Chapter 1: Biology and Behavior Flashcards
Organization of human nervous system
Central
- Brain and spinal cord
Peripheral
- Somatic
- Autonomic > Sympathetic and parasympathetic
Sensory neurons
Afferent neurons; transmit sensory info from receptors to spinal cord and brain
Motor neurons
Efferent neurons; transmit motor information from the brain and spinal cord to muscles and glands
Interneurons
Located between other neurons, most commonly found in brain and spinal cord; often linked to reflexive behavior (e.g. reflex arcs)
Reflex arc
In response to sensory info, interneurons send efferent motor signal to muscles before sensory info reaches brain
Somatic nervous system
Sensory and motor neurons distributed throughout skin, joints, and muscles
Autonomic nervous system
- Regulates heartbeat, respiration, digestion, temperature, and glandular secretions (involuntary/automatic muscles associated with many internal organs and glands)
- Subdivided into sympathetic and parasympathetic nervous systems
Parasympathetic nervous system
- “Rest and digest”
- Conserves energy, associated with resting and sleeping states; slows heart rate, stimulates digestion, constricts bronchi, contracts bladder
- Response mediated by acetylcholine
Sympathetic nervous system
- “Fight or flight”
- Activated by stress
- Increases heart rate, increases blood flow to required muscles, increases blood glucose concentration, relaxes bronchi, decreases digestion, dilates eyes, releases epinephrine into blood stream
Meninges (function and layers)
- Cover the brain with thick sheath of connective tissue
- Protect the brain, keep it anchored in skull, resorb cerebrospinal fluid
- 3 layers (inside to outside): pia mater, arachnoid mater, dura mater
Cerebrospinal fluid
- Aqueous solution in which the brain and spinal cord rest
- Produced by specialized cells that line the ventricles (internal cavities of the brain)
Hindbrain (components and functions)
- Medulla, pons, cerebellum, reticular formation
- Balance, motor coordination, breathing, digestion, general arousal process (sleeping, waking)
Cerebellum (location, function, and symptoms of damage)
- Hindbrain
- Balance and refined motor movements, speech, movement of eyes
- Damage: clumsiness, slurred speech, loss of balance (affected by alcohol)
Medulla (location and function)
- Hindbrain
- Vital functioning (breathing, heart rate, blood pressure, digestion)
Reticular formation (location and function)
- Neurons somas scattered throughout brainstem
- Arousal and alertness
Pons (location and function)
- Hindbrain
- Sensory and motor pathways between cortex and medulla
Midbrain
- Receives sensory and motor information from rest of body
- Involuntary reflexes in response to visual (superior colliculus) or auditory stimuli (inferior colliculus)
Forebrain
- Complex perceptual, cognitive, and behavioral processes
- Emotion and memory
- Components: cerebral cortex, basal ganglia, limbic system, thalamus, hypothalamus, posterior pituitary gland, pineal gland
Cortical maps
Cortex is stimulated with small electrode > individual neurons fire > behavioral or perceptual processes are activated; used by neurosurgeons
Electroencephalogram (EEG) (purpose and method)
- Measures electrical activity generated by larger groups of neurons
- Noninvasive; recorded by placing electrodes on scalp
- Used for research on sleep, seizures, brain lesions
Regional cerebral blood flow (rCBF) (purpose and method)
- Detects broad patterns of neural activity based on increased blood flow to different parts of brain
- Assumption: active regions have increased blood flow
- Noninvasive; patient inhales harmless radioactive gas, radioactivity is then correlated with blood flow
Computerized tomography (CT)
Multiple X-rays taken at different angles and processed by computer to produce cross-sectional slice images of tissue
Positron emission tomography (PET)
- Radioactive sugar is injected and absorbed into body, dispersion and uptake throughout target tissue is imaged
- Can’t give detailed structure, but can if combine with CAT and MRI
Magnetic resonance imaging (MRI)
- Uses magnetic field to interact with hydrogen and map out hydrogen dense regions of the body
- Dependent on reaction of hydrogen to magnetic field (same concept as NMR)
Functional magnetic resonance imaging (fMRI)
- Same technique as MRI, but measures changes associated with blood flow. Useful for monitoring neural activity
Radiofrequency lesions
- Used to destroy tissue on surface of brain and deep inside brain
- Wire inserted into brain to determine area, high frequency current heats up wire and destroys cells and axons
Neurochemical lesions
- Excitotoxic lesions: cause influx of calcium that excites the neuron to death
- Kainic acid: destroys cell bodies but not axons
- Oxidopamine: selectively destroys dopamine and norepinephrine neurons; models Parkinson’s disease
Cortical cooling (cryogenic blockade)
- Lesion method: cool neurons until they stop firing
- Cryoloop: surgically implanted between skull and brain; reversible unlike other techniques
Techniques for imaging brain structure, function, and both
Structure: CAT scan (CT), MRI
Function: EEG, MEG
Both: fMRI, PET (esp. when combined with CT/MRI)
Thalamus
- Forebrain
- Relay station for all sensory information except smell
- Receives sensory info and then transmits to appropriate area of cerebral cortex
Hypothalamus (general overview)
- Forebrain
- Controls 4 Fs: feeding, fighting, flighting, and mating
- Regulates autonomic nervous system to serve homeostatic functions: metabolism, temperature, water balance
- Integrates with endocrine system through hypophyseal portal system connecting it to anterior pituitary
- Further divided into lateral, ventromedial, and anterior hypothalamus
Lateral hypothalamus
- Hunger center; receptors detect when body needs food or water
- When this part is destroyed one [Lacks Hunger]
Ventromedial hypothalamus
- Satiety center; provides signals to stop eating
- Lesions to this area usually result in obesity
- [Very Much Hungry] when destroyed
Anterior hypothalamus
- Controls sexual behavior, regulates sleep and body temperature
- Damage inhibits sexual behavior