Chapter 14 Flashcards

Prenatal Testing and NTD.

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1
Q

For what is Nuchal Translucency Test use for?

A

To test for All 3 types of Trisomies (13,18&21)

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2
Q

High levels of Inhibin A indicate what?

A

Down Syndrome

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3
Q

What do high and low levels of AFP indicate?

A

High levels indicate NTDs and Low levels indicate + All 3 trisomies

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4
Q

What do high and low levels of Free Beta HCG indicate?

A

High levels indicate Down Syndrome and low levels indicate trisomies 13 and 18

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5
Q

What do low levels of PAPP-A indicate?

A

+ for all 3 trisomies

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6
Q

What do low levels of UE3 indicate?

A

+ for all 3 trisomies

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7
Q

At what time is Amniocentesis performed?

A

15-16 weeks

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8
Q

What type of testing can be drawn from Amniocentesis fluid extract?

A

Karyotyping, DNA testing & AFP from fetal urine

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9
Q

What is the risk of miscarriage from performing an Amniocentesis?

A

1%

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10
Q

At what time is Chorionic Villus Sampling performed?

A

10-12 weeks

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11
Q

How is Chorionic Villus Sampling performed?

A

Transcervical or Transabdominal needle

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12
Q

What is the fluid type obtained in a Chorionic Villus Sampling?

A

Fetal trophoblastic cells

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13
Q

What is the risk of miscarriage from performing a Chorionic Villus Sampling?

A

1%

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14
Q

What is the risk of miscarriage from performing a Maternal Serum Screening?

A

No risk to fetus

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15
Q

When is Maternal Serum collected for screening?

A

16 weeks

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16
Q

What does Maternal Serum test for?

A

Down Syndrom and NTD

17
Q

What are the risk associated with Ultrasounds and fetal echo?

A

No risk to either the baby or the mother.

18
Q

At what time is sex of fetus usually able to be determine with and ultrasound?

A

15 weeks

19
Q

What type of prenatal testing are recommended in the first trimester?

A

Nuchal Translucency, PAPP-A & Free Beta-HCG

20
Q

What type of prenatal testing are recommended in the second trimester?

A

Ue3, AFP and Free Beta-HCG

21
Q

What are the major cause of NTD?

A

Folic Acid deficiency