Chapter 14 Flashcards
What are pathogens:
Disease-causing microorganisms
Pathogenic microorganisms have special properties that allow them to invade the human body or produce toxins:
what are these??
When does a state of disease occur? m
When a microorganism overcomes the body’s defenses
Pathology:
The scientific study of disease
Pathology is concerned with:
- etiology (cause)
- pathogenesis (development)
- effects of disease
What is infection:
Invasion and growth of pathogens in the body
What is a host:
An organism that shelters and supports the growth of pathogens
What is disease:
-an abnormal state in which parts or all of the body is not properly adjusted or is incapable of performing normal functions
Human Microbiome: microorganisms begin colonization in and on the surface of the body soon after birth
True
Human Microbiome: microorganisms that establish permanent colonies inside or on the body without producing disease make up the
normal microbiota
What is microbial antagonism:
the normal microbiata can prevent pathogens from causing an infection; this phenomenon is known as microbial antagonism
Relationships between the normal microbiata and the host: What is microbial antagonism:
the normal microbiata can prevent pathogens from causing an infection; this phenomenon is known as microbial antagonism
Relationships between the normal microbioata and the host: Normal microbioata and the host exist in symbiosis
living together
Relationships between the normal microbiata and the host:
the three types of symbiosis are:
- commensalism (one organism benefits and the other is unaffected)
- mutualism (both organisms benefit)
- parasitism (one organism benefits, one is harmed)
Opportunistic Microorganisms: Opportunistic Pathogens
Don’t cause disease under normal conditions; but do cause disease under special conditions
The Etiology of Infectious Diseases: Koch’s Postulates
-Koch’s postulates are criteria for establishing that specific microbes cause specific diseases
1) the same pathogen must be present in every case of the disease
2) the pathogen must be isolated in pure culture
3) the pathogen isolated from pure culture must cause the same disease in a healthy, susceptible laboratory animal
4) the pathogen must be re-isolated from the inoculated laboratory animal
The Etiology of Infectious Diseases: Koch’s Posulates
- Koch’s postulates are modified to establish etiologies of diseases caused by viruses and some bacteria, that cannot be grown on artificial media
- Some diseases, such as tetanus, have unequivocal signs and symptoms
- Some diseases, such as pneumonia and nephritis, may be caused by a variety of microorganisms
- Some pathogens, such as S. Pyogenes, cause several different diseases
- Certain pathogens, such as HIV, cause disease in humans only