Chapter 11 Flashcards
sum total of all microbes found on a normal human
human microbiome
microbe whose relationship with host is parasitic and results in infection and disease
pathogen
disruption of tissue or organ caused by microbes or their products
infectious disease
an organisms potential to cause disease and is used to divide pathogenic microbes into two groups
pathogenicity
primary pathogens are capable of causing disease in healthy persons with normal immune systems
true pathogens
cause disease when the hosts defenses are compromised or when the pathogens become established in a part of the body that is not natural for them
opportunistic pathogens
to initiate an infection a microbe must enter a tissues of the body by a characteristic route usually the skin r mucous membrane
portal of entry
originating from a source outside the body
exogenous
already existing on or in the body
endogenous
white blood cells that originally engulf and destroy pathogens by means of enzymes and antimicrobial chemicals
phagocytes
produced by strep and staph these substances are toxic to white blood cells
leukocidins
specific chemical product of microbes that is poisonous to to other microbes
toxin
proteins with a strong specificity for a target cell also extremely powerful
exotoxins
a class of bacterial exotoxin that disrupts the cell membrane of red blood cells
hemolysins
red blood cells burst and release hemoglobin pigment
hemolyze
earliest symptoms of disease is the bodies earliest defense called
inflammation
infected person with no symptoms
asymptomatic
spread infectious agent during incubation period
incubating carriers
recuperating patients without symptoms they continue to shed viable microbes and convey infection to others
convalescent carriers
when an infected host can transmit the infectious agent to another host and establish infection in the new host
communicable
an infection indigenous to animals but spread to humans naturally
zoonosis
involves physical contact between infected person and new host
direct contact
infectious agent must pass from and infected host to an intermediate conveyor and from there to another host
indirect transmission
natural non living material that can transmit infectious agents
vehicle