Chaps 46: Liver, Pancreas and Biliary Tract Problems Flashcards
A physician who has never been immunized for hepatitis B is exposed to the hepatitis B virus (HBV) through a needle stick from an infected patient. What should the infection control nurse inform both the physician and patient that treatment for the exposure should include?
a. Evaluation of liver function tests in 60 days
b. Active immunization with hepatitis B vaccine
c. Hepatitis B immunoglobulin (HBIG) injection
d. Both the hepatitis B vaccine and HBIG
ANS: D
The recommended treatment for exposure to hepatitis B in unvaccinated individuals is to receive both HBIG and the hepatitis B vaccine, which would provide temporary passive immunity and promote active immunity
A patient contracts hepatitis from food contaminated by a worker with hepatitis in a fast-food restaurant. During the icteric phase of the patient’s illness, what should the nurse expect serological testing to reveal?
a. HBsAg (hepatitis B surface antigen)
b. Anti-HBc IgM (antibody to HBV core antigen)
c. Anti-HAV IgG (antibody to hepatitis A virus, immunoglobulin G)
d. Anti-HAV IgM (antibody to hepatitis A virus, immunoglobulin M)
ANS: D
Hepatitis A virus (HAV) is transmitted through the oral–fecal route, and antibody to HAV IgM appears during the acute phase of hepatitis A.
While the nurse is obtaining a nursing history from a patient diagnosed with hepatitis C, what information reported by the patient indicates the highest risk factor for hepatitis C?
a. Sexual exposure
b. Injection drug use
c. Eating contaminated shellfish
d. Recent travel to an underdeveloped country
ANS: B
One of the highest risk factors for contracting hepatitis C is injection drug use.
During evaluation of a patient at an outpatient clinic, the nurse determines that administration of hepatitis B vaccine has been effective when a specimen of the patient’s blood reveals which of the following results?
a. HBsAg
b. Anti-HBs (antibody to hepatitis B surface antigen)
c. Anti-HBcAg (antibody to hepatitis B core antigen)
d. Anti-HBc IgM (antibody to hepatitis B core antigen, immunoglobulin M)
ANS: B
The presence of surface antibody to HBV (anti-HBs) is a marker of a positive response to the vaccine.
Serological testing of a patient reveals the presence of antibodies to the hepatitis C virus (anti-HCV). Which following nursing action is appropriate?
a. Schedule the patient for HCV genotype testing.
b. Teach the patient that the HCV infection will resolve in 2 to 4 months.
c. Administer immunoglobulin and the HCV vaccine.
d. Instruct the patient on self-administration of -interferon.
ANS: A
Genotyping of HCV has an important role in managing treatment and is done before drug therapy with -interferon or other medications is started.
A person who is homeless is hospitalized with severe anorexia and fatigue. She has mild jaundice and hepatomegaly, and her liver function tests are abnormal. The physician suspects viral hepatitis. In planning care for the patient, to which patient outcome should the nurse assign the highest priority?
a. Maintains adequate nutrition
b. Adapts to changes in appearance
c. Gradually increases tolerance for activity
d. Identifies source of exposure to hepatitis virus
ANS: A
The highest priority outcome is to maintain nutrition and collaborate with health care providers and family to provide an appropriate diet so that proper nutritional requirements can be provided.
A patient with acute hepatitis B asks the nurse if treatment is available for the condition. What should the nurse explain to the patient?
a. Patients with acute hepatitis B can be given HBIG to help reduce the symptoms.
b. A variety of antiviral medications are available to treat acute hepatitis B, but serious side effects limit their use.
c. No medication is available for treatment of HBV infection.
d. Chronic HBV infection can be treated with interferon and lamivudine (Heptovir) and adefovir (Hepsera).
ANS: C
No drug therapies are available to treat acute hepatitis, although -interferon and nucleoside analogues (i.e., lamivudine) may be used to treat chronic hepatitis B.
Combination therapy of -interferon and ribavirin (Rebetol) is being used to treat hepatitis C in a patient infected with human immunodeficiency virus (HIV). What will the nurse monitor for in the patient?
a. Blood glucose
b. Lymphocyte count
c. Potassium level
d. Serum creatinine
ANS: B
HCV treatment with a combination of interferon and ribavirin may reduce CD4+ counts, worsen leukopenia, and increase the patient’s risk for anemia. HIV medications may have to be altered because of the potential for drug interactions between some HIV medications and ribavirin.
During the acute phase of hepatitis, what would the nurse expect the patient’s laboratory results to include?
a. Increased stool urobilinogen
b. Decreased urinary urobilinogen
c. Decreased prothrombin time
d. Increased total serum bilirubin
ANS: D
During the acute phase of hepatitis, the nurse would expect the patient to have an increase in total serum bilirubin.
A 68-year-old patient has an abrupt onset of anorexia, nausea and vomiting, hepatomegaly, and abnormal liver function studies. Serological testing is negative for viral causes of hepatitis. During assessment of the patient, what is it most important for the nurse to ask the patient about?
a. Any prior exposure to people with jaundice
b. The use of all prescription and over-the-counter medications
c. Treatment of chronic diseases with corticosteroids
d. Exposure to children recently immunized for hepatitis B
ANS: B
The patient’s symptoms, the lack of antibodies for hepatitis, and the abrupt onset of symptoms suggest toxic hepatitis, which can be caused by commonly used over-the-counter drugs such as acetaminophen (Tylenol).
When teaching a patient recovering from hepatitis B about management of the illness, the nurse determines that additional teaching is needed when the patient makes which of the following statements?
a. “I should not drink alcohol for at least a year.”
b. “When I have recovered from this infection, I should have lifelong immunity to the virus.”
c. “When the jaundice is gone, I have recovered from my illness and the infection is cured.”
d. “I should use a condom during sexual intercourse until my tests for the virus are negative.”
ANS: C
After the acute (icteric) phase, there is a convalescent phase lasting several months
The nurse assesses a patient with cirrhosis and finds 4+ pitting edema of the feet and legs and massive ascites. The data indicate that the nurse should monitor which of the following?
a. Temperature
b. Albumin level
c. Hemoglobin
d. Activity level
ANS: B
The low oncotic pressure caused by hypoalbuminemia is a major pathophysiological factor in the development of ascites and edema.
A 32-year-old patient has early alcoholic cirrhosis diagnosed by a liver biopsy. In teaching the patient about the disease, it important for the nurse to inform her that the disease may be reversed at this point with which of the following interventions?
a. Vitamin B supplements
b. Abstinence from alcohol
c. Maintenance of a nutritious diet
d. Long-term, low-dose corticosteroids
ANS: B
The disease progression can be stopped or reversed by alcohol abstinence.
Which hepatitis virus has DNA as its characteristic virus type?
a. Hepatitis A
b. Hepatitis B
c. Hepatitis C
d. Hepatitis E
ANS: B
Hepatitis B virus has DNA as the virus type; all of the others have RNA as the virus type.
When assessing a patient for signs of impending coma resulting from hepatic encephalopathy, what should the nurse ask the patient to do?
a. Stand on one foot.
b. Extend both arms.
c. Ambulate with the eyes closed.
d. Perform the Valsalva manoeuvre.
ANS: B
Extending the arms allows the nurse to check for asterixis, a classic sign of hepatic encephalopathy.
When lactulose (Cephulac) 30 mL four times per day is ordered for a patient with advanced cirrhosis, he complains that it causes diarrhea. The nurse explains to the patient that it is still important for him to take the drug because the drug will create which of the following actions?
a. Promote fluid loss
b. Prevent constipation
c. Prevent gastrointestinal (GI) bleeding
d. Improve nervous system function
ANS: D
The purpose for lactulose in the patient with cirrhosis is to lower ammonia levels and prevent encephalopathy. Although the medication may promote fluid loss through the stool, prevent constipation, and prevent bearing down during bowel movements (which could lead to esophageal bleeding), the medication is not ordered for these purposes for this patient