Chapter 1 Antibiotics and Resistance Flashcards
MRSA
Methicillin Resistant Staphylococcus Aureus
3 areas of science the MOL intersect
Bio, chem, medicine
What is science (2 answers)
- Collection of knowledge
2. A process –> systematic method of investigating
2 methods by which ethonol antiseptics kill bacteria
- dissolves the cell membrane which destroys the structure of the cell
- denatures the proteins inside the cell which kills the cell
Limitation to antiseptics
can only be used topiccally, not internally
can be used to prevent not to treat infection
differenaces btwn antiseptics and antibiotics
antiseptics- high concentration of active ingredient, can not be used inside the body, does not specfically target bacteria
antibiotic- low conc, inside bod (injection or pill), specfically targets bacteria
antibiotic
a drug that kills or INHIBITS/slows batericas GROWTH
flemming, howard florey, earnest chain
discovery of penniciln
how did Dorthy Hodgkin determine the molucular shape of penicilllin
x ray crystallography- bombarding crystals of penicillin w x rays
How does penicillin work
binds to the enzyme that catlyzes the reaction that makes the bacterias cell wall and prevents that enyme from doing that task
explain genetic mutation and why certain strains of bacteria are able to survive and reproduce in the preceance of antibiotics. what is the name of this process
evolution by natural selection
y is the development of new antibiotics not appealing to pharmaceutical companies
- ppl only use for a week (not so cost effective)
2. becomes obsolete real quick bc of resistance