Chapter 1 Epithelium and Epithelial Glands Flashcards
Name 3 general functions of epithelium
Absorption
Secretion
Provide a barrier
Name 3 specialized functions of epithelium
Transport molecules across epi
Selective permeability
Sensory
Prevent transport of materials across epithelium
Selective permeability
A complete basement membrane has what two parts?
Basal lamina
Reticular lamina
In the basement membrane, this is made by epithelial cells
Basal lamina
In the basement membrane, this is made by fibroblasts in connective tissue
Reticular lamina
What is a partial basal membrane?
Basal lamina only
Epithelium is avascular, so how does it obtain nutrition?
By diffusion
List four types of cell junctions
Zonula Occludens
Zonula Adherens
Macula Adherens
Gap Junctions
This is a tight junction
Zonula Occludens
This is an adhesion belt
Zonula adherens
This is desmosomes
Macula adherens
What two components make up the macula adherens?
Tonofilaments
Protein plaque
This contains 6 proteins in a cylinder with a lumen
Gap junctions
Which cell junction functions in weak attachment?
Zonula adherns
For the junctional complex, list the order starting at the free surface
Zona occludens
Zona adherens
Macula adherens
List two types of epithelium
Simple and stratified
Epithelium that is a single cell thick
Simple epithelium
What are the three cell types in ciliated pseudo stratified epithelium?
Ciliated columnar
Goblet cells
Basal cells
These cells function as a stem cell
Basal cells
These cells function to move mucus
Ciliated columnar cells
These cells function to produce mucus
Goblet cells
List four surface specializations
Microvilli
Stereocilia
Cilia
Glycocalyx
These are known as brushborder or striated border
Microvilli
This is finger-like projections at the apical surface on some epithelial cells
Microvilli
These are extremely long microvilli not related to true cilia
Stereocilia
Thin apical hair-like extensions of the cytoskeleton
Cilia
Describe two features of cells with cilia
High # of mitochondria within cells for energy
Basal bodies block the surface so no absorption or secretion happens
Surface layer of glycoproteins and carbohydrates that covers some epithelium
Glycocalyx
Glycocalyx is produces by what?
Epithelial cells
When cell nuclei line up requiring energy
Polarization
Epithelium that is two or more cell layers thick
Stratified epithelium
What is the common function of stratified epithelium?
Protective function
This is the mitotic layer of skin
Stratum basale
This layer has spiny shaped keratinocytes
Stratum spinosum
This layer is present only in thick skin
Stratum lucidum
What layer are melanocytes found in?
Stratum basale
What layer are Langerhans cells found in?
Stratum spinosum
What layer are Merkel cells found in?
Stratum basale
This stratified epithelium is very rare
Stratified columnar
Patchy skin lesions that have an accelerated keratinocyte life cycle
Psoriasis vulgaris
Spots with extra pigment
Freckles
Patches which lack melanocytes
Vitiligo
Discoloration due to a proliferation of melanocytes
Moles (naevi)
Melanocytes become mitotically active and invade dermis
Malignant melanoma
Method of secretion by which the product is released into a duct or directly onto an epithelial surface
Exocrine secretion
Component dealing with primary function, for example, skeletal muscle fibers of the biceps
Parenchyma
Structural component, for example, blood vessels of the biceps
Stroma
What are the three methods of classifying exocrine secretion?
Morphology
Method of secretion
Products secreted
This method classifies the gland according to the shape of the secretory units and the ducts arrangement
Morphology
Secretory units
Tubular vs Acinar
Duct arrangement
Unbranched vs Branched
What are the three methods of secretion?
Merocrine
Holocrine
Apocrine
The most common method of secretion that releases vacuole contents only
Merocrine
Another name for merocrine
Eccrine
Secretes entire cell and intact vacuoles. Odor is present
Holocrine
Secretes intact vacuoles, cytoplasm, and membranes. Attracts bacteria and odor is present
Apocrine
Smallest division of a gland; a group of cells surrounding a cavity
Acinus
A small group of serous cells attached to a mucus acinus
Serous demilune
Cells with epithelial origin that are contractile
Myoepithelial cells
What do serous glands produce?
Proteins
This gland stains light and has flat, peripheral nuclei
Mucus glands
Signaling cell is close to target cell so the hormone does not enter the blood
Paracrine secretion
Signaling cell is its own target
Autocrine secretion