Chapter 13 Flashcards
transformation
Griffith (rats) discovered it- a substance from cells of one strain (even when dead) could produce a heritable change in the other stran
Avery
DNase destroyed the transforming substance, the transforming substance is DNA
Hershey-Chase
proteins carry genetic info
Watson and Crick (Franklin)
DNA is a double helix
semiconservative
each parent strand is a template; new molecules have one old and one new strand
conservative
original molecule serves as a template only
dispersive
fragments of DNA are templates, old and new parts are assimilated into new molecules
primase
primer is complementary to the DNA template and is synthesized by it
DNA polymerase
adds nucleotides to the 3’ end until the section is complete, and the primer is degraded
DNA helicase
uses energy from ATP to unwind DNA
Single-strand binding protein
keeps the strands from joining once more
okazaki fragments
synthesis of lagging strand occurs in small, discontinuous stretches called those
ligase
enzyme that joins the okazaki fragments
direction it works in (leading to lagging strands directions)
normal: