chapter 1 Flashcards
1
Q
What is replication
A
making of a semi conservative replication of DNA
2
Q
What are the steps in replication
A
- Initiation- at origins and gets a helices
- Elongation- RNA primer goes 5-3
- Termination- @Ter site or when to forks meet
3
Q
Transcription steps
A
- initiation- RNA polymerase binds to the promotor
- Elongation- unwinds ssDNA
- Termination- stop codon
4
Q
Translation steps
A
- Initiation- MET onto tRNA to the P site– finds AUG
- Elongation- of polypep chain
- Termination- stop codon
- Ribosomal recycling- they dissociate
5
Q
Nucleotides
A
5-3
maintains a barrier and source of energy
stores genomic info and passes it down
NO — OH just H at 2’
6
Q
genome
A
DNA into circular or linear chromosomes and some have plasmids
7
Q
alkylating drugs
A
stop cell synthesis
8
Q
antimetabolites
A
substitute normal for something else and stops essential
9
Q
BRCA1
A
breast cancer- if u dont have this then more chance of mutations and cancer
10
Q
oncogenes
A
promotes tumors
11
Q
tumor supressor genes
A
stop divison in cell cycle
12
Q
DHFR
A
an antimetabolite and w/out this no nucleotides or amino acids will die
