Chapter 1 Concepts plus regression review Flashcards
Three principles of design:
- replication
- randomization
- local control of error (blocking)
Categories of experimental problems
- Treatment comparisons
- Variable screening
- Response surface exploration
- System optimization
- System robustness
Steps to experiment planning
- State objective
- Choose response
- Choose factor and levels
- Choose experimental plan
- Perform experiment
- Analyze the data
- Draw conclusions and make recommendations
Experimental units vs observational units
- Experimental unit is item that is being experimented on and measured
- Observational unit can be thought of as a technical replicate
Replication does the following:
- Replicating experimental units:
- Allows estimation of the experimental error
- Improves the precision of the estimates
- Replicating observational units:
- mimizes the impact of measurement error
- does NOT estimate experiment error
Randomization does the following
- Distributes the impact of any systematic bias
- ensures fair comparisons
- if bias is present, inflatest the estimate of error
- Elimates presumption bias
Local control of error does the following
- Also called blocking
- reduces the random error among the experimental units
- controls for anything which might affect the response other than the factors
Two important forms of local control of error:
- blocking
- covariates
Block
Groups of homogeneous units
Blocking
- arranged so that within block variation is smaller than between block
- should be applied to remove the block-to-block variation
- randomization is applied to assignments of treatments within the blocks
Derive the LSE estimators without matrix notation
![](https://s3.amazonaws.com/brainscape-prod/system/cm/178/471/095/a_image_thumb.png?1454952981)
Derive the LSE estimators using matrix notation
(X’X)-1X’y
Derive the expectation, variance and covariance estimates of the LSE estimators without using matrix notation
![](https://s3.amazonaws.com/brainscape-prod/system/cm/178/471/224/a_image_thumb.png?1454953056)
Derive the expectation, variance, and covariance of the LSE estimators using matrix notation
![](https://s3.amazonaws.com/brainscape-prod/system/cm/178/471/319/a_image_thumb.png?1454954787)
How do you estimate σ2 in LSE
σ_hat2 =
MSE =
RSS/(N-k-1)=
SUM (yi - yi_hat)2 / (N-k-1)
yT(I-H)y / (N-k-1)
For SLR, N-k-1 = N-2
degrees of freedom in multiple linear regression
df overall = N-1
df model = k
df error = N-k-1
Note: this assumes k regressors + intercept
such that model matrix is n x k+1