Chapter 11 - Emotional Behaviour Flashcards
What systems do emotional situations arouse?
The sympathetic and parasympathetic nervous systems. The sympathetic nervous system stimulates organs essential for flight or fight whilst inhibiting other activities. The parasympathetic nervous system increases digestion and other processes that save energy.
What is the James-Lange theory?
autonomic arousal and skeletal actions come before the feeling of emotion.
situation -> increased HR and running away -> fear.
Event -> appraisal -> action -> emotional feeling
What is pure autonomic failure?
The autonomic nervous system does not regulate HR etc. therefore, James-Lange theory would say that they can’t feel emotions. They report they feel anger less.
What does smiling do?
It increases happiness. Facial expressions are not required for happiness (Mobius syndrome - cannot move facial muscles to smile).
What does emotion involve?
Cognition, feeling and action.
What system is regarded as central to emotion?
The limbic system.
What is the behavioural activation system?
BAS - activity of the left hemisphere, especially its frontal and temporal lobes - marked by low autonomic arousal and a tendency to approach.
What is the behavioural inhibition system?
BIS - activity of the right hemisphere’s frontal and temporal lobes - increased attention and arousal, inhibits action and stimulates emotions such as fear and disgust.
What are impulsive decisions seen as?
Emotional decisions but they are often not. Damage to the PFC causes lack of expression of emotions -damage to the ventromedial PFC - people show inconsistent preferences and are unsure what they like or want. They show less than normal concern for others.
What does emotion is embodied mean?
What you are doing affects how you feel. (i.e. lying down makes it harder to become angry).
What causes aggressive behaviour?
Testosterone in males - young males are more likely to be aggressive.
What inhibits aggression and violent impulses?
Cortisol inhibits aggression and serotonin inhibits violent impulses.
What is serotonin turnover?
The amount of serotonin release and replacement. It is measured by the concentration of 5-HIAA - serotonin’s main metabolite in the CSF.
What does low serotonin turnover result in?
It often results in more aggressive behaviours.
What environmental influences make someone more susceptible to aggression or violence?
abused as children, witnessing violence. More violence as the temperature increases. Genes influence violent behaviour through the autonomic system.
What does monoamine oxidase A do?
MAO>A - after a neuron releases serotonin, dopamine or norepinephrine most returns to the neuron via reuptake. MAOA breaks it down to prevent excessive accumulation. Low activity of MAOA is linked to aggression in people who had troubled childhood experiences. It is an X-linked gene - more men have low-activity of MAOA.
What is the startle reflex?
When a loud noise goes to the cochlear nucleus in the medulla, signals then pons that commands the tensing of muscles, especially the neck muscles (startle reflex). The startle reflex is more vigourous if you are already tense. Startle reflex is related directly to anxiety levels.
What do animal reflexes teach us about the startle reflex?
Present a light or a sound with a shock. When animal has learned the association they show light before a loud noise and then measure the startle response. Startle response is much more rapid when associated with fear of pain.
What role does the amygdala play in the shock reflex?
The amygdala gets much input from pain fibres, vision and hearing. Different paths through the amygdala are responsible for fear of pain, fear of predators and fear of aggressive members of own species. Other parts control changes in breathing, avoidance of unsafe places, learning which particular places are safest and freezing in fear of danger.
What does the output from the amygdala do?
The output from the amygdala to the hypothalamus controls autonomic fear responses. The amygdala has axons to the PFC that control approach and avoidance responses. Axons to the thalamus direct attention towards important stimuli. Axons also extend from the amygdala to the midbrain which connects to the pons controlling startle responses.
What controls long-term emotional arousal?
Long-term emotional arousal depends on the area called the bed nucleus of the stria terminalis. The stria terminalis is a set of axons that connect this nucleus to the amygdala.
What is Urbach-Wiethe disease?
A build-up of calcium in the amygdala that causes damage to it. Results are impaired processing of emotional information and what to fear.
What is panic disorder?
Frequent periods of anxiety and occassional attacks of rapid breathing, increased HR, sweating and trembling.
What brain structures are linked to panic disorder?
Abnormalities in the hypothalamus, decreased activity of GABA and increased levels of orexin (associated with wakefulness and activity).
What is post-traumatic stress disorder?
PTSD is frequent distressing recollections and nightmares, avoidance of reminders of it and vigorous reactions to noises and other stimuli.
What brain structure is impacted by PTSD?
PTSD results in smaller hippocampus.
What are the types of anxiolytic drugs?
Anti-anxiety drugs are benzodiazepines. There are diazepam (Valium), chlordiazepoxide (Librium) and alprazolam (Xanax).
How do benzodiazepines work?
They bind to the GABAA receptors. At the centre of the GABAA receptors is a chloride channel. When open it allows chloride ions to cross the membrane into the neuron, hyperpolarising the cell (the synapse is inhibitory). Surrounding the chloride channel are 4 units each containing one or more sites sensitive to GABA. Benzodiazepines bind to additional sites on 3/4 units. When a benzodiazepine molecule attaches it bends the receptor so that GABA binds more easily.
What areas of the brain do benzodiazepines work?
Exert effects in the amygdala, hypothalamus and midbrain.
What are the side effects of benzodiazepines?
There is a possibility of addiction, sleepiness, block epileptic convulsions and impair memory.
How does alcohol affect anxiety?
Effects of GABA receptors are responsible for anti-anxiety and intoxicating effects. Promotes flow of chloride ions through GABAA receptors.
What does propranolol do?
Blocks reconsolidation of memories. Can be used in treatment of PTSD>
What does a threat to the body do?
It activates a generalised response to stress called the general adaptation syndrome, due to activity in the adrenal glands.
What is the first stage of the general adaptation syndrome?
Alarm - adrenal glands release epinephrine which stimulates the sympathetic nervous system to be ready for action. Also, adrenal glands release cortisol which increases blood glucose, providing extra energy and aldosterone which maintains blood salt and blood volume.
What is the second stage of the general adaptation syndrome?
Resistance - sympathetic response declines but adrenal glands continue secreting cortisol to allow body to maintain alertness.
What happens during the third stage of the general adaptation syndrome?
After intense prolonged stress - exhaustion - individual is tired and inactive nervous and immune systems have no energy to sustain them.
What does stress do?
It activates the sympathetic nervous system and the HPA axis. Activation of the hypothalamus induces the anterior pituitary gland to secrete adrenocorticotropic hormone (ACTH) which stimulates the adrenal cortex to secrete cortisol which enhances metabolic activity, elevates blood levels of sugar and alertness. HPA axis reacts more slowly than autonomic system but dominates response to prolonged stressors. Prolonged stress impacts the immune system and memory.
What is the HPA axis?
The hypothalamus-pituitary-adrenal cortex axis.
What is an autoimmune disease?
The body attacks normal cells.
What are leukocytes?
White blood cells
What are b-cells and what do they do?
Found in bone marrow - secrete antibodies that attach to particular antigens and attacks the cell.
What are t-cells?
mature in the thymus gland - attack intruders directly.
What are natural killer cells?
Attack tumor cells and cells affected with viruses.
How does the body respond to infections?
Leukocytes produce cytokines that combat infections. It also stimulates the vagus nerve and triggers the release of prostaglandins that cross the blood-brain barrier and stimulates the hypothalamus to produce fever, sleepiness, lack of energy and appetite and loss of sex drive.
What does stress do?
It causes the nervous system to activate the immune system to increase the production of natural killer cells and secretion of cytokines. Elevated cytokine level helps to combat infections but trigger postaglandins that reach the hypothalamus. This can cause symptoms such as sleepiness, decreased appetite and elevated body temperature. Exposure to stress can impact on the hippocampus, reducing levels of dendrites and impairing memories dependent on the hippocampus.
Benzodiazepines bind to the GABA-C receptor. T or F
False
If a treatment suddenly lowered your serotonin level:
we could not predict how and when your behavior would change.
The limbic system consists of structures that are believed to be important for which kind of responses?
emotional
Increased fear, anxiety, or panic is related to increased activity of ____ and decreased activity of ____.
CCK; GABA