Chapter 11

Question 1

nucleosome

Answer 1

fundamental repeating pattern unit of chromatin
- core particle of DNA wrapped about 2 times with eight histone proteins

Question 2

epigenetic changes

Answer 2

alterations of chromatin or DNA structure that do not include changes in the base sequence but are stable and passed on to descendant cells or organisms

Question 3

DNAse I sensitivity

Answer 3

transcriptionally active genes are sensitive to DNAse I
- when DNA is tightly bound to histone proteins it is less sensitive to DNAse I whereas unbound DNA is more sensitive

Question 4

telomeres

Answer 4

replicates the end of a chromosome

Question 5

denaturation

Answer 5

double stranded DNA in solution is heated, the hydrogen bonds that hold the 2 nucleotide strands together are weakened (melting)

Question 6

hybridization

Answer 6

two single stranded molecules of DNA from different sources will anneal if they are complementary

Question 7

unique sequence DNA

Answer 7

CONSISTS OF SEQUENCES THAT ARE PRESENT ONLY ONCE OR AT MOST A FEW TIMES IN THE GENOME

Question 8

repetitive DNA

Answer 8

exist in mnau copies