Chapter 1 Flashcards
It was the principal obstacle to overcome.
Clotting
In 1942, blood was taken from three young men and given to______ in the hope of curing him.
Pope Innocent VII
Attempts to find nontoxic anticoagulant began in __?
1869
He recommended sodium phosphate.
Braxton Hicks
First example of blood preservation rsearch.
Sodium phosphate
In 1901, he discovered the ABO blood groups and he explained the serious rxns that occur in humans as a result of incompatible transfusions.
Karl Landsteiner
He carried out vein-to-vein transfusion of blood by using multiple syringes and a special cannula for puncturing the vein through the skin.
Edward E. Lindemann
He designed his syringe-valve apparatus that transfusions from donor to patient by an unassisted physician became practical,
Unger
In 1914, he reported the use of sodium citrate as as anticoagulant solution for transfusions.
Hustin
In 1915, he determined the minimum amount of citrate needed for anticoagulation and demonstrated its non-toxicity in small amounts.
Lewisohn
Early as 1916 when they introduced a citrate dextrose solution for the preservation of blood .
Rous and Turner
His pioneer work during World War II on developing techniques in blood transfusion and blood preservation led to establishment of a widespread system of blood banks.
Dr. Charles Drew
He was appointed director of the first American Red Cross blood bank at Presbvterian Hospital.
Dr. Charles Drew
In 1943, they introduced the formula for the preservative acid-citrate-dextrose (ACD).
Loutit and Mollison of England
He introduced an improved preservative solution called ______ (CPD) which was less acidic and eventually replaced ACD as the standard preservative used for blood storage.
Gibson, citrate-phosphate-dextrose
A volunteer donor can donate blood every ________
8 weeks
What are the Three steps or processes of donation process?
Educational reading materials
The donor health history questionnaire
Abbreviated physical examination
Plasma can be converted by ______ to a clotting factor concentrate that is rich in ______.
Cryoprecipitation
AHF antihemophilic factor
Whole blood can be separated into three components. What are they?
Packed RBCs, platelets, plasma
For a 110 pound donor, what is the maximum volume collected?
525 ml
These are used when collecting 500ml of blood, with the volume of anticoagulant preservative solution being increased from 63 ml to 70 ml.
Modified plastic collection system
How many days is a unit of whole blood prepared RBCs stored?
21-42 days
What is the total blood volume of most adults?
10 to 12 pints
Donor’s red cells are replaced within________ after donation.
1-2 months
