Chapter 10_Chromosome Organization And Molecular Structure Flashcards
DNA gyrase
(Topoisomerase II) Introduces negative supercoils using energy from ATP.
Topoisomerase I
Can relax neagtive supercoils.
Chromatin
The DNA protein complex found within eukaryotic chromosomes.
Three types of regions are required for chromosomal replication and segregation.
Origins of replication, centromeres, and telomeres.
Telomeres
Prevent chromosomal rearrangements such as translocations. They prevent chromosome shortening. Protect chromosomes from digestion via enzymes called exonucleases. Second, an unusual form of DNA replication may occur at the telomere to ensure that eukaryotic chromosomes do not become shortened with each round of replication.
Introns
Noncoding intervening sequences
Transposable Elements
Segments of DNA that have the ability to move within a genome
Retroelement
Can be transcribed into RNA, copied into DNA, and inserted into the genome.