circulation. Drugs act more quickly in organs with an abundant blood supply, such as the liver, heart, brain, and kidneys.
Distribution
is the process by which the body transforms drugs into an inactive form that can be excreted from the body.
Metabolism
Where do most drug metabolism occur?
In your liver
where enzymatic action transforms a drug into metabolites (products of metabolism) that can be excreted via the intestinal tract or the kidneys.
The liver
refers to the elimination of drugs from the body after they have been metabolized.
Excretion
Some of examples of how drugs may be excreted
Drugs may be excreted by way of the kidneys, intestines, lungs, breast milk, or exocrine glands.
- Portions of some drugs can escape metabolism and be excreted unchanged in urine or feces.
are the chief organs of excretion
The kidneys
Postoperative patients who are under anesthesia are encouraged to what?
are encouraged to cough and breathe deeply to help clear their bodies of the anesthetic agent
Volatile substances such as alcohol and certain anesthetics are what?
are excreted through the lungs.
Defined as the study of the effects of drugs on the normal physiological functions of the body
Pharmacodynamics
A drug that produces a specific action and promotes the desired result
Agonist
A drug that attaches itself to the receptor, preventing the agonist from acting
Antagonist
Toxic effects of medication can occur when the drug accumulates in the body resulting in
- Overdose
- Impaired elimination
- Advanced age
- Impaired metabolism
- Drug sensitivity
- purpose of the medication
- usually drug binds to a receptor sites on cells
examples : pain relief, blood pressure controlled, reduce inflammation
Therapeutic Effect
- effect other than the desired
- related to the chemical and therapeutic characteristics
- something you don’t want
- ex: nausea, headache, insomnia, dry mouth
Side effect
- poisonous, potentially lethal
- inadequate excretion, impaired metabolism, overdose, or drug sensitivity
- ex: respiratory depression, kidney failure
Toxic effect
- overreaction, underreaction, unusual reaction
- cause: unknown, unique to individuals
- example: sedative cause anxiety, appetite suppressant increases appetite; mild stimulant causes extreme excitation
Idiosyncratic effect
- characteristic response to an allergen
- cause: previous sensitization to an initial dose of the medication or one of its components
- example: hives, asthma, attack, bronchospasm
Allergic response
-responses to combined drugs that differ from their individual effects
- cause: chemical or physiological drug interaction
- example: combination of hypertension medication and diuretic drug causes weakness and fainting
Synergistic effect
Toxic effects of medication can occur when the drug accumulates in the body resulting in
- overdose
- impaired elimination
- advanced age
- impaired metabolism
- drug sensitivity
Specific drugs that treats a toxic effect is called an
Antidote
A type of reaction that occurs when a patient overreacts or underreacts to a drug or has an unusual reaction
Idiosyncratic reaction
This type of reaction occurs when a patient has been sensitized to the initial dose of a medication and developed an reaction to the allergen and related drugs
Allergic reaction
Medications Used to Treat Allergic Reactions
-Termed antihistamines
-Diphenhydramine hydrochloride (Benadryl) is more commonly used in imaging.
-Epinephrine (adrenaline) is administered for severe reactions
-Category includes antiseptics, such as Betadine.
-Antibiotics are also in this category.
-used to disinfect
Antimicrobials
Used to control or prevent seizures
- example ( diazepam) (Valium) and dilantin
Anticonvulsants
Used to treat chronic cardiac arrhythmias
-amiodarone (Pacerone)
-adenocard
-coradarone
-isoptin
-pronestyl
-xylocaine
Antiarrhythmics
-Relieve pain without causing a loss of consciousness
-Range from controlled narcotics to over-the-counter (OTC) medications, such as ibuprofen and aspirin
- if is a controlled substance (addicted to) increase chance of abuse
Analgesics
induce sleep
narcrotic
Exert a quieting effect, often inducing sleep.
Sedatives and tranquilizers
Reduce anxiety better than sedatives
- example: lorazepam (ativan) and diazepam (valium)
Tranquilizers