Chapter 14 Animal water + electrolyte balance Flashcards

You may prefer our related Brainscape-certified flashcards:
1
Q

Explain why water is essential to proper body function, and explain why too much
water can be a bad thing.

A

Essential: Physiological systems of animals operate within a fluid environment (i.e., all the chemical reactions in our body that make life possible occur in aqueous solutions).

Water intoxication occurs when a person drinks so much water that nutrients in the body become diluted to the point that they can no longer “do their jobs”.

The moral of the story: the relative concentrations of water and solutes must be maintained within narrow limits.
• If the water and solute balance in our bodies is disturbed or pushed outside those limits, chemical reactions in our body may stop – along with our lives.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Define “osmoregulation”. Define “osmotic stress”.

A

–> Osmoregulation: the process by which animals control
solute concentrations and balance water gain and loss.
–> Osmotic stress occurs when water and solute concentrations are
different from their set point (i.e. are abnormal).

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

State how excretion of metabolic wastes is functionally linked to osmoregulation.

A
• Animals must also deal with potentially hazardous 
metabolic wastes (esp. ammonia).
• Several different mechanisms have evolved for excretion – the process that rids the body of nitrogenous and other metabolic wastes. 

It is because it is a mechanism used to get rid of solutes and maintain water balance

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Define “electrolyte”.

A

compounds that dissociates into ions when dissolved in water.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

List 4 ways that animals gain water and 4 ways that animals lose water.

A

– How do animals gain water?
1. Absorbing it via osmosis
2. Drinking
3. Eating
4. By-product of cellular respiration
• How do animals lose water?
1. In urine
2. In feces
3. Via evaporation (panting, sweating, from moist surfaces)
4. Via osmotic loss

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Compare and contrast an osmoconformer to an osmoregulator.

A
  1. Be an osmoconformer - be isotonic with your surroundings.
    • Do not actively regulate the osmolarity of their tissues.
    • Do regulate the composition of solutes inside their tissues.
    • Even an animal that conforms to the osmolarity of its surroundings does regulate its internal composition to maintain homeostasis.
    • Most marine invertebrates, including sponges, jellyfish, and flatworms.
  2. Be an osmoregulator - expend energy to control the osmolarity of body fluids that are not isotonic with the outside environment.
    • Must discharge excess water if it lives in a hypotonic environment or take in water if it inhabits a hypertonic environment.
    • Must also actively control concentration and composition of solutes.
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Describe the water and electrolyte challenges faced by organisms in different environments.

A

Tissues are hypotonic to surrounding environment.
Challenge: Tend to lose water and gain electrolytes.

Tissues are hypertonic to surrounding environment.
Challenge:Tend to gain water and lose electrolytes.

In hot terrestrial environments
Challenge:Risk of dehydration due to evaporation ofwater.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Explain how the osmoregulatory problems of freshwater animals differ from those of marine animals.

A

The body fluids of freshwater animals must be hyperosmotic because animal cells cannot tolerate salt concentrations as low as those of lake or river water. where as in marine environments they must maintime hypotonic because their is to much salt in the water

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Explain why osmoregulation has an energy cost.

A

Diffusion tends to equalize concentrations in a system  must expend energy to maintain the osmotic gradients that move water in and out.
• NOTE: Water is not actively transported.
• Animals use active transport to manipulate solute concentrations in their body fluids –> creates osmotic gradients that cause water to flow in or out.

The energy costs of osmoregulation depends on:
• How different an animal’s osmolarity is from its surroundings,
• How easily water and solutes can move across an animal’s body surface
• How much membrane transport work is required to pump solutes.
• Example: Osmoregulation accounts for 5% of the BMR of many marine and freshwater bony fishes, but 30% of BMR of brine shrimp.
• Minimizing the osmotic difference between the body fluids and the surrounding environment –> the energetic cost of osmoregulation.
• Consequently, animals that live in freshwater tend to have lower solute concentrations in their body fluids than their closest relatives that live in salt water.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Explain what is it about nitrogenous waste that makes it difficult for most animals to deal with.

A
  • Most metabolic wastes must be dissolved in water when they are removed from the body –> impacts water balance.
  • When proteins and nucleic acids are broken down for energy or converted to other organic products, enzymes remove nitrogen in the form of ammonia (NH3)
  • Readily forms NH4+ = small and very toxic molecule.
  • Some animals excrete ammonia directly, but many species first convert ammonia to other compounds that are less toxic, but more costly to produce.
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Ammonia, which animals, why its adaptive for particular group and the main advantages and disadvantages

A
  • Can only be tolerated at very low concentrations therefore animals that excrete ammonia need access to lots of water!
  • Most common in aquatic species.
  • Advantage: Energetically cheap.
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Urea which animals, why its adaptive for particular group and the main advantages and disadvantages

A

• Because ammonia is so toxic, it can be transported and excreted only in large volumes of very dilute solutions –> not suitable for most terrestrial animals and many marine organisms.
• Mammals, most adult amphibians, sharks, and some marine bony fishes and turtles excrete urea.
• Synthesized in the liver by combining ammonia + CO2
and is excreted by the kidneys.
• Main advantage = low toxicity. Can be transported in the circulatory system and stored safely at high concentrations –> reduces the amount of water needed for nitrogen excretion.
• Main disadvantage = must expend energy to produce it from ammonia.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Uric acid which animals, why its adaptive for particular group and the main advantages and disadvantages

A
  • Land snails, insects, birds, and many reptiles excrete uric acid as the main nitrogenous waste.
  • Advantages:
  • Relatively nontoxic.
  • Largely insoluble in water - can be excreted as a semisolid paste with even less water loss than urea –> good option for arid environments.
  • Can be stored within a shelled egg as a harmless solid.
  • Soluble wastes (e.g., urea) can diffuse out of a shell-less amphibian egg or be carried away by the mother’s blood in a mammalian embryo.
  • Shelled eggs of birds and reptiles are not permeable to liquids - soluble nitrogenous wastes trapped within the egg could accumulate to dangerous levels (even urea!).
  • Disadvantage: Even more energetically expensive to produce!
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Compare the three nitrogenous waste products in regards to energetic and water costs.

A

Ammonia: energetically cheap, LOTS OF WATER
Urea: Uses energy, reduced amount of water needed
Uric Acid: Expensive on energy, less water

• Amount of water required:
Ammonia > Urea > Uric acid
• Amount of energy required:
Ammonia < Urea < Uric acid

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Explain the osmolarity of a shark relative to its environment and how this osmolarity is maintained.

A

Sharks - marine osmoconformer, but still has to regulate salt levels.
Unlike most marine fish, marine sharks and most other
chondrichthyans have tissues that are isotonic to seawater.
• Like bony fishes, sharks have an internal salt (NaCl) concentration that is lower than that of seawater  salt diffuses into body  Sharks need to excrete excess salt.
• Unlike bony fish, body fluids contain high concentrations of urea and TMAO.
• Salts, urea, and TMAO result in an osmolarity very close to that of seawater, and actually slightly higher than it –> water slowly diffuses into body; removed in urine.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Explain the role of the rectal gland in sharks and how the coordinated action of 4 membrane proteins accomplish this goal.

A

Explain how an electrochemical gradient for sodium ions makes it possible for water and ions to passively move across the epithelial cell membranes of the shark rectal gland.

1) Na+/K+ pump transports Na+ out of epithelial cells of gland into extracellular fluid
- -opposite direction of what cell “wants” BUT sets up electrochemical gradient favoring diffusion of Na+ into the cell
2. Co-transporter uses electrochemical gradient favoring Na+ movement into cell to transport Cl- and K+ into cell against their concentration gradients–> no additional ATP used
3) K+ diffuses out of cell into extracellular fluid via K+ channe. Cl- diffuses out of cell into lumen via chanell–> creates electrical gradient favoring movement of Na+ into lumen
4) Na+ diffuses into lumen through spaces inbetween cells

17
Q

Explain how an electrochemical gradient for sodium ions makes it possible for water and ions to passively move across the epithelial cell membranes of the shark rectal gland.

A

• The sodium and chloride ions are not transported against their electrochemical gradients directly.
• Instead, an ATP pump and a cotransporter are used to set up strong electrochemical gradients.
• The Ions then move in the direction the cell “wants” by
diffusing down their gradient.

18
Q

List 3 structures observed in other organisms that use a similar mechanism as that observed in the shark rectal gland.

A

Marine birds and some reptiles drink salt water and must excrete NaCl.
• These animals have salt-excreting glands in their nostrils that function much like the shark rectal gland.
• The gills of bony fish contain specialized “chloride cells”.
• Are configured much like the cells lining the shark rectal gland.
• Excrete excess salt or uptake needed salt to maintain electrolyte balance.
• Mammals have a similar configuration of pumps, cotransporters, and channels in their kidneys

19
Q

. Explain 2 factors that contribute to dehydration in insects and, in light of these factors, explain how water loss is minimized.

A

1) Insects have high surface-area-to-volume ratios.
2) Insects breathe via exposure of a thin layer of epithelium to the atmosphere.
• Both high loss (evaporation) of water!

How do insects minimize water loss during gas exchange?
• Tracheal system
• Openings to the tracheal system = spiracles
• Muscles just inside each spiracle open and close the
pore.
• If an insect is under osmotic stress, it will close its spiracles and wait until conditions are better to resume activity.

How do insects minimize evaporation from their body
surfaces?
• Water-impermeable waxy coating on the exoskeleton minimizes evaporation from the body surface.

20
Q

Explain how the Malpighian tubules and hindgut function to maintain water and electrolyte balance of an insect’s hemolymph.

A

Malpighian tubules
• Large surface area
• In direct contact with the hemolymph
• Empty into the hind gut.
• Produces pre-urine.
• Pre-urine is then processed and modified in the hindgut prior to excretion
• Conserves water and maintains water and electrolyte balance of the hemolymph.

21
Q

Explain how the above system ensures that waste products are expelled and valuable nutrients are retained.

A

The reabsorption of molecules in the hindgut is both highly selective and tightly regulated.
• The protein pumps and channels involved in reabsorption are specific to certain molecules.
• Ensures that waste products are expelled and valuable products are retained.

22
Q

State how the above system responds to the condition of the organism.

A

Pumps and channels are activated and deactivated in response to osmotic stress.
• The system allows well-hydrated insects to produce urine that is hypotonic to their hemolymph and dehydrated insects to produce urine that is hypertonic to hemolymph.

23
Q

Describe the structure of the mammalian kidney.

A

Kidney: Organ responsible for regulating water and
electrolyte balance in vertebrates, and where nitrogenous
wastes are removed from the blood and eliminated in the
urine.

Nephrons are the basic functional unit of the kidney.
• Each consists of a single long tube and a ball of capillaries = glomerulus.
• Glomerulus is surrounded by a cup-shaped swelling =
Bowman’s capsule.
• Together, Bowman’s capsule + glomerulus = renal corpuscle.

24
Q

Identify and describe the function of the renal corpuscle

A

Renal corpuscle serves as a filtration device:
• Blood pressure forces fluid from the blood in the glomerulus –> pores in the capillaries –> slits in
the surrounding cells –> lumen of Bowman’s capsule.
• Size dependent filtration: permeable to water + small solutes, but not blood cells, proteins…etc.
• Filtration process does not require any ATP.

25
Q

Identify and describe the function of proximal tubule

A

Proximal tubules function in the active transport of selected molecules out of pre-urine; water follows along
osmotic gradient.
• Both water and valuable nutrients that are in the pre-urine are returned to the body!

26
Q

Identify and describe the function of loop of Henle

A

Functions as a countercurrent exchanger.
• Unlike countercurrent system involved in thermoregulation:
• Loop sets up an osmotic gradient.
• Exchange does not happen between the descending and ascending portions of the loop, but between the loop
and the cells surrounding the loop.

27
Q

Identify and describe the function of collecting duct

A

• Collecting duct
• Permeable to water, but not to salt.
–> Water moves by osmosis out of filtrate as the filtrate travels down collecting duct.
–high Solute concentration in filtrate increases.
• In inner medulla, the duct becomes permeable to urea.
• Because of the high concentration of urea in the filtrate, some diffuses out of duct.
– Along with NaCl, contributes to high osmolarity of interstitial fluid in medulla.

28
Q

Briefly state the goal and explain the mechanism used to accomplish renal corpuscle

A

Renal corpuscle serves as a filtration device:
Blood pressure forces fluid from the blood in the glomerulus –> pores in the capillaries –> slits in
the surrounding cells –> lumen of Bowman’s capsule.

29
Q

Briefly state the goal and explain the mechanism used to accomplish proximal tubule

A

The pumps and cotransporters recover water and valuable nutrients, but leave behind wastes.

30
Q

Briefly state the goal and explain the mechanism used to accomplish loop of Henle

A

Functions as a countercurrent exchanger.

Descending limb is permeable to water and not solutes, ascending limb is permeable to solutes and not water

31
Q

Briefly state the goal and explain the mechanism used to accomplish collecting duct

A

An osmotic gradient is created and maintained due to the
countercurrent flow of material through the nephron, allowing for reabsorption of water with the minimal possible expenditure of energy!

32
Q

Compare the composition of blood plasma to that in the Bowman’s capsule.

A

Mixture mirrors the relative concentrations of solutes in blood plasma.

33
Q

Beginning with the Bowman’s capsule, explain the changes in the composition of the filtrate as it moves through the proximal tubule, descending limb of the loop of Henle, ascending limb of the loop of Henle, and the collecting duct.

A

Bowmans capsule: Mixture mirrors the relative concentrations of solutes in blood plasma….. proximal tubule: he pumps and cotransporters recover water and valuable nutrients, but leave behind wastes…. descending limb of the loop of Henle: is permeable to water, but not salt, as interstitual fluid goes down the descending limb its solute concentration increase…. Ascending limb of Henle: permeable to solutes but not water as the interstitial fluid.. collecting duct: Water moves by osmosis out of filtrate as the filtrate travels down collecting duct. Solute concentration in filtrate increases.

34
Q

Explain how the structure of the proximal tubule is well suited to its function .

A

• Epithelial cells of this tubule have a series of small projections called microvilli facing the lumen.
–> What is the purpose of these microvilli? ABSORPTION
• Epithelial cells of the proximal tubules are also packed with mitochondria
–> Which suggests what?
Mitochondria is needed to run the Na+/K+ pumps located on the basal end of the proximal tubule cells. With all the reabsorption of Na….it needs to pump out the sodium out the basal end and Na/K pumps require ATP to function. Without sufficient mitochondria… the Na/K pumps would stop working and reabsorption of things like Na would greatly decrease.

35
Q

Explain how the countercurrent flow of fluid through the loop of Henle, combined with changes in permeability of the loop to water and solutes, results in a self-reinforcing system.

A

The presence of an osmotic gradientstimulates water and ion flows that in turn maintain an osmotic gradient

1) The movement of Na+ and Cl- from the ascending limb into the surrounding tissue increases the osmolarity outside the descending limb
- -> results in flow of water out of the filtrate in the descending limb via osmosis

2) The loss of water from the descending limb increases the osmolarity of the filtrate entering the ascending limb
- -> triggers the passive movement of ions out of the filtrate, reinforcing the osmotic gradient

36
Q

Explain how the collecting duct contributes to the high osmolarity of the medulla.

A

In inner medulla, the duct becomes permeable to urea.
• Because of the high concentration of urea in the filtrate, some diffuses out of duct.
–>Along with NaCl, contributes to high osmolarity of
interstitial fluid in medulla.

37
Q

Explain how ADH influences the characteristics of urine.

A

Hormones control the permeability and activity of the
distal tubules and collecting duct  allows volume and
osmolarity of urine to be adjusted according to animal’s
condition.

38
Q

Compare and contrast the 3 osmoregulatory systems discussed in this lecture.

A

Compare:
–Collecting duct and descending limb are permeable to water.

Contrast:

  • -Ascending limb is permiable to solutes and not water, where as collecting duct and descending limb are permeable to water and not solutes
    • All self- reinforced