CHAPTER 11: ENDOCRINE Flashcards
endocrine glands
ductless organs or groups of cells that secrete hormones directly into the blood or other bodily fluids
three major structural classes of hormones:
1) amines
2) peptides & proteins
3) steriods
amine hormones
derivatives of amino acid tyrosine: examples are epinephrine, norepinephrine, dopamine
how many adrenal glands?
2 (one above each kidney)
adrenal medulla
-located in each adrenal gland, secretes catecholamines (norepinephrine + epinephrine) into BLOOD
-cell bodies do not have axons
adrenal cortex
secretes steroid hormones
dopamine is released into a special circulatory system called:
portal system (which carries it to pituitary gland)
peptide hormones are synthesized as large molecules called _____ which are then cleaved to _____ by proteolytic enzymes in rough ER
preprohormones, prohormones
post-translational modification
prohormone packaged into secretory vesicles by golgi apparatus and then is cleaved to yield active hormone and other peptide chains
peptide hormone processing
synthesis: preprohormone –> prohormone
packaging: prohormone –> hormone
storage: hormone stored in secretory vesicles
secretion: hormone is secreted via exocytosis
vitamin ___ is enzymatically converted in the body to an active steroid hormone
vitamin D
five major hormones secreted from adrenal cortex
-corticosterone
-aidosterone
-cortisol
-androstendione
-dehydroepiandrosterone