Chapter 11 – Blood Vessels: Arteriosclerosis

Question 1

What is Arteriosclerosis?

Answer 1

Arteriosclerosis literally means “hardening of the arteries”; it is a generic term reflecting arterial
wall thickening and loss of elasticity.

Question 2

Arteriosclerosisvhave three general patterns, with differing clinical and
pathologic consequences:

Answer 2

• Arteriolosclerosis
• Mönckeberg medial sclerosis
• Atherosclerosis

Question 3

What arteries does Arteriolosclerosis affect?

Answer 3

small arteries and arterioles, and may cause downstream
ischemic injury.

The anatomic variants, hyaline and hyperplastic, were discussed above
in relation to hypertension

Question 4

What is Mönckeberg medial sclerosis?

Answer 4

Mönckeberg medial sclerosis is characterized by calcific deposits in muscular arteries in
persons typically older than age 50.

The deposits may undergo metaplastic change into
bone.

Nevertheless, the lesions do not encroach on the vessel lumen and are usually not clinically significant

Question 5

Mönckeberg medial sclerosis encroach on the vessel lumen and are usually clinically significant

T or F

Answer 5

FALSE