Chapter 14 Flashcards
Reasons for variation: Random assortment
Random assortment of chromosomes during meiosis = large number of possible combinations of chromosomes.
Variation: Crossing over
Of chromatids during meiosis = parts of chromatids attaching to different chromatids - changed sequence of alleles.
Variation: Non-disjunction
1 or more members of chromosomes pair fail to separate during meiosis.
Variation: Random fertilisation.
Infinite numbers of possible combinations of alleles in the offspring.
Variation: Mutations
Permanent changes in the DNA of a chromosome = totally new characteristic.
Changing the allele frequency.
Natural selection?
Process by which species become adapted to its environment - selection of favourable, strong genes
Having a survival advantage, passing their characteristics onto future generations
Random genetic drift?
Random, non-directional variation in allele frequencies
Due to chance events
Most powerful in small, isolated populations
Religious groups
Example of random genetic drift
“Dunkers”
- USA, originally from Germany
- no marriage outside their group, no interbreeding (religious beliefs)
Founder effect
When a small group moves away from homeland, establishing a new community that tends to expand
Their allele frequencies do not reflect the gene pool of the original population
Migration
Gene flow = movement from one population to another
If immigrants to certain country bring alleles that aren’t already in the population, frequency of alleles of that gene are altered
Two main barriers to gene flow?
Geographical - oceans, mountain ranges, deserts
Sociocultural - language, education and social/economic status
Genetic disease?
Allele causing inherited disease (fatal) would eventually fade from population as those with the allele die and therefore don’t pass on their gene.
Examples of genetic diseases: Tay-Sachs
Hereditary disease, occurring most frequently in those with Jewish descent
Worldwide: low, 1 : 500,000
Ashkenazi Jews: high, 1 : 2,500
Tuberculosis and Tay-Sachs
Heterozygous carriers of Tay-Sachs have an increased resistance to tuberculosis
As of discrimination, Jews were found in ghettos (isolated) which therefore began to decrease the spread or the disease as heterozygous carriers survived and reproduced
Examples of genetic diseases: Thalassaemia
Anaemia resulting from defects to haemoglobin, high frequency in people of a Mediterranean descent
Only marrying each other, isolating themselves
Examples of genetic diseases: Sickle cell anaemia
Mainly occurs in those of black African ancestry
Results in sickle shaped RBC’s
Unable to carry as much O2 so they stick and clot together
What’s the difference when you only have the sickle cell trait?
Mild sickling
Has a certain advantage: providing resistance to malaria
What is evolution?
Gradual change in the characteristics of a species overtime
Darwin’s theory: based on three observations
- Variation - variation within a species, but similar characteristics within a family
- Birth rate - all living organisms reproduce at a greater rate than their available food supply (overcrowding)
- Nature’s balance - although birth rate is high, number of species remain relatively similar (survival of the fittest, struggle for existence)
Struggle for existence and survival of the fittest
Darwin concluded their must be a struggle for existence and those with characteristics best suited are more likely to survive (survival of the fittest)
Examples of natural selection in humans:
Short body, long limbs
Long body, short limbs
Long body, short limb: smaller surface area, smaller heat loss in cold environments (Inuits)
Short body, long limb: increased surface area, larger heat loss in hot environments (Black Africans)
Examples of natural selection in humans:
Sickle-cell anaemia
People with the sickle cell trait have a resistance to malaria
They survive, reproduce, therefore their characteristics are passed on
Speciation steps
- Variation
- Isolation
- Selection
- Speciation
Speciation steps 1. Variation
Range of variation (mix) in an ordinary population
Sharing common gene pool
