Chapter 1. Overview of stroke and TIA Flashcards
Age standardized mortality of stroke
82.5/100,000
Ranking of stroke in specific disease with greatest burden
5th
WHO definition of stroke
Neurological deficit of cerebrovascular cause beyond 24 hours or interrupted by death in 24 hours
TIA definition
Transient episode of neurological dysfunction caused by focal brain, SC, or retinal ischemia without infarction, that typically last less than an hour
Documented CNS infarction that is asymptomatic but without history of acute neurological dysfunction attributed to lesion
Silent CNS infarction
Distribution of subtypes of stroke in western data
80% ischemia
20% hemorrhagic
Age standardized death rate of stroke in the Philippines
- 84/100,000 ICH
- 72/100,000 ischemia
ICH > Ischmia
Phases of stroke based on onset
Hyperacute: 0-6 hours
Acute: 6-72 hours
Subacute: 3 days - 3 weeks
Chronic: > 3 weeks
This classification is based on clinical syndrome or combination of CT-Scan findings
Oxfordshire Classification
Disadvantage of utilization of oxfordshire
Poor in discriminating between lacunar and small volume infarction
Posterior circulation syndrome is defined as presence of
Isolated homonymous
Brainstem
Cerebellum
In 10 Asian countries using Oxford shire what is the most common syndrome
PACI 27%
LACI 25%
TACI 12%
POCI 10%
This classification is based on pathophysiology using advance diagnostics
TOAST classifcation
What is the other purpose of TOAST classification
Purpose of investigating the efficacy of anticoagulation
Large artery atherosclerosis is defined as
> 50% significant stenosis
Ulcerated plaque >2mm thick
1.5cm subcortical and subcortical infarct
Absence of cardioembolism