Chapter 1. Overview of stroke and TIA Flashcards

1
Q

Age standardized mortality of stroke

A

82.5/100,000

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2
Q

Ranking of stroke in specific disease with greatest burden

A

5th

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3
Q

WHO definition of stroke

A

Neurological deficit of cerebrovascular cause beyond 24 hours or interrupted by death in 24 hours

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4
Q

TIA definition

A

Transient episode of neurological dysfunction caused by focal brain, SC, or retinal ischemia without infarction, that typically last less than an hour

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5
Q

Documented CNS infarction that is asymptomatic but without history of acute neurological dysfunction attributed to lesion

A

Silent CNS infarction

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6
Q

Distribution of subtypes of stroke in western data

A

80% ischemia

20% hemorrhagic

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7
Q

Age standardized death rate of stroke in the Philippines

A
  1. 84/100,000 ICH
  2. 72/100,000 ischemia

ICH > Ischmia

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8
Q

Phases of stroke based on onset

A

Hyperacute: 0-6 hours
Acute: 6-72 hours
Subacute: 3 days - 3 weeks
Chronic: > 3 weeks

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9
Q

This classification is based on clinical syndrome or combination of CT-Scan findings

A

Oxfordshire Classification

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10
Q

Disadvantage of utilization of oxfordshire

A

Poor in discriminating between lacunar and small volume infarction

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11
Q

Posterior circulation syndrome is defined as presence of

A

Isolated homonymous
Brainstem
Cerebellum

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12
Q

In 10 Asian countries using Oxford shire what is the most common syndrome

A

PACI 27%
LACI 25%
TACI 12%
POCI 10%

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13
Q

This classification is based on pathophysiology using advance diagnostics

A

TOAST classifcation

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14
Q

What is the other purpose of TOAST classification

A

Purpose of investigating the efficacy of anticoagulation

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15
Q

Large artery atherosclerosis is defined as

A

> 50% significant stenosis
Ulcerated plaque >2mm thick
1.5cm subcortical and subcortical infarct
Absence of cardioembolism

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16
Q

Extracranial carotid atherosclerosis prevalence in local study

A

4%

17
Q

Intracranial Carotid stenosis prevalence in local study

A

26%

18
Q

Event rate of recurrent vascular events in intracranial stenosis

A

15%

19
Q

Stroke risk in patient with TIA

A

2 days - 3.1%
7 days - 5.2%
30 days - 8.0%
90 days - 9.2%

20
Q

Neurologic differential diagnosis for TIA

A

Migraine with Aura

Focal Encephalitis

21
Q

Differential diagnosis of Amaurosis Fugax

A
Malignant Hypertension
Acute Glaucoma
Intracranial Hypertension
Central retinal vein thrombosis
Retrobulbar neuritis
Retinal Detachment
Temporal Arteritis