Chapter 14

Question 1

Two technologies that sped progress of the human genome project in 1991 were

Answer 1

expressed sequence tags and microarrays.

Question 2

Three percent of the human genome project budget was set aside to address issues of

Answer 2

ethics, the law, and society.

Question 3

Who was the first director of the Human Genome Project?

Answer 3

James Watson.

Question 4

Which of the following is a vector used to deliver genes in human gene therapy?

Answer 4

Adeno-associated virus.

Question 5

The term genome was first used by

Answer 5

H. Winkler in 1920.

Question 6

cDNA is copied from

Answer 6

mRNA.

Question 7

A nasal spray for cystic fibrosis patients, which contains adenovirus particles carrying a normal human CFTR gene, is an example of

Answer 7

in vivo gene therapy.

Question 8

A test offered on the Web by a direct-to-consumer genetic testing company genotypes a gene for ability to taste bitter substances. This test is not regulated by the Clinical Laboratory Improvement Amendments (CLIA) because

Answer 8

the test provides information, not a diagnosis.

Question 9

Rita has been diagnosed with HER2 breast cancer, and is prescribed Herceptin. The approach of basing a drug prescription on the results of a single-gene test is called

Answer 9

pharmacogenetics.

Question 10

A genetic counselor might discuss assisted reproductive technologies with a couple who wish to

Answer 10

avoid passing on a disease-causing allele to a child.