Chapter 12 Cell Cycle And Mitosis Flashcards

1
Q

In eukaryotic cells chromosomes are composed of

A

C) DNA and proteins

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2
Q

What is the final result of mitosis in a human

A

Genetically identical 2n somatic cells

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3
Q

If there are 20 duplicated choromosnes in a cell how many centromeres are there

A

20

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4
Q

The first gap in the cell cycle (G1) corresponds to

A

A) normal growth and cell function

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5
Q

The microtubule-organising center found in animal cells is an identifiable structure present during all phases of the cycle specifically it is known as the

A

Centrosome

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6
Q

The mitotic spindle is a microtubular structure that is involved in ________.

A

D) separation of sister chromatids

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7
Q

Metaphase is characterised by ________.

A

A) aligning of chromosomes on the equator

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8
Q

Kinetochore microtubules assist in the process of splitting centromeres by ________.

A

B) creating tension by pulling toward opposite poles

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9
Q

How is plant cell cytokinesis different from animal cell cytokinesis?

A

B) Plant cells deposit vesicles containing cell-wall building blocks on the metaphase plate; animal cells form a cleavage furrow.

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10
Q

FtsZ is a bacterial cytoskeletal protein that forms a contractile ring involved in bacterial cytokinesis. Its function is analogous to ________.

A

A) the cleavage furrow of eukaryotic animal cells

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11
Q

t which phase are centrioles beginning to move apart in animal cells?

A

D) prophase

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12
Q

Which of the following are primarily responsible for cytokinesis in plant cells but not in animal cells?

A

B) Golgi-derived vesicles

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13
Q

The beginning of anaphase is indicated by which of the following?

A

C) Cohesin is cleaved enzymatically.

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14
Q

During which phase of mitosis do the chromatids become chromosomes?

A

B) anaphase

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15
Q

A cleavage furrow is ________.

A

C) a groove in the plasma membrane between daughter nuclei

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16
Q

Several organisms, primarily protists, have what are called intermediate mitotic organisation. These protists are intermediate in what sense?

A

C) They maintain a nuclear envelope during division.

17
Q

Several organisms, primarily protists, have what are called intermediate mitotic organisation. What is the most probable hypothesis about these intermediate forms of cell division?

A

D) They show some but not all of the evolutionary steps toward complete mitosis.

18
Q

Which of the following does NOT occur during mitosis?

A

B) replication of the DNA

19
Q

Motor proteins require which of the following to function in the movement of chromosomes toward the poles of the mitotic spindle?

A

C) ATP as an energy source

20
Q

MPF is a dimer consisting of ________.

A

D) cyclin and a cyclin-dependent kinase

21
Q

Cyclin-dependent kinase (Cdk) is ________.

A

D) an enzyme that attaches phosphate groups to other proteins

22
Q

The M-phase checkpoint ensures that all chromosomes are attached to the mitotic spindle. If this does not happen, cells would most likely be arrested in ________.

A

D) metaphase

23
Q

Which of the following is released by platelets in the vicinity of an injury?

24
Q

Which of the following is a protein maintained at steady levels throughout the cell cycle that requires cyclin to become catalytically active?

25
Which of the following triggers the cell's passage past the G2 checkpoint into mitosis?
B) MPF
26
The cyclin component of MPF is destroyed toward the end of which phase?
D) M
27
Density-dependent inhibition is explained by which of the following?
B) As cells become more numerous, the cell surface proteins of one cell contact the adjoining cells and they stop dividing.
28
Besides the ability of some cancer cells to overproliferate, what else could logically result in a tumour?
B) lack of appropriate cell death
29
Anchorage dependence of animal cells in vitro or in vivo depends on which of the following?
B) response of the cell cycle controls to signals from the plasma membrane
30
Cells from advanced malignant tumours often have very abnormal chromosomes and an abnormal number of chromosomes. What might explain the association between malignant tumours and chromosomal abnormalities?
C) Cell cycle checkpoints are not in place to stop cells with chromosome abnormalities.