Chapter 1: Structure and Function of Body Systems Flashcards

1
Q

Describe the axial skeleton.

A

Skull (cranium)
Vertebral column (C1 through coccyx)
Sternum
Rib cage

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2
Q

Describe the appendicular skeleton.

A

Shoulder (pectoral girdle): scapulae, clavicles
Arm and wrist bones: humerus, radius, ulna, carpals, metacarpals, phalanges
Pelvic girdle (coxal or innominate bones)
Leg and ankle bones: femur, patella, fibula, tibia, tarsals, metatarsals, phalanges

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3
Q

Joints

A

Articulations between bones

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4
Q

Fibrous joints

A

Joints that allow no movement (e.g. sutures of the skull)

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5
Q

Cartilaginous joints

A

Joints that allow for limited movement (e.g. intervertebral disks)

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6
Q

Synovial joints

A

Joints that allow for considerable movement (e.g. elbow, knee)

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7
Q

Hyaline cartilage

A

Cartilage that covers articulating bone ends

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8
Q

Synovial fliud

A

Viscous fluid that lubricates a joint

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9
Q

Uniaxial joints

A

Joints that rotate around a single axis (e.g. elbow)

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10
Q

Biaxial joints

A

Joints that rotate around two perpendicular axes (e.g. wrist, ankle)

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11
Q

Multiaxial

A

Joints that rotate around all three perpendicular axes that define space (e.g. ball-and-socket joints - hip, shoulder)

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12
Q

Vertebral column

A

Cervical spine: C1-C7
Thoracic spine: T1-T12
Lumbar spine: L1-L5
Sacral spine: S1-S5 (fused together, form rear of pelvis)
+ 3-5 coccygeal vertebrae

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13
Q

Epimysium

A

sheath of connective tissue surrounding the outside of a muscle

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14
Q

Perimysium

A

sheath of connective tissue surrounding a bundle of muscle fibers

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15
Q

Endomysium

A

sheath of connective tissue surrounding a single muscle fiber

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16
Q

Tendon

A

Strong, fibrous connective tissues that attaches muscle to bone

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17
Q

Bone periosteum

A

Connective tissue that covers all bones, except at the surface of the joints

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18
Q

Proximal

A

Denotes a limb muscle attachment closer the the trunk

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19
Q

Distal

A

Denotes a limb muscle attachment further from the trunk

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20
Q

Superior

A

Denotes a trunk muscle attachment closer to the head

21
Q

Inferior

A

Denotes a trunk muscle attachment further from the head

22
Q

Muscle fiber

A

Muscle cells; long and cylindrical with a diameter similar to that of a human hair (50-100 micrometers); multinucleate with striated appearance under magnification

23
Q

Fasciculi

A

A bundle of muscle fibers

24
Q

Sarcolemma

A

Membrane of a muscle cell

25
Q

Motor neuron

A

Nerve cell

26
Q

Neuromuscular junction

A

The junction between a motor neuron and the muscle fiber(s) it innervates

27
Q

Motor unit

A

Motor neuron + muscle fiber(s) it innervates

28
Q

Sarcoplasm

A

Cytoplasm of a muscle fiber

29
Q

Myofibrils

A

Bundles of contractile protein filaments (actin and myosin)

30
Q

Myosin

A

Thick filaments; globular head + hinge point + tail fibrous tail

31
Q

Actin

A

Thin filaments; two strands arranged in a double helix

32
Q

Crossbridge

A
33
Q

Sarcomere

A

The smallest contractile unit of skeletal muscle

34
Q

A-band

A

Area in the center of the sarcomere where myosin and actin overlap; length never changes length during contraction

35
Q

I-band

A

Actin only; shortens during contraction

36
Q

H-zone

A

Myosin only; shortens during contraction

37
Q

M-line

A

Center of the sarcomere (and center of the A-band) and attachment site for myosin

38
Q

Z-line

A

Defines the boundary of a sarcomere; bisects the I-band of neighboring sarcomeres

39
Q

Sarcoplasmic reticulum

A

Specialized endoplasmic reticulum in muscle cells dedicated to storage of calcium

40
Q

T-tubules

A

Invaginations in the sarcoplasmic reticulum that conduct impulses (action potentials) from the sarcolemma deeper into the cell

41
Q

Action potential

A

An electrical nerve impulse that signals the release of calcium from the sarcoplasmic reticulum into the myofibril and causes tension development in a muscle

42
Q

Sliding filament theory

A

Actin filaments at each end of the sarcomere slide inward on myosin filaments, pulling the Z-lines closer to the center of the sarcomere and shortening the muscle fiber

43
Q

Troponin

A
44
Q

Tropomyosin

A
45
Q

Power stroke

A
46
Q

Explain the steps of muscle contraction

A
  1. Action potential travels from the motor neuron via neurotransmitter acetylcholine, which stimulates the release of calcium into the myofibril once it reaches the muscle.
  2. Calcium binds to troponin, which causes tropomyosin to shift and expose protein-binding sites on actin filaments.
  3. Myosin binds to actin to form a cross-bridge.
  4. ATP on myosin is broken down via ATPase into ADP and phosphate, which provides energy for the power stroke (pulling action). Sarcomeres are shortened (I-band and H-zone)
  5. Another molecule of ATP replaces ADP on myosin cross-bridge globular head, which detaches from active actin site and returns to its original position.
  6. Stimulation of motor neuron stops, calcium is pumped back into the SR, and actin and myosin return to unbound sites.
47
Q

Acetylcholine

A

Neurotransmitter that diffuses across the neuromuscular junction and causes excitation of the sarcolemma

48
Q

All-or-none principle

A

All muscle fibers in the motor unit contract and develop force at the same time. It’s all or none!

49
Q

Twitch

A