Chapter 14 Flashcards

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0
Q

Transcription

A

The first step of gene expression, in which a particular segment of DNA is copied into RNA by the enzyme RNA polymerase
-Both DNA and RNA are nucleic acids, which use base pairs of nucleotides as a complementary language

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1
Q

Base Sequence

A

The order of nucleotide bases in a DNA molecule

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2
Q

RNA

A

The nucleic acid that is used in key metabolic processes for all steps of protein synthesis in all living cells and carries the genetic information of many viruses

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3
Q

mRNA

A

A large family of RNA molecules that convey genetic information from DNA to the ribosome, where they specify the amino acid sequence of the protein products of gene expression

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4
Q

tRNA

A
  • Transfer ribonucleic acid

- a type of RNA molecule that helps decode a messenger RNA (mRNA) sequence into a protein

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5
Q

rRNA

A

A molecular component of a ribosome, the cells essential protein factory

  • Ribosomal RNA
  • rRNA does not make proteins, but makes polypeptides (assemblies of amino acids) that go to make up proteins
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6
Q

Uracil

A

One of the four nucleobases in the nucleic acid of RNA

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7
Q

RNA polymerase

A

An enzyme that produces primary transcript RNA

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8
Q

Promoter

A

DNA sequences that define where transcription of a gene by RNA polymerase begins

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9
Q

Pre-mRNA processing

A
  • includes two different types of segments: exon and introns

- exons are segments that are retained in the final mRNA, where introns are removed in a process called splicing

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10
Q

Exons

A

Any nucleotide sequence encoded by a gene that remains present within the final mature RNA product of that gene after introns have been removed by RNA splicing

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11
Q

Codons

A

A sequence of three DNA or RNA nucleotides that corresponds with a specific amino acid or stop signal during protein synthesis

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12
Q

Genetic code

A

The set of rules by which information encoded in genetic material (DNA or RNA sequences) is translated into proteins (amino acid sequences) by living cells

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13
Q

Anticodon

A

A sequence of three bases that are complementary to a codon in the messenger RNA
-during translation, the bases of the anticodon form complementary base pairs with the bases of the codon by forming the appropriate hydrogen bonds

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14
Q

Amino acids

A

The building blocks of all biological proteins

  • amino acids link together by peptide bonds in a particular order as defined by genes
  • genes are translated by RNA to amino acid chains; the length and order of the amino acid chain then dictates the three-dimensional structure of a polypeptide bond
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15
Q

Peptide bond

A
  • a chemical bond Formed between two molecules when the carboxyl group of one molecule reacts with the amino group of the other molecule, releasing a molecule of water (h2o)
  • this dehydration synthesis reaction (aka a condensation reaction), and usually occurs between amino acids
16
Q

Polypeptide

A

Chains of amino acids

-proteins are made up of one or more polypeptide molecules

17
Q

Initiation

A

The small subunit of the ribosome binding to the 5’ end of mRNA with the help of initiation factors (IF)

18
Q

Ribosome

A

A sphere-shaped structure within the cytoplasm of a cell that is composed of RNA and protein and is the site of protein synthesis

19
Q

Elongation

A

The stepwise addition of amino acids to the growing protein chain

20
Q

Termination

A

Stop of mRNA synthesis at the terminator site

21
Q

Translation

A

The process in which cellular ribosomes create proteins
-in translation, mRNA (produced by transcription from DNA) is decided by a ribosome to produce a specific amino acid chain (polypeptide)

22
Q

Gene

A

The molecular unit of heredity of a living organism
-it is used extensively by the scientific community as a name given to some stretches of deoxyribonucleic acids (DNA) and ribonucleic acids (RNA) that code for a polypeptide or for an RNA chain that has a function in the organism

23
Q

Alternative splicing

A

A regulated process during gene expression that results in a single gene coding for multiple proteins
-in this process, particular exons of a gene may be included within or excluded from the final, processed mRNA produced from that gene