Chapter 10 Flashcards

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1
Q

Chemicals from food you eat are used to….

A

provide building blocks to build molecules, to generate energy for your body’s activities, & to assemble essential nutrients that your body cannot produce.

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2
Q

Food supplies over ___ substances that your body needs but cannot produce itself

A

40

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3
Q

Nutrients are

A

the chemicals in the food you eat that help your body perform all its functions
- there are 6 types of nutrients in food: carbohydrates, proteins, fats, vitamins, minerals, & water.

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4
Q

Macronutrients are

A

nutrients that you need in large amounts daily.
- Macronutrients = Carbohydrates, proteins, fats, & water

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5
Q

Micronutrients are

A

nutrients that you need less of on a daily basis
-Micronutrients = Most vitamins & minerals

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6
Q

The food you eat usually contains _______ & ______ molecules

A

large, complex
- they are too big to pass through cell membranes & are not exactly the same as the smaller ones found in your body
- the digestive system must dissemble the food you eat into smaller molecules –> these molecules then become sources of energy, or assemble them into more complex molecules & use them to build and maintain cell structure and function.
- Ex. cheese is made up of proteins that are too large for our cells to use in their present state. Your digestive system dissembles them into their basic “building block” molecules. Your cells then use them to build your own proteins

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7
Q

All organisms use the ______ components to make their molecules

A

same
- Ex. lions, pandas, humans, & trees make their proteins from the same 20 kinds of building block molecules

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8
Q

Carbohydrates are (3)

A

compounds made up of Carbon, Hydrogen, & Oxygen atoms and are major source of energy for your body.
- U can use carbs as an energy source just minutes after a meal or u can store them for later use
- Foods with simple carbs include sugars from fruit, honey, milk

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9
Q

Glucose is (4)

A

is a type of sugar molecule that is a major source of fuel supply for the work done by your cells
- ur cells break down glucose molecules & extract their stored energy
- ur cells use carbon chains of simple sugars as raw material to manufacture other kinds of molecules
- glucose molecules that ur cells don’t use immediately are incorporated into larger carbs or are used to make fat molecules

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10
Q

Starches are

A

complex carbs.
- they are found in foods like whole-grain cereals, bread, rice, & potatoes.
- complex carbs are broken down by ur digestive system into simple sugars –> the simple sugars are absorbed into blood & carried to cells in the body –> excess blood sugar is converted into glycogen

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11
Q

Glycogen is (3)

A

a chain of many glucose molecules
- in humans, most glycogen is stored in the liver and in muscle & fat cells. –> When the body needs energy, it breaks down glycogen, releasing glucose.

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12
Q

Fibre/Cellulose (3)

A

is a type of complex carb
- our digestive system can’t break it down but u need it to include it in ur diet as fibre supplied bulk to help ur muscles move food & wastes through ur digestive system.
- they may have other benefits like reducing the risk of heart disease.

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13
Q

A protein is (5)

A

a complex molecule that is constructed from 20 kinds of smaller molecules called amino acids
- they contribute to almost all ur day-to-day functions. Ex. proteins form hair & muscles, and they provide long-term nutrient storage
- some proteins circulate in the blood & defend the body from harmful micro-organisms
- Other proteins convey messages from one cell to another
- some proteins work with enzymes to control the chemical reactions in a cell

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14
Q

Enzymes are

A

proteins that speed up specific chemical reactions without being consumed in the reaction

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15
Q

Essential amino acids (5)

A

are the 8 amino acids that your cells cannot make from other molecules
- if u lack even 1 essential amino acid, you cannot make protein properly.
- Animal products like meat, milk, eggs, & cheese provide all 8 essential amino acids
- those that don’t eat animal products must eat combinations of plant foods to obtain all the essential amino acids
- some vegetarian combos of complete protein include corn & beans, rice & lentils, and hummus with pita bread

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16
Q

Fats (5)

A

AKA lipids
- are molecules formed from fatty acids & glycerol.
- fats store energy in ur body & help ur body absorb fat-soluble vitamins.
- fatty tissues cushion ur organs & provide ur body with insulation.
- there are several types of fat

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17
Q

Saturated Fats (5)

A

have only single bonds between carbon atoms in the fatty acids
- Each of these carbon atoms has the maximum number of hydrogen atoms, so the fat is called “saturated”
- Saturated fats= most animal fats like lard & butter
- Diets rich in saturated fats may promote fat deposit build-ups in blood vessel walls which can reduce blood flow & contribute to heart disease.
- Only a small percentage of ur daily intake of fats should be saturated fats

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18
Q

Unsaturated Fats

A

have at least one double bond in a fatty acid chain so we say it’s “unsaturated”
- found in fruits, vegetables, nuts, seeds, & fish
- Unsaturated fats like olive oil & sunflower seed oil, are usually liquids @ room temp
- Small amounts of unsaturated fats are an important part of a healthy diet

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19
Q

Trans Fats

A

AKA Hydrogenated fats
- they are unsaturated fats have been hydrogenated, meaning they have been processed to accept more hydrogen atoms
- they are solid @ room temp & have a longer shelf life than other unsaturated fats. –> Ex. margarine that is solid @ room temp is trans fat
- They are often used in frying fast foods
- they should be avoided as consuming trans fats as they contribute to heart disease & other health problems

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20
Q

Vitamins are

A

organic nutrients that u need in small amounts to regulate ur body processes & perform chemical reactions
- organic nutrients = nutrients that contain carbon
- if u picture carbs, proteins, & fats as building blocks, vitamins are the tools to help put them together.

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21
Q

What are the 2 types of vitamins?

A

water-soluble & fat-soluble
- water-soluble vitamins cannot be stored in ur body & should be included in ur everyday diet. Ex. vitamin C, the B vitamins
- small amounts of fat-solube vitamins can be stored in the fatty tissue of ur body for future use. Ex. Vitamins A, D, E, K

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22
Q

Minerals are

A

inorganic nutrients & do not contain carbon
- u need a variety of minerals in ur diet like calcium, iron, phosphorus, copper, sodium, & zinc to perform many different tasks. –> Ex. u use calcium to make bones & teeth.
- u need to consume mineral-rich foods each day to replace the minerals u lose in sweat, urine, & digestive waste

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23
Q

Vitamins & , minerals are found naturally in

A

many foods like meat, eggs, dairy products, whole-grain products, tofu, green leafy vegetables, & some fruit
- people who are not able to eat enough of a variety of foods from the basic groups sometimes take vitamin & mineral supplements
- however large doses of vitamin & mineral supplements may be harmful, so its important to read the recommended dose on labels & consult ur heath practitioner.se

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24
Q

Why is water the most important nutrient?

A
  • ur every cell needs water to complete its processes
  • many of the body’s chemical reactions take place in water
  • water makes up the bulk of blood,
    extra-cellular fluid, & other bodily fluids
  • many guides recommend 1litre of water daily–> more when ur physically active or its hot
  • without enough water to replace what u lose through sweat, urine, & respiration, u can suffer from dehydration, which leads to problems with many body systems
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25
Q

Converting food into energy

A
  • During cellular respiration, molecules like glucose make cellular energy by reacting with oxygen.
  • 40% of energy from food is converted into energy for performing cell functions
  • 60% is converted into thermal energy, radiating from ur body as heat –> heat generated by cellular respiration is not wasted: retaining some heat enables ur body to regulate its temp.
    –> when exercising, ur cells increase cellular respiration rate. That’s why u feel warm after exercising. —> ur body loses heat through sweating & other cooling methods.
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26
Q

When u sit in class, u radiate about as much heat as a ______ light bulb

A

100-W

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27
Q

A calorie is

A

the amount of energy required to raise the temp of 1g of water by 1 degrees Celsius.

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28
Q

Dietary Calories

A

calories u will learn about in this unit
- written with an uppercase C
- 1 dietary calorie = 1000 calories

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29
Q

Calories in fats, carbs, & protein

A

Fats are energy rich: 9 calories per gram
Carbs & proteins: 4 calories per gram
WHY?
- The carbon atoms in fats usually have more carbon-to-hydrogen bonds than carbon atoms in carbs or proteins. –> breaking these bonds releases a great deal of energy, so a 1g of fat releases more energy than 1g of protein or carbs

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30
Q

Female teenagers need ______ calories & male teenagers need ______ calories for the basic metabolic processes that sustain life plus energy for an active lifestyle.

A

2200, 2500

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31
Q

Daily physical activity of at least ____ minutes helps burn any excess calories & maintain a healthful weight. It also strengthens the _______, _______, & _________.

A

30, heart, bones, muscles

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32
Q

Nutrient Vs percentage of total daily calories recommended

A

Carbs: 45-65%
proteins: 10-30%
Fats: 25-35%

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33
Q

The science of nutrition is the study of …..

A

food & its effects on the body

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34
Q

Nutrition Labels

A
  • Health Canada requires that nutritional info be placed in a standardized manner on all packaged foods in order to identify the nutritional value –> they show nutrient contents & nutritional claims in a format that is easy to read & understand
  • reading them helps track daily requirements for important nutrients like dietary fibre, protein, vitamins, & healthy fats as well as unhealthy fats, sugar, & sodium that contribute to heart disease, high bp, & stroke
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35
Q

A nutraceutical is

A
  • is a substance that is purified from foods and taken like a medicine to provide health benefits including disease prevention. Ex. omega-3 fish oil pill that’s taken as a supplement
  • called nutraceuticals or functional foods is a new food industry that’s based on the idea that foods can be disease-fighters
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36
Q

Functional Food is

A

a food that has health benefits, including disease prevention, that are beyond the normal nutritional benefit of the food
- Fruit & veggies with high levels of vitamin A, C, E, & beta-carotene are identified as good candidates
- Orange juice: rich in calcium, Eggs: rich in omega-3, milk: rich in vitamin D
- Ex. Study by National Cancer Institute in the USA states that foods like garlic, cabbage, carrots, licorice, soy, & ginger as possible cancer-fighters.
- Ex. wheat bran can reduce risk of colon & breast cancer.
- rn Canada has 100s of companies in food industry & is becoming a world leader in such foods supply

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37
Q

Probiotics are

A

foods that contain substances that support health and that may help to strengthen the body’s natural defence against disease
- Probiotic products like probiotic yogurt, help increase beneficial bacteria back into the large intestine
- it is one of the fastest-growing areas of dietary products

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38
Q

The search to understand how our bodies digest food actually began ___________ of years ago

A

hundreds
- In 1700s, Lazzaro Spallanzani (natural history proff) devised a simple experiment to determine how food is broken down. –> subjects (humans & birds) swallowed a small sponge attached to a thread. after time, he pulled out the sponge to examine. –> He observed that the juice that filled the sponge could break down meat. –> concluded that an area in the body produced special juice that could digest food
- Spallanzani’s theory debunked the previously held theory that food was “cooked” in the heat of stomach and that’s how it is broken down.
- Scientists today, who use technology now, are “standing on the shoulders” of curious thinkers like Spallanzani who lived 100s of years ago

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39
Q

Industry experts expect that there will be continued growth in the “_________” food business

A

Designer
- the demand for food designed to fight disease will increase as consumers become more knowledgeable about health benefits of foods & rising health care cost

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40
Q

Canada’s Food Guide to Healthy Eating

A
  • It provides the public with needed info to make healthy food choices
  • Recommended servings on PAGE 283
  • According to the guide …
    1 serving of vegetables & fruit= medium fruit or 125mL vegetables
    1 serving of grain = 1/2 bagel, or small waffle
    1 serving of milk & alternatives = 200mL milk, or 200mL yogurt
    1 serving meat & alternatives = 30mL peanut butter or 75g chicken
  • Other guidelines in TABLE ON PAGE 283
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41
Q

To eat in a healthy way, you need to eat the _____ foods & the ____________ of different foods

A

right, right amount

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42
Q

What are the 4 stages of Food Processing? (just list them in order of occurrence)

A

1) Ingestion
2) Digestion
3) Absorption
4) Elimination

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43
Q

Stages of Food Processing: Ingestion

A
  • it’s the act of eating or drinking
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44
Q

Stages of Food Processing: Digestion

A
  • it’s the process of breaking food down into molecules that are small enough for the body to absorb
  • There are 2 types of digestion: Mechanical & Chemical
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45
Q

Mechanical Digestion

A

like chewing & churning of stomach, grinds food into smaller pieces, increasing it’s surface area (which makes chemical digestion easier)

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46
Q

Chemical Digestion

A
  • is breaking the chemical bonds within the large molecules of carbs, fats, & proteins into smaller molecules during hydrolysis
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47
Q

Hydrolysis is

A

a process that breaks bonds in food molecules by adding water to them in the presence of specific enzymes.

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48
Q

What is each Macronutrient broken down into?

A

Fat –> glycerol + fatty acids = used to build fats
Protein –> amino acids = used to build proteins
Carbs –> sugars (like glucose) = source of energy & source of chain of carbon atoms that ur body can used to construct other molecules containing carbon.

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49
Q

Stages of Food Processing: Absorption

A
  • It’s when cells absorb small molecules like amino acids and simple sugars in the small intestine.
  • from there, they enter the circulatory system where the molecules are transported in the blood to body cells, where they combine to make bigger molecules or are broken down to provide energy.
  • If there are more molecules then needed immediately, they are converted into fat for storage.
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50
Q

Stages of Food Processing: Elimination

A
  • It’s the process of removing from the digestive tract any undigested materials. –> these materials travel through the large intestine & are eliminated as feces.
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51
Q

In a digestive sac,…

A

food enters and wastes exit through the same opening
- Ex. a sea anemone has a digestive sac

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52
Q

An Alimentary Canal is

A

AKA gastrointestinal tract
a digestive tract with 2 openings, a mouth & an anus
–> Food enters through the mouth at one end and is churned & mixed as it travels along the tube. –> Further along, nutrients are absorbed from the digested food & then the wastes are disposed through the anus
- Alimentary canals are more efficient than digestive sacs for obtaining nutrients from food as it has more specialized regions for processing food.
- more complex animals have an alimentary canal

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53
Q

Alimentary Canal Length

A
  • The length of an animal’s alimentary canal is often correlated with diet.
    –> typically herbivores & omnivores have longer alimentary canals, relative to their body size, than omnivores –> this is cuz vegetation is harder to digest as it has cell walls. –> longer alimentary canal provides more time for digestion & more surface area of nutrient absorption.
  • In humans & many others, the alimentary canal is much longer than distance between mouth & anus. –> Ex. A person 1.8m tall can have a 9-m alimentary tract. It fits cuz portions with & loop back & forth
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54
Q

If the body is made out of the nutrients u digest, how do we prevent self-digestion?

A
  • by digesting food in specialized organs
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55
Q

6 main organs that make up the alimentary canal

A
  • mouth, pharynx, esophagus, stomach, small intestine, & large intestine
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56
Q

Accessory organs & glands of digestive system

A

include salivary glands, pancreas, liver, & gallbladder, which secrete digestive juices in the alimentary canal

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57
Q

6 Main Organs: Mouth

A
  • functions in ingestion & beginning of digestion
  • teeth & tongue = mechanical digestion
    –> tongue moves food towards teeth and down the throat
    –> Incisors, cuspids, & bicuspids cut into & tear food.
    –> molars grind & crush food into fine paste, making it easier to swallow & increases surface area for easier chemical digestion
  • the salivary glands secrete saliva for chemical digestion
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58
Q

6 Main Organs: Pharynx is

A

the upper portion of the throat. It’s a short tube shared by the digestive & respiratory system
- when u swallow, the epiglottis (a cartilage flap) temporarily seals off the airway & prevents the food from moving into the air passageway as it passes through the pharynx & into the esophagus.

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59
Q

In a typical day, salivary glands in your mouth secrete more than ___ of saliva

A

1L

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60
Q

Saliva is

A

a watery liquid that contains digestive enzymes, mucus, & other chemicals to chemically digest food in mouth
- Digestive enzymes in saliva include amylase, which breaks down chemical bonds in starches (a carb), like pasta & bread, to form sugars. –> that’s y if u chew on starchy food for long, it will taste sweet.
- Another enzyme, lysozyme, helps fight infection by digesting cell walls of bacteria that may enter the mouth.
- mucus (a sticky substance) in saliva, lubricates food so that it can slide down the tube without harming the tissues that line the tube.
- Chemicals in saliva neutralize certain acids in food, preventing teeth from decay
- saliva also moistens food & makes it easier to chew.

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61
Q

Bolus is

A

chewed clump of food

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62
Q

6 Main Organs: Esophagus is

A

a long, muscle-encased tube which connects the pharynx to the stomach
- Even though the esophagus is vertically oriented in the body, gravity plays no role in pushing the bolus down the esophagus –> instead, its pushed through peristalsis

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63
Q

Peristalsis

A

is the involuntary contraction and relaxation of longitudinal and circular muscles in a wave-like motion throughout the digestive tract, allowing for the propulsion of the food from the pharynx to the anus

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64
Q

a sphinctor is

A

a muscular valve that acts like a door.
- GOOGLE: A ring-shaped muscle that relaxes or tightens to open or close a passage or opening in the body

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65
Q

Heartburn

A
  • not related to heart
  • a sphincter at the end of the esophagus (cardiac sphinctor) closes to keep food from coming back up the stomach.
  • if this muscle opens at inappropriate times, like when u overeating, acid from the stomach can flow back into the esophagus, causing a burning sensation: heartburn
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66
Q

6 Main Organs: Stomach is

A

an elastic, muscular sac that continues the chemical & mechanical digestion of food.
- with accordion-like folds & highly elastic wall, ur stomach can stretch to hold up to 2L of food & drink, enough for ur body’s needs for many hours

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67
Q

Chemical Digestion in Stomach

A
  • bolus is bathed in gastric juice
  • HCI in gastric juice breaks apart the cells in food & kills bacteria swallowed with food
  • 1 gastric enzyme, pepsin, helps break large protein molecules into smaller molecules
  • Mucus lubricates & protects the stomach wall from the HCI, preventing stomach from eating itself.–> even with mucus, cells of stomach are eroded and every 3 days, enough new cells are generated to completely replace the stomach lining.
  • gastric glands don’t secrete gastric juice constantly. –> when u see, smell, or taste food, a brain signal is sent to ur stomach to stimulate the gastric glands to secrete gastric juice.
    –> ur gastric glands secrete up to 3L of gastric juice daily.
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68
Q

Mechanical Digestion in Stomach

A
  • about every 20 seconds, the stomach contents are mixed by churning of stomach wall. –> turns bolus into acid-rich liquid called chyme.
  • The muscles contract, creating churning motion that stirs the chyme & eventually forces it into small intestine –> flow of chyme into small intestine is regulated by a sphincter.
  • it typically takes 2-6 hours for the stomach to empty.
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69
Q

6 Main Organs: Small Intestine is

A

a long (6m), narrow (2.5 cm) tube where digestion is completed & absorption of most nutrients takes place.
- Digestion takes place in first portion, and absorption takes place along the rest of the length.
- peristalsis move chyme along the intestine, a journey that takes about 3-5 hours

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70
Q

Digestion in Small Intestine

A

first part of small intestine = duodenum
- fats are undigested till the duodenum cuz they are insoluble in water
So how do fats undergo hydrolysis?
- in duodenum, chyme mixes with several digestive juices like bile.
–> Although bile has no enzymes, it has substances that prepares fats for hydrolysis –> fats tend to clump together, making it difficult for enzymes to reach the molecules (less surface area). –> bile separates small fat droplets, which enables digestive enzymes to break down fats more efficiently
- Pancreatic juice contains enzymes that further break down carbs, proteins, & fats.
- Pancreatic enzymes, along with enzymes secreted by the lining of the small intestine, complete the chemical digestion of food.

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71
Q

Bile is

A

a yellow or greenish alkaline liquid produced by liver (body’s greatest internal organ)
- bile is stored in a sac-like structure called the gallbladder until it’s secreted into the duodenum

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72
Q

Pancreatic juice is

A

a clear alkaline liquid that neutralizes the acidic chyme & contains enzymes that further break down carbs, proteins, & fats.
- Pancreatic enzymes, along with enzymes secreted by the lining of the small intestine, complete the chemical digestion of food.

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73
Q

Absorption in Small Intestine

A
  • the small intestine is highly specialized for absorbing nutrients –> its wall is folded into many small finger-like projections called villi (singular villus). The cells lining each villus have microscopic projections called microvilli.
  • the villi increase the surface area of intestine, making absorption more efficient
  • at its core, each villus has a network of microscopic blood vessels & a small lymph vessel.
    –> once fatty acids & glycerol are absorbed, these building blocks are recombined into fats that are then transported into the lymph vessel.
    –> Sugar & amino acids are absorbed into bloodstream through blood vessels in each villus
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74
Q

Where does the nutrient-rich blood travel to once absorbed into bloodstream by the blood vessels in villi? (2)

A

-nutrient-rich blood from small intestine travels to liver, where many nutrients are converted into new substances like protein.
- The liver also modifies & detoxifies substances absorbed by the digestive tract before the blood carries these materials to the heart for distribution to the rest of the body.

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75
Q

6 Main Organs: Large Intestine is (6)

A

AKA colon
is a short (1.5m) wide (5cm) tube
- undigested food passes through a sphincter from the small intestine to this one.
- As material enters the large intestine, it passes by a small sac-like organ called appendix –> in some mammals, the appendix processes cellulose & other materials. –> In humans, the appendix contains white blood cells & plays a role in immunity.
- the large intestine absorbs any access water from this waste, making it more solid
- the wastes move along colon by peristalsis, taking about 12-24 hours

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76
Q

Water absorption in large intestine (3)

A
  • Saliva, gastric juice, & other digestive juices contain large amounts of water. –> together, about 7L of fluid are secreted into the alimentary canal each day –> some is absorbed with nutrients in small intestine
  • the large intestine absorbs most of the remaining water
  • together, the small & large intestine absorbs 90% of the water that enters the alimentary canal
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77
Q

Feces are

A

undigested food material and other waste products

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78
Q

the rectum is

A

the final portion of the large intestine/ colon

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79
Q

How is digestive waste removed from the body (2)

A
  • feces are stored in rectum until they can be eliminated.
  • 2 rectal sphincters, 1 voluntary & other involuntary, regulate the opening of the anus
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80
Q

Bacteria in colon produce …. (2)

A

important vitamins, including vitamin K & some B vitamins
- these vitamins are absorbed into the bloodstream from the colon.

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81
Q

Discomfort in digestive system can be caused by ….

A

eating too much, eating too quickly, or eating an inappropriate combination of foods

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82
Q

Gas in the digestive system is a result of… (2)

A

swallowed air or the breakdown of undigested food in colon
- Gas is made of odourless CO2, oxygen, hydrogen, & nitrogen –> when it’s passed through the rectum, it also includes small amounts of sulphur produced by bacteria there & the gas may smell unpleasant

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83
Q

Persistent or intensive discomfort in digestive system may be caused by….

A

inflammation, infection, malabsorption (difficulty in the digestion or absorption of nutrients from food), or another disorder

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84
Q

Endoscopy (3)

A

is when a narrow tube is inserted into the throat & passed into the esophagus, stomach, & upper intestine
- a small camera in the narrow tube enables the doctor to see the internal structures & to identify abnormalities
- sometimes the tube has tiny scissors that are used to cut a small piece of tissue for viewing under a microscope (biopsy)

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85
Q

A biopsy is (2)

A

Google: a procedure to remove a piece of tissue or a sample of cells from your body so that it can be tested in a laboratory.
- A biopsy is used to determine if the cells are normal & can also identify presence of Helicobacter pylori bacteria, which burrow into the stomach wall & cause inflammation.

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86
Q

Colonoscopy is (3)

A

when a thin, lighted tube with an attached camera is inserted through the rectum
- used to diagnose intestinal disorders, as it allows doctors to see further along the intestines
- if unusual growth is detected, the doctor may opt for a biopsy. –> if the biopsy indicates that the cells are abnormal or cancerous, it’s sometimes possible to surgically remove those cells during the diagnostic procedure

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87
Q

A less invasive diagnostic tool to examine digestive tract is… (2)

A

a procedure where the patient swallows a pill that contains a camera. Called “pill cam” or capsule endoscope
–> the pill proceeds through the intestines, it takes pics of the structures. –> the pill is later eliminated in feces/

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88
Q

Sum table on 295

A
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89
Q

The leading cause of death in Canadian adult men & women is _____________________

A

Cardiovascular Disease

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90
Q

Cardiovascular Disease is (2)

A

any disease that affects the heart & blood vessels.
- research shows that certain cardiovascular diseases cause changes to the lining of arteries, reducing the blood flow rate. –> when flow of blood in arteries is restricted, the cells cannot always obtain necessary nutrients efficiently & cell function is reduced or ceases.

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91
Q

“Laughter is the best medicine” (4)

A
  • stressful experiences can decrease the diameter of arteries, causing cardiovascular diseases
  • Scientists have investigated changes in the rate of blood flow in arteries before & after exposure to laughing. Also investigated the effects to joyful music.
    –> in both types of experiments, results showed an increase in arterial diameter
  • Essentially, including positive & joyful experiences in our daily lives could be good medicine
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92
Q

All the cells in an animal need to ___________________, _______________, & ______________________ (3)

A

gain nutrients, exchange gases, remove waste products
- some aquatic animals that have bodies only a few cells thick, transport materials across their cell membrane to & from their environment
- larger animals use an internal transport system to bring resources close enough to all cells for exchange of materials to occur
- Most animals have a CIRCULATORY SYSTEM that transports oxygen & carbon dioxide, distributes nutrients to cells, & removes cellular wastes.

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93
Q

Your cells need a constant supply of ___________ & ___________

A

nutrients, oxygen

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94
Q

The 3 primary components of the circulatory system are the __________, ___________, & _________________

A

blood, heart, blood vessels
- blood is pumped by the heart into the blood vessels

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95
Q

Open Circulatory Systems (3)

A

Many invertebrates have open circulatory system in which blood is NOT entirely contained within blood vessels.
- Ex, grasshoppers, molluscs, arthropods
- in these systems, a tubular heart (like a sline) pumps blood through vessels that open into spongy chambers called sinuses –> from sinuses, the blood bathes the body tissues, then collects in another set of sinuses & makes its way back to the heart!!!!

96
Q

Closed Circulatory Systems (4)

A
  • Earthworms, squids, octopuses, & vertebrates all have closed circulatory systems.
  • in this system, blood remains contained entirely within blood vessels that extend throughout the body
  • nutrients, oxygen, & waste move in and out through the thin walls of the smallest blood vessels
97
Q

In which system is blood circulated more efficiently : open or closed circulated system

A
  • Blood is circulated more efficiently in a closed circulatory system that an open circulatory system. –> cuz blood is completely contained within blood vessels can be pumped under higher pressure than blood in open-ended vessels.
98
Q

Cardiovascular System (4)

A
  • The closed circulatory system in humans & other vertebrates is sometimes called the cardiovascular system. (Greek kardia = heart, Latin vas= vessel)
  • our system has a network of 100, 000 km blood vessels (would encircle Earth two & half times)
  • supplies oxygen & nutrients, removes CO2 & other wastes in trillions of cells
  • it is very efficient –> normally it takes 1 minute for blood to make a complete circuit through ur body. –> increased activity like running, causes ur blood to circulate more quickly, keeping ur cells supplies with oxygen & nutrients.
99
Q

Blood is (4)

A

a highly specialized connective tissue–> part fluid (plasma) , part cellular (red & white blood cells, & platelets
- we have 4-6L of blood
- it transports oxygen, water, nutrients, and other chemicals to ur cells, and transports waste from tissues to areas where they can be removed
- it helps regulate body temp, fight infections, & heal wounds

100
Q

Plasma (5)

A

= 55% of blood volume
- straw-colored liquid
- it’s 90% water, which helps control body temp (google: When the body temperature increases, water from the plasma comes out as sweat from sweat glands. This reduces the body temperature)
- it is 10% is proteins, dissolved nutrients, & wastes like CO2
- Plasma proteins transport fatty acids & vitamins, & fight viral & bacterial infections

101
Q

Red Blood Cells are (6)

A

are cells that carry oxygen from the lungs to all tissues of the body
- a cellular component of blood
- remaining 45% of blood volume is MOSTLY red blood cells
- one cubic mm of blood contains 5 million red blood cells
- 1 red blood cell has about 250 million hemoglobin molecules. –> Oxygen molecules bind to iron part of hemoglobin molecule, giving blood the crimson colour
- once oxygen is released, red blood cells transport CO2 to lungs

102
Q

Hemoglobin is

A

a protein that binds oxygen in the lungs & releases it throughout the body

103
Q

Where are red blood cells reproduced?

A
  • in bone marrow at the rate of 2 million per second in a healthy adult
104
Q

Red blood cell Structure (5)

A
  • when they mature, they lose their nuclei & mitochondria –> gives them their shape: flat disk curving inwards in middle on top & bottom
    –> shape increases surface area for oxygen transfer compared to a spherical shape with same volume
    –> shape gives them flexibility so that they can pass through blood vessels of different shapes & sizes
  • Since adult red blood cells has no nucleus, it cannot replace its proteins, grow, or divide.
  • have a lifespan of a red blood cells of 100-120 days –> as they age, they become fragile & eventually break down. –> the iron from broken-down red blood cells is recycled in bone marrow where it becomes part of new blood cells
105
Q

White Blood Cells are (5)

A

cells that protect against infection, fight parasites, & attack bacteria.
- a cellular component of blood
- they do not have to stay with the blood vessels–> can move through vessel walls to attack foreign organisms
- usually, there are 4,000-11,000 white blood cells in 1 cubic mm of blood. –>dramatically increased when body has an infection
- Sometimes u notice pus forming at cuts. the pus= white blood cells + dead bacteria

106
Q

Similarity & difference between red & white blood cells

A
  • both are produced in bone marrow
  • white blood cells keep their nuclei (undergo mitosis) & can live for years
  • White blood cells are the ones responsible for Leukemia (blood cancer) as they are the only cells that have nucleus
107
Q

Platelets are (4)

A

cell fragment that originate when the cytoplasm of certain bone marrow cell divide –> the fragments, each enclosed in a cell membrane, break off & enter the blood
- a cellular component of blood
- 1 cubic mm of blood has 250,000-500,000 platelets
- the blood-clotting that stops blood flow upon injury is due to platelets–> platelets stick to the blood vessel damage site. –> they break apart & release substances called clotting factors. –> this makes nearby platelets sticky & activates a series of reaction among other clotting factors in the plasma, creating fibrin. –> within a few minutes this network of threads and cells builds up, eventually forming a patch that stretches over the torn tissue, forming a scab. This will protect the while new tissue grows.

108
Q

Fibrin is

A

a stand-like protein that threads trap red blood cells & platelets.

109
Q

How come some people’s wounds don’t clot normally with the use of platelets? (2)

A
  • some people have hemophilia, in which they do not have the necessary protein to form blood clots
  • their wounds bleed for longer than normal periods & they may need medical assistance to stop the flow.
110
Q

Blood Vessels are

A

tubes that form a pipeline within the body.
- Its walls are made up of smooth muscle tissue that regulates the diameter of the blood vessel, and connective tissue that enables the blood vessel to expand & contract as blood flows through it.
- Epithelial tissue lines the wall of all blood vessels.
- there are 3 types of bloods vessels: Arteries, Capillaries, & Veins

111
Q

Blood Vessels: Arteries are (5)

A

large blood vessels that carry blood from the heart to the tissues.
- the walls of arteries are made up of epithelial tissue wrapped in layers of smooth muscle & connective tissue
- the blood in arteries is under pressure due to the heart’s pumping action. –> the pressure ensures that the blood flows in one direction, towards the tissues.
- Arteries have thick walls because they need to withstand high pressure generated by the heart
- Further from the heart, the arteries branch into smaller & smaller vessels. –> the narrowest arteries (arterioles) flow into capillaries.

112
Q

Arterioles are

A

the narrowest arteries that flow into capillaries

113
Q

Blood Vessels: Capillaries are (4)

A

microscopic blood vessels with a high surface area resembling a network of tiny tubes
- Capillaries are used to by the circulatory system to have close contact with all the cells in the body to distribute nutrients & oxygen
- some capillaries are so narrow that only a few cells can travel through them at a time
- The walls of capillaries consist of a very thin layer of epithelial tissue encased in a moist membrane –> enables nutrients & oxygen to pass out of the blood, & waste products to pass into the blood.

114
Q

Blood Vessels: Veins are (5)

A

blood vessels that bring blood from the capillaries back to the heart.
- the walls of veins, like arteries, consist of epithelial tissue surrounded by smooth muscle & connective tissue –> however muscle layer in veins are thinner than arteries cuz the blood in veins is under very little pressure
- the main force that pushed blood though the veins comes from the skeletal muscle tissue where many veins are located. –> contracting these muscles squeezes the veins & forces blood through them.
–> most veins contain flaps of tissue (valves) that restrict blood flow to the heart only.
- small veins merge into larger ones

115
Q

How do nutrients pass from the blood vessels into the individual cells of ur body?

A

Process of diffusion: molecules move across a membrane from an area of higher concentration to an area of lower concentration

116
Q

The Diffusion Gradient is (2)

A

the gradual change in the concentration of solutes in a solutions as a function of the distance through a solution.
- other words: if the blood in a capillary has a higher concentration of oxygen than the fluid next to it, the oxygen moves spontaneously into the fluid by diffusion

117
Q

Where does the process of molecules diffusing out of the blood into the cells occur? (4)

A

the capillaries
- Capillaries are in close contact with body cells. –> no further than 10 micrometers from a capillary & the blood in it.
- critical to the main function of circulatory system: distribution of oxygen & nutrients, & removal of waste products

118
Q

Can molecules in the capillaries enter cells directly?

A

Nope –> body cells are surrounded by fluid, so molecules must enter fluid first, and then the cells.

119
Q

The exchange of small molecules between capillary & the fluid.

A
  • some small molecules (O2 or CO2), diffuse across cell membranes or pass through gaps between the epithelial cells of the capillary wall into the fluid. Ex. O2 diffuses from blood into fluid, & CO2 diffuses fluid into the blood.
120
Q

The exchange of large molecules between capillaries & the fluid.

A
  • Large molecules are sent into the fluid with the help of other transport processes like blood pressure.
  • blood pressure = the force blood exerts against artery walls.
    –> drives blood through the arteries, into the capillaries, & through the capillary walls.
  • once in the fluid, needed molecules move into the cells by diffusion
  • cell wastes move out of the cells into the fluid & eventually into the blood.
121
Q

The lymphatic system is

A

a network of vessels, nodes (connecting points), & organs that collects the fluid that leaves capillaries, “screens” it for microorganism, & returns it to the circulatory system.
–> when blood passes through capillaries, some of its components move through capillary walls & into the fluid between cells.
–> Daily, 3-4L of fluid leave the blood to surround ur cells.

122
Q

What is fluid collected by the lymphatic vessels called?

A

lymph –> it’s a clear, watery fluid made up of protein molecules, salt, glucose, & other substances
- it’s collected in a system of lymph vessels, where valves prevent lymph from flowing back towards capillaries
- the combination of muscle contractions squeezing the vessels & the one-way valves helps fluid move through the lymphatic system
–> lymph is drained into the circulatory system near heart.

123
Q

What would happen if lymphatic system did not drain lymph form the tissues

A

the lymph would accumulate, causing swelling called edema

124
Q

What is the spleen?

A

An organ that helps remove old or damaged blood cells, stores platelets, & helps control the amount of blood & blood cells that circulate through the body
- located in the upper left part of the abdomen under the ribcage.

125
Q

Some lymph vessels run alongside the small intestine to….

A

pick up fats & fat-soluble vitamins from the digestive tract & transports them into the bloodstream

126
Q

The lymphatic system also helps improve ____________

A

immunity
1)White blood cells mature in an organ called the thymus
2)Hundreds of lymph nodes (= small, bean-shaped enlargements) are scattered along lymph vessels throughout the body. –> filter out harmful micro-organisms & abnormal cells.

127
Q

When & who invented the stethoscope? (4)

A
  • In 1816, French doctor Rene Laennec (with accents) wanted to better diagnose his patients by hearing their heartbeat & other chest sounds.
  • He rmred that placing wood at ur ear, the sound was amplified, so he rolled a piece of paper (which is made of wood), placed on end on the patient’s chest and the other at his ear, and the sound was much clearer.
  • He invented the first stethoscope, which was later refined to what we have today
  • He wasn’t exactly correct as its not the wood that amplifies sound but the hollow tube that focuses & reflects the sounds
128
Q

Anatomy of the Heart (5)

A
  • size of clenched fist, its a hollow organ located between lungs & is almost entirely muscle.
  • structure of heart enables it to pump oxygen-poor blood to lungs & oxygen-rich to body.
  • the pericardium encloses the heart.
  • the mammal heart has 4 chambers: the right atrium, the right ventricle, the left atrium, & the left ventricle
  • valves in the heart prevent blood from flowing backwards
129
Q

Cardiac Cycle is

A

the entire process of pumping blood out and filling the heart with blood
- heart contracts=blood pumped out, heart relaxes= blood enters heart
- in average person, takes approximately 0.8 seconds

130
Q

The Pericardium is

A

a protective sac that enclosed the heart.
- its filled with fluid that lubricates the surfaces of the heart and the roots of the major blood vessels

131
Q

Artia are (3)

A

(singular, atrium)
the 2 upper heart chambers which receive blood returning to heart
- since they only pump blood the short distance to the ventricles, they have fairly thin walls

132
Q

Ventricles are (2)

A

the 2 lower heart chambers, which pump blood out of the heart to the body
- have thick muscular walls that enable them to pump blood throughout the body.

133
Q

Types of Heart Valves

A

1) valves between artia & ventricles= atrioventricular valves
2) valve between right ventricle & pulmonary artery= pulmonary valve (pulmonary comes from latin word for lung)
3) valve between left ventricle & aorta= aortic valve (aortic comes from greek word for “to lift”)

134
Q

What causes the “lub dub” sound of the heart? (2)

A
  • with each heartbeat, the valves open, allowing blood to flow through. –> Then they close preventing blood from flowing back
  • When the valves close, they cause the familiar heart sound of “lub dub”. –> the “lub” sound is the atrioventricular valves closing, while the “dub” sound happens when the pulmonary & aortic valves close
135
Q

What are the 2 circuits of blood flow

A
  • though it’s 1 organ, the heart acts like 2 pumps
  • 1 pump pushes blood into lungs and the pathway is called the pulmonary circuit
  • other pump pushes blood to rest of the body and the pathway is called the systematic circuit
  • this double pathway ensures that the oxygen-rich blood is constantly delivered to cells
136
Q

Pulmonary Circuit

A
  • In this circuit, blood travels from the right side of ur heart through the pulmonary arteries to ur lungs
  • in the lungs, blood picks up oxygen & releases CO2, which u then exhale
  • The pulmonary veins return the oxygen-rich blood to the left side of the heart
  • Most arteries in ur body carry oxygen-rich blood & most veins carry oxygen-depleted blood –> however, it’s the opposite in pulmonary circuit.
    –> pulmonary arteries carry oxygen-depleted blood to lungs & pulmonary veins carry oxygen-rich blood from lungs to heart
137
Q

Systematic Circuit (6)

A

In this circuit, oxygen-rich blood from lungs gathers in the left atrium & is then pumped to the left ventricle
- the blood is then pumped through the aorta, the artery that supplies oxygen-rich blood to all the systems of the body.
- From the aorta, oxygen-rich blood flows through the branching arteries to the capillaries. –> oxygen & other nutrients diffuse out of blood, & CO2 & other wastes diffuse in
- The now oxygen-depleted blood returns to right atrium through vena cava veins: superior vena cava & inferior vena cava (vena latin for vein & cava latin for cave or hollow)
- blood is pumped into right ventricle, which pumps it to the lungs through pulmonary arteries
- After being replenished with oxygen in the lungs, blood returns to heart through pulmonary veins & gathers in the left atrium.

138
Q

Coronary Arteries are (3)

A

a pair of arteries branching from the aorta that cover the surface of the heart like a crown and is used to supply the heart muscle cells with nutrients.
- they exist cuz heart recieves very little oxygen & nutrients for its cells from blood it pumps through its chambers
- In Latin, “coronary”= crowned

139
Q

The teenage heart beats over…

A

100, 000 times daily, on average 60-100 times per minute

140
Q

The rate at which ur heart pumps & the amount of blood that it pumps are affected by factors like…

A

age, fitness, & emotions
- Ex. Athletes may have heart rate lower than 60 (Exercise strengthens the heart muscle, enabling it to pump a greater volume of blood with each heartbeat. More oxygen gets delivered to the muscles, so the heart needs to beat fewer times than it would in a less-fit person while at rest)
- Ex. Children & babies usually have heart rates over 100

141
Q

A Pacemaker is

A

a specific region of heart muscle that sets the rate at which ur heart contracts
- located in wall of right atrium
- generates electrical impulses that rapidly spread over walls of both atria, making them contract
–> impulses then spread to heart region called the atrioventricular (AV) node.
–> from there, the electrical impulses spread to ventricles, causing them to contract, which sends blood to rest of the body.
- it ensure that the heart beats in rhythmic cycle: first atria contract, forcing blood to ventricles, which are relaxed. Then ventricles contract, forcing blood to arteries, while atria are relaxed. –> repeats at rate of 1 second during rest

142
Q

How is the pacemaker controlled?

A

-controlled by both nervous system & endocrine system (which creates hormones)
- 2 sets of opposing nerves control the pacemaker by speeding it up & by slowing it down
- Hormones, secreted into blood, also control the pacemaker. Ex. hormone epinephrine AKA adrenaline, increases the heart rate when body is under stressed.

143
Q

A Sphygmomanometer is

A

a pressure cuff used to measure blood pressure
- made in mm of mercury (mm Hg), a standard unit of liquid pressure
- the measurement is represented by 2 numbers separated with a slash like 120/70.
- the first # is called systolic pressure = highest recorded pressure in an artery when ventricles contract
- second # is Diastolic pressure= lowest recorded pressure in an artery during relaxation phase of the heartbeat

144
Q

What factors does blood pressure depend on?

A
  • depends on 2 factors
    1) Cardiac Output = the amount of blood is pumped by the heart each minute. Ex. if the volume of blood pumped through an artery increases, the blood pressure would also increase
    2) Resistance of Arteries AKA Arterial Resistance –> related to elasticity in the arteries. Ex. If the arteries do not expand easily & resist the flow of blood, the pressure on the arterial walls increases
145
Q

Blood pressure varies according to an individual’s….

A

height, weight, fitness level, as well as time of day, physical activity, hydration, & other factors.
- With age, blood pressure can increase
- smoking or high fat diets can increase blood pressure by causing arteries to become less elastic

146
Q

Blood pressure in healthy young adults

A
  • in healthy young adults, it varies between 110-130 over 70-90 with an average of 120/80
  • A blood pressure consistently about 140/90 is considered high
147
Q

What is an Exercise Stress Test?

A
  • test used to monitor the structure & function of circulatory system components including the heart, blood, & blood vessels.
  • patient performs exercise on a stationary bike or treadmill while hooked to an electrocardiograph that measures the electrical activity of the heart. –> heart rate, respiratory rates, blood pressure, & how tired the patients feels is also monitored
  • it helps diagnose coronary artery disease, determine a safe level of exercise, & predict risk of severe conditions like heart attacks.
148
Q

Plaque is (3)

A

a patchwork of cholesterol, calcium, & fat deposits sticking to the interior walls of arteries.
- plaque builds up throughout a person’s life –> thus, baby arteries have smooth clear surfaces
- Significant buildup of plaque can ultimately lead to cardiovascular disease.

149
Q

Atherosclerosis is (5)

A

a narrowing of the arteries resulting from plague building up inside the artery wall.
- as pathways narrow bp increases
- Sometimes the narrowing completely blocks blood flow, and if such blockage were to happen in one of the coronary arteries, the heart becomes deprived of O2 & nutrients.
- partial blockage cases= occasional chest pains called angina pectoris. –> treatment= angioplasty, where a small metal mesh tube is placed in artery, & it expands to artery from closing up
- severe blockage=blood clot could clos up artery, causing heart attack

150
Q

A Heart Attack is (5)

A

when the blood supply to the heart tissue is slowed or stopped usually due to narrowing coronary arteries cuz of atherosclerosis.
- During a heart attack, the heart usually doesn’t stop beating.
- symptoms include chest pain & upper body pain, that can be accompanied with shortness of breath & nausea
- if treatment is immediate, some of the heart muscle will die & be replaced by scar tissue.
- very rare in teens

151
Q

Arteriosclerosis is

A

an advanced stage of plaque buildup, which occurs when the deposits on the artery wall harden
- Arteries are flexible & can expand & contract, helping control bp –> with arteriosclerosis, the arteries lose their ability to stretch
–> this increases bp & the chance for blood clots to form within the blood vessels
- treatment includes heart bypass surgery, where a surgeon will take a vein or artery from another body part & use it to makes a detour around the blocked part of the coronary artery

152
Q

Sudden Cardiac Arrest is (4)

A

when the heart suddenly stops functioning, as from drowning, electrocution, trauma, or choking
- most common cause is coronary heart disease, where the coronary arteries become blocked
–> coronary blockages causes the heart to beat irregularly so that blood isn’t pumped efficiently & in a regular rhythm.
- if the heart rhythm is not reset immediately, like by a cardiac defibrillator, death will be within minutes

153
Q

Arrhythmia is (4)

A

a condition in which the heart beats irregularly, too quickly, or too slowly
- Most arrhythmia arises from problems with the electrical activity of the heart
- symptoms include dizziness, chest pain, & shortness of breath
- treatment to restore normal heartbeat includes implanting an artificial pacemaker or a small defibrillator under the skin of chest of abdomen

154
Q

Hypertension is (6)

A

AKA high bp
is when blood pressure is 140/90 or higher for an extended period of time –> which damages the heart & blood vessels
–> the heart must work harder to pump blood throughout the body, & over time, the heart muscles expand. –> if these muscles expand too much, they become weakened & can no longer push blood throughout the body.
- hypertension also exerts greater pressure on artery walls, causing small tears.
–> these tears can speed up atherosclerosis, which further increases bp
- teens can have high bp via genetic factors, excess body weight, diet, or lack of exercise.

155
Q

Heart Failure is (4)

A

a condition in which the heart can’t pump blood efficiently, cuz it can’t fill with enough blood or can’t send blood out to the body with enough force
- it’s a common condition, affecting both children & adults
- if diagnosed early, people with heart failure can live longer & lead more active lives by improving their lifestyle & following treatment plans
- in most severe cases, heart transplant may be necessary

156
Q

An aneurysm is (5)

A

a bulge in the wall of an artery.
- can be caused by injuries , genetic conditions, or disease
- as blood rushes through the artery, it further weakens the bulging wall & may burst through, causing serious internal bleeding
- can occur in any artery but usually in aorta branches.
- can be detected using Magnetic Resonance Imaging (MRI), a non-invasive imaging technology that produces 3d views of organs & tissues

157
Q

A stroke is

A

when a blood clot forms in an artery going to the brain.
- tissues downstream from the blockage can die from lack of O2.
- effects of strokes include partial paralysis, loss of speech, memory loss, & sometimes death. –> depend partially on location of brain where blockage occurred.

158
Q

List 5 controllable choices that promote Cardiovascular Health

A
  • Eat a healthy diet
  • Maintain a Healthy Weight
  • Exercise Regularly
  • Avoid Smoking & Second-hand Smoke
  • Get Regular Health Checkups
159
Q

5 controllable choices that promote Cardiovascular Health: Eat a healthy diet

A
  • Good choices for the heart include foods that are high in fibre & low in salt and LDL cholesterol.
  • Low-Density Lipoprotein (LDL) is found in foods high in saturated or trans fat like beef, butter, cheese, ice cream, deep-fried food, bakery food, margarines, & packaged snack foods
160
Q

Cholesterol is (5)

A

a fat that is a part of ur cell membranes & is used to synthesize hormones, bile, & vitamin D
- its made in liver, carried to tissue by blood.
- Cholesterol is transported by 2 types of lipoproteins= carriers made of fat & proteins
- High-Density Lipoprotein (HDL) is called “good cholesterol” cuz it helps remove excess cholesterol in tissues & arteries
- Low-Density Lipoprotein (LDL) is called “bad cholesterol” cuz it becomes part of the plaque in the arteries

161
Q

5 controllable choices that promote Cardiovascular Health: Maintain a healthy Weight (2)

A
  • avoid fat diets
  • consult a health practitioner for diet plans and a counsellors for coping strategies
162
Q

5 controllable choices that promote Cardiovascular Health: Exercise Regularly (2)

A
  • regular exercise reduces chances of condition that strain heart like high bp, high cholesterol, & diabetes
  • Aim for 40-60 minutes of moderately intense activities most days of week
163
Q

5 controllable choices that promote Cardiovascular Health: Avoid Smoking & Second-hand Smoke (3)

A
  • Tobacco smoke contains thousands of chemicals that can damage the tissues of ur heart & blood vessels
    1)Nicotine= a chemical found in tobacco smoke, narrows blood vessels & increases heart rate & bp
    2) the carbon monoxide in cigarette smoke replaces some oxygen in blood, forcing ur heart to work harder to supply enough oxygen
164
Q

5 controllable choices that promote Cardiovascular Health: Get Regular Health Checkups (1)

A
  • health practitioners can check ur bp, heart sounds, pulse rates, weight, & other indicators of ur health & track them from year to year –> can make suggestions early on to avoid issues later in life
165
Q

what cancer is currently the leading cause of cancer deaths globally?

A

lung cancer

166
Q

Why are traditional means of detecting cancer not the best?

A
  • X-rays & CT scans only detect the cancer once it is well developed
  • its really hard to detect cancer in early stages with this tech
167
Q

“Sniffing out” cancer in early stages (5)

A
  • over 3 weeks, a research team trained dogs to detect cancer by exposing them to cancer patients breath
  • healthy patients were used as experimental control
  • it had an accuracy between 88-97%
  • scientists found out that lung cancer cells produced unique chemicals that form gases that are expelled from the patients’ body in the breath which dogs could pick up on
  • this research can lead to developing tech to screen lung cancer simply using exhaled breath.
168
Q

Cellular respiration is…. (5)

A

a process that produces energy needed to fuel all cell activities
- it occurs in mitochondria.
- cells must have a constant O2 supply, & must constantly dispose of CO2
- if O2 isnt enough, energy isn’t produced efficiently, & cells ae harmed
- In order for cells to obtain enough O2, large volume of air must enter body –> about 21% of air= O2

169
Q

In animals with lungs, the transfer of gases from environment 2 the body & 2 the cells occurs in 3 phases: ____________, __________________, ______________________

A

breathing, transporting of gases, & exchange of gases in cells

170
Q

The respiratory surface is (2)

A

a very special membrane that gas exchange usually occurs in for multicellular organisms
- Although animals live in a wide variety of environments, the process of diffusion via the respiratory surface governs the function of their respiratory surface.

171
Q

A respiratory surface has certain characteristics to ensure that diffusion occurs efficiently which are….. (3)

A

1) A respiratory surface is a very thin & moist membrane that is permeable to the gases being diffused
2) The surface area of the membrane is large so as to maximize diffusion
3) A diffusion gradient must be maintained cuz diffusion moves gases from higher concentration to lower concentration –> other words: there must be a difference in concentrations of oxygen & CO2 on either side of the membrane surface. –> In most organisms, the circulatory system serves to transport gases to & from the membrane so that appropriate gas concentrations can be maintained

172
Q

Can animals use their entire body surface as a respiratory surface? (3)

A
  • Yes, ex. earthworms
  • Animals that breath through their skin are usually small or have flat bodies that give a high ratio of respiratory surface to body volume
  • Animals that breathe through their skin live in damp places or in water to keep their body surface moist.
173
Q

Gas Exchange in Aquatic Animals (4)

A
  • they live in water, thus respiratory surface is always moist
  • cuz source of useful gas is dissolved in water, an appropriate volume of water must come in close contact with thin respiratory membranes & yet not damage them
    –> hence, most have gills= folds in body surface specialized for gas exchange. Are extensions of body surface
  • gill design enables water to flows that gases diffuse from water & across respiratory membranes –> O2 diffuses directly into capillaries & CO2 diffuses out of capillaries & into the environment –> capillaries transport gases to and from gills to body cells
174
Q

Advantages & disadvantages that terrestrial animals that exchange gases by breathing air have compared to aquatic animals that exchange gases in water.

A

ADVANTAGES
1) There is a higher concentration of oxygen in air than water
2) Air is both lighter & easier to move than water
- terrestrial animals need to spend less energy than aquatic ones to exchange gases across respiratory surface

DISADVANTAGES
1) terrestrial animals lose moisture to their environment
- most terrestrial animals have evolved internal respiratory surfaces like tracheal systems & lungs to minimize loss of moisture.

175
Q

A tracheal system is

A

a system of tubes that extend through their bodies in many insects
- air enters & leaves system though openings in body surface
- larger tubes=tracheae branch into smaller & smaller tubes=tracheoles which extend to nearly every cell in the insect’s body
- gas exchange occurs along the moist membranes at the tips of the tracheoles

176
Q

Do insects need a circulatory system to exchange gases? (4)

A

No
- small insects can receive enough O2, & get rid of enough CO2 through diffusion across their membrane
- Larger insects pump in more air through rhythmic body movements that compress & expand the air
- their flight muscles help to rapidly pump air through tracheal systems –> thus insects consume much more O2 when they fly

177
Q

Lungs are (4)

A

internal, thin-walled sacs with large surface area that is the site of gas exchange in birds, mammals, reptiles, & some amphibians
- Human lungs: right=3 lobes, left= 2 lobes cuz of heart
- in lungs O2 diffuses into blood & is transported through blood vessels to body cells.
- CO2 diffuses out of blood, enters lungs, & moved out of body through breathing
- Aquatic reptile & mammals that breath air must hold their breath under water

178
Q

The structures of the human respiratory system in order include….

A

the mouth, the nose (same level in order), pharynx, larynx, trachea, & lungs,
- work together to move gases in & out of body

179
Q

Gas Journey to lungs: step 1 (3)

A

As u inhale, air enters respiratory system.
- many air impurities in air like dirt & bacteria, are filtered by hair & mucus in ur nose.
- Air is warmed & moisture is added

180
Q

Gas Journey to lungs: step 2 (2)

A

Air passes into pharynx, where passageways for air & food cross.
- pharynx is always open unless when u eat (rmr epiglottis)

181
Q

Gas Journey to lungs: step 3 (3)

A
  • From pharynx, air goes to larynx (voice box)–> the 2 vocal cords in larynx vibrate, producing sound
  • then air enters trachea (windpipe) –> C-shaped rings of cartilage maintain tubular shape of trachea.
  • the trachea splits into 2 bronchi (singular= bronchus), which are air tubes that connect the trachea to lungs
182
Q

Gas Journey to lungs: step 4 (3)

A
  • in each lung, the bronchus repeatedly branches into finer & finer tubes = bronchioles
  • bronchi & bronchioles are surrounded by smooth muscle.
    –> as muscles contract or relax, they control size of airways
183
Q

Gas Journey to lungs: step 5 (2)

A
  • Each bronchiole ends in grapelike clusters of tiny air sacs called alveoli (singular=alveolus)
  • ur cells contains millions of these tiny air sacs, which provide a very larger surface area for gas exchange
184
Q

why are alveoli suitable for gas exchange? (3)

A

1) they have thin walls
2) great surface area
3) have direct contact with capillaries

185
Q

Respiratory System Lining (3)

A
  • from ur nose & mouth all the way to ur lungs, is lined with moist epithelial tissue.
  • In trachea & bronchi, epithelial cells are lined covered in cilia & , a fine layer of mucus.
    –> the mucus traps foreign particles & removes them from the air, purifying it. –> the cilia then sweep mucus-trapped particles up towards pharynx where they can be coughed out or swallowed.
186
Q

Breathing is (3)

A

AKA ventilation
the process of moving air into & out of ur lungs
- on average u breathe about 15 times/min or more than 21,000 breaths daily

187
Q

What is the size of ur lungs? (3)

A

about size of football each
- together have a total capacity of 6L but u only use 0.6 L of the volume in normal breath.
- when exercising vigorously, u can use up to about 20x the oxygen u use at rest

188
Q

The process of ventilation is a largely a __________ process.

A

passive
- meaning the process works without ur attention & without using extra energy

189
Q

what 2 structures change the volume & thus the air pressure of the chest cavity during process of breathing? (3)

A

Diaphragm & Rib Muscles
- Inhale= diaphragm & rib muscles contract.–> inhalation expands chest cavity, increasing volume of lungs, resulting in reduced air pressure within the alveoli. –> since air moves from high pressure areas to low pressure areas, air rushes in through ur nose or mouth & fills the alveoli
- When diaphragm & rib muscles relax, ur lung volume decreases, causing higher air pressure in the alveoli. Air rushes from ur lungs out through ur nose or mouth as u exhale

190
Q

Gas Exchange in Lungs (5)

A
  • the inner surface of each alveolus is lined with a layer moist epithelial cells
  • O2 inhaled dissolves in the film of moisture on these epithelial cells
  • The oxygen then diffuses into a web of capillaries surrounded each alveolus & enters red blood cells, binding to hemoglobin –> hemoglobin increases the efficiency of gas exchange by creating diffusion gradient. Other words, when the hemoglobin in a red blood cell binds to O2, it removes oxygen from the plasma.
  • oxygen then keeps on diffusing from the alveolus into the plasma cuz the O2 concentration is lower in the alveolus
  • By binding oxygen, the hemoglobin actually increases the blood’s ability to transport oxygen about 60x
191
Q

Transporting O2 & CO2

A
  • ur cells access O2 they need from nearby blood vessels
  • As cellular respiration produces energy, CO2 is produced as a by-product of that process
  • CO2 diffuses the opposite way to oxygen, from the capillaries across the epithelial cells & into the alveoli
  • The CO2 is carried away from the cells & deposited in the lungs –> then CO2 is expelled back up the trachea, through the nose or mouth, & into the environment
192
Q

Breathing is controlled by the________________

A

medulla oblongata–> a part of the brain located near the top of the spinal cord
–> it sends nerve signals to the diaphragm & rib muscles, causing them to contract & relax

193
Q

What controls the breathing rate?

A
  • surprisingly, it is usually the level of CO2 that controls breathing rate –> When CO2 dissolves in a solution containing water, it forms Carbonic acid (H2CO3)
  • CO2 diffuses through a capillary wall, most of it dissolves in the plasma
  • Ex. when u exercise heavily, cell metabolism increases carbon dioxide output. This causes more CO2 to dissolve in the plasma. The increased CO2 dissolved in the plasma slightly lowers the pH of the plasma (more H+ ions). A drop in pH level causes the brain to send nerve impulses that increase breathing rate. As a result, more CO2 is exhaled, & the pH returns to normal, a state called homeostasis
194
Q

Homeostasis is

A

the state of internal stability maintained by the body

195
Q

__________________ is one of the best things u can do for ur respiratory health. (4)

A

Regular exercise
- helps strengthen all body muscles including heart & diaphragm.
- vigorous activities like swimming & skiing increase ur lung capacity & help ur body use O2 more effectively.
- Inactivity & a sedentary lifestyle decrease ur ability to exchange O2 for CO2

196
Q

A sedentary lifestyle is

A

one that lacks enough vigorous physical activity.

197
Q

The structures & function of the respiratory system can be altered by….. (2)

A

disease or exposure to viruses or environmental pollutants
- Ex. environmental pollutants can trigger respiratory allergies like hay & fever, & cause the tissues in the airways to swell

198
Q

Common Cold & Respiratory System

A
  • common cold is a group of symptoms like coughing, sneezing, & a sore throat
  • can be caused by number of viruses that pass through the protective lining of nose & throat
  • sometimes accompanied by sinusitis
199
Q

Sinusitis is (4)

A

a condition caused by viruses or bacteria in which the sinuses become swollen & irritated
- Sinuses=moist air spaces around the nose –> when they become inflamed, u may notice change in voice
- Includes a stuffy or runny nose, pain or swelling around eyes & cheekbones, & a feeling of pressure in the head
- Dry air, lack of sleep, allergies, stress, second-hand smoke, & not eating properly all lower resistance to cold & sinusitis

200
Q

Influenza is (5)

A

AKA flu
is a common viral infection of the upper respiratory system
- it’s spread by airborne droplets & contact with contaminated objects
- can cause more serious respiratory illnesses, especially in elderly, infants, & people with heart & lung disease
- Ex. it can develop into pneumonia

201
Q

Pneumonia is

A

a serious infection of the lungs
- the alveoli in the lungs fill with fluid, which prevents O2 from reaching the blood
- can be caused by a variety of viruses, bacteria, fungi, & parasites

202
Q

Asthma is (5)

A

a chronic disorder of the respiratory system in which airways become narrowed.
- smooth muscles surrounding the bronchi & bronchioles contract, narrowing the airway, making breathing very difficult –> makes it fatal
- can be caused by exposure to airborne pollutants, cold air, cigarette smoke, some drugs, & respiratory infections
- usually, a doctor may prescribe use of puffer to improve breathing
–> it administers a regulated amount of bronchodilator= drug that causes narrow airways to expand

203
Q

Bronchitis is (4)

A

a condition in which the bronchioles & the trachea become irritated or infected, causing them to swell & produce excess mucus
- excess mucus causes frequent coughing & difficulty breathing
- It may become chronic, or long-lasting, when person exposed to cigarette smoke or other harmful pollutants –> the swollen airways & excess mucus may last for months or years
- Heart must work harder to transport an adequate amount of O2 through the body

204
Q

Emphysema is (7)

A
  • comes from Greek word meaning to puff up
  • Emphysema means over-inflated lungs–> Google: it’s characterized by abnormal permanent enlargement of lung air spaces
  • occurs when the cilia lining the airways become damaged.
    –> cuz the cilia no longer filter & channel particles, the bronchioles become clogged & less air reaches the alveoli
    –> Air pressure builds up–> lungs appear inflated
    –> pressure eventually tears alveoli walls & some cells become oxygen deprived, causing heart & breath rat to increase
    –> body becomes stressed fatigued from spending more & more energy breathing
  • causes include smoking & longtime exposure to workplace chemical hazards like working in underground mines
205
Q

Chronic Obstructive Pulmonary Disease is (5)

A

AKA COPD
a serious condition that occurs when chronic bronchitis & emphysema are found together
- affected people may need external O2 source like a canister connected to nostrils
- Meds like bronchodilators can be used to reduce inflammation & improve the airflow
- if untreated, could lead to respiratory failure

206
Q

Cystic Fibrosis is (8)

A

a fatal genetic disease where abnormally thick mucus blocks airways
- the mucus traps bacteria in lungs & leads to infection that damages lung tissue.
- the mucus is very hard to dislodge, making breathing difficult
- must participate in daily physical therapy to ease the flow of air.
- affects may systems including the respiratory & digestive
- Recent estimate: 1 in 3600 Canadian children are born with it
- In 1989, Lap-Chee-Tsui (geneticist @ UFT) identified the gene for it
- research for cure is ongoing

207
Q

SARS is (7)

A

AKA Severe Acute Respiratory Syndrome
a serious pneumonia-like respiratory disease that is caused by type of coronavirus
- the virus is spread through sneezing or coughing
- causes an unusual lung inflammation, fever, & cough
- breathing becomes very difficult & hospitalization may be necessary
- some cases= fatal
- 1st case= Nov 22, China. –> by the time it ran its course in July 2003, it had spread in 37 countries & caused about 800 global deaths

208
Q

SARS in Canada (4)

A
  • all cases= Ontario
  • Doctors Sheela Basrur, Collin D’Cunha, James Young & others helped install infection control procedures
  • April 2003, Vancouver & Winnipeg scientists mapped genetic sequence of virus linked to SARS, important step to fighting the disease
  • SARS spread has been contained, but may still be present in animal populations & could return to human population
209
Q

Lung Cancer is (4)

A

a disease that starts when lung cells begin to behave abnormally by growing too fast & grouping together in abnormal ways
- tumour= group of cancer cells
- victims may develop recurring lung infections, chronic coughs, or difficulty breathing
- 85% lung cancers are linked to smoking

210
Q

Lung Cancer treatment (3)

A
  • there are 2 types of lung cancer & their treatments differ
  • some cases, surgery is used to remove lung tumours –> amount of lung tissue removed varies from a small wedge to an entire lung
  • drugs or different types of radiation may also be used to try to destroy the cancer cells
211
Q

Respirometer usage usage in respiratory conditions (2)

A
  • doctors use them to measure a patient’s breathing movements & lung capacity
  • blood & mucus samples are observed so abnormalities are identified
212
Q

Ultrasound, X-ray, CT scan, & MRI scan usage in respiratory conditions (1)

A
  • after observing ur nose & throat, doctor may order a Ultrasound, X-ray, CT scan, or MRI scan to reveal the size & shape of airways & abnormality presence like tumours
213
Q

Florescent dyes & two-photon imaging microscope usage in respiratory conditions (1)

A
  • with these tools, researchers can investigate molecular structure of individual cells of the respiratory systems like that of lung cancer cells
214
Q

Endoscope usage in respiratory conditions (2)

A
  • used to remove obstruction in nasal passages
  • if problem source is in trachea or lungs, a endoscope called a bronchoscope may be inserted through nose or throat & passed into the lungs
215
Q

Laser usage in respiratory conditions (1)

A
  • info from imaging tech may call for surgery, & lasers can be used to destroy obstructions during surgery
216
Q

Lung Transplant usage in respiratory conditions (2)

A
  • considered when all other treatments fail
  • if lung damage is severe like in cystic fibrosis, a double lung transplant may be recommended
217
Q

Your _____________, _______________, & _____________ are closely connected in their structures & functions

A

Respiratory, circulatory, digestive
- a problem in any one of these systems affects function of others & ur overall health

218
Q

What are 4 conditions that effect the respiratory, circulatory, & digestive systems?

A

1) Tuberculosis
2) Heart Failure
3) Smoking
4) Diabetes

219
Q

How does tuberculosis affect ur respiratory, circulatory, & digestive system (4)

A

-tuberculosis=bacterial infection that’s spread when an infected person coughs or sneezes, releasing the bacteria into the environment
- the bacteria usually target lungs.–> respiratory system
- once in lungs, the bacteria sometimes crosses through the alveoli into the bloodstream –> Circulatory system
- the blood then transports the bacteria to other tissues & organs, infecting them too. –> digestive system

220
Q

How does Heart Failure affect ur respiratory, circulatory, & digestive system (4)

A
  • it’s primarily a circulatory system problem
  • it can result in reduced nutrient transportation to cells, affecting digestive system
  • can result in leakage of fluid from capillaries in the lungs to the alveoli, causing respiratory problems
221
Q

Smoking (6)

A
  • Cigarette smoke basically consists of microscopic carbon particles that are coating with toxic chemicals
  • toxic substances in tobacco smoke irritate the cells lining the bronchi & destroy the cilia.
    –> Without cilia, these cells lose their ability to move particles out of the respiratory system
  • smoker must cough frequently to try to clear the mucus that is no longer moved by the cilia
    –> when they lose the ability to remove these harmful particles from the lungs, smokers are at a greater risk for diseases caused by these particles
  • adding to cigarette smoke toxins, damage to respiratory system increases risk of damage from air pollution, dust, & airborne bacteria
222
Q

Smoking & Cancer (4)

A
  • chemicals in cigarette smoke cause cancer
  • smokers=85% of all lung cancer cases
  • smokers have increases risk for cancer of gallbladder, pancreas, mouth, & throat –> connection to digestive system
  • women who smoke during pregnancy are more likely to babies born prematurely and/or with lower birth weight
223
Q

Smoking & Cardiovascular disease (4)

A
  • after cancer, cardiovascular disease=2nd highest death cause in smokers
  • smoking raises bp & cholesterol levels in blood
  • smoking damage to respiratory system makes heart to work harder to deliver enough O2 to cells
    –> smokers have higher heart attack & stroke rate.
224
Q

Affects of second-hand smoking (3)

A
  • some cigarette smoke toxin are in greater concentration in second-hand smoke,
  • it too can cause cancer
  • Children of smokers have a higher risk of developing colds, asthma, & allergies, & have more frequent hospitalizations for bronchitis & pneumonia
225
Q

Benefits by stopping smoking (2)

A
  • huge health benefits no matter age or how long person has been smoking
  • after 10-15 years of not smoking, chances of lung cancer & heart disease return to normal
226
Q

Rather than viewing a problem as if it affected only 1 organ or organ system, doctors consider the health problem in the context of _______________________in the body

A

interacting systems
- this approach to diagnosis & treatment of health problems has led to development of many new products & technologies

227
Q

Example of need to view a condition & its treatment holistically is ____________

A

diabetes

228
Q

Diabetes is

A

a group of diseases in which high levels of blood glucose result from a problem in insulin secretion, insulin action, or both.

229
Q

Insulin is (6)

A

a chemical produced by pancreas that controls the level of blood glucose
- discovered by Canadians: Frederick Banting & Charles Best, in 1921
- If it isn’t present or functioning properly, glucose builds up in blood & can’t be used by cells for energy.
—> diabetes patients may suffer from fatigue cuz the sugar that is usually used to make energy by cellular respiration is not available to cells but remains in blood
- over time, high blood glucose can result in serious health issues like blindness, kidney problems, & heart disease
- high blood glucose can damage coronary arteries by increasing artery plague –> can lead to atherosclerosis, which can increase bp

230
Q

Type 1 Diabetes (4)

A
  • pancreas cells are damaged & thus can’t produce insulin
  • exact cause isn’t understood
  • although several genes are associated with onset of this disease, appears that cellular environment also play a role in its development
  • rn Type 1 diabetes can’t be prevented, but effects can be controlled.
231
Q

Type 2 Diabetes (4)

A
  • in this type, the body cells don’t respond to insulin appropriately
  • Type 2 diabetes cases are increasing dramatically
    –> reasons 4 this increase including rising obesity rates & the increasingly sedentary lifestyle of Canadians –> recent research= 29% Canadians watch TV for 15 or + hours/week, 15% Canadians report using computer for 11 or + hours/week for leisure. –> This sedentary lifestyle increases extra weight
  • excess body fat seems to interfere with the body’s ability to use insulin effectively
232
Q

Diabetes Treatment (5)

A
  • patients must have their insulin replaced, usually through daily injections
  • to administer correct amount, diabetics test their blood sugar via blood tests
  • physical activity, nutrition, & emotional state all effect blood sugar levels, & so insulin must be administered accurately
  • patients must make careful choices of physical activities & foods to control blood sugar levels
  • planning & timing of meals is also important in maintaining levels
233
Q

Genetic tech & Diabetes (4)

A
  • enabled doctors to identify genes that seem to control the body’s response to diabetic meds
    –> more personalized approach can occur
  • experimental treatment for Type 1 diabetes includes transplanting cells from donor pancreas to patient’s to produce insulin
  • possibly, we can deliver the insulin gene into cells lining small intestine using nanoparticles–> by adding the gene to intestinal cells, the cells can be reprogrammed to produce insulin needed
234
Q

Tech innovations & diabetes (3)

A
  • imaging tech like MRI & CT scans enable docs to view internal organs in 3d
  • in recent years, NASA imaging tech used to view landforms from space have been used to analyze pancreas images
  • sophistication of imaging tech has increased but availability outside urban centres is still a challenge
235
Q

Research shows that a healthy & active lifestyle can reduce the risk of Type 2 diabetes by_____.

A

50%
- exercise can improver overall health levels by increasing blood flow to cells, normalizing bp, & reducing blood glucose levels.