Chapter 10 Notes Flashcards
1
Q
Dephosphorylation?
A
hydrolysis RxN similar to peptide cleavage - involved in following equation
phosphorylated protein + water + protein phosphatase -> orthophosphate (Pi)
2
Q
Autoinhibition?
A
sequence comes from within itself - PKA
3
Q
Which AA get phosphorylated in PKA?
A
threonine, serine, tyrosine, histidine
4
Q
What is the main mechanism of PKA?
A
phosphorylation/dephosphorylation
5
Q
sulfation?
A
forms blood clots
6
Q
myristoylalation?
A
alteration of location of molecule (FA); add FA chain to protein molecule and protein can be broken down
7
Q
acetylation?
A
modifies affinity to a target - histones
