Chap 6: Adrenergic Bronchodilators

Question 1

Identify a list of catecholamines

Answer 1

Dopamine
Epinephrine
Norepinephrine
Isoproterenol

Question 2

What are catecholamines inactivated by?

Answer 2

Catechol-O-Methyltransferase (COMT)

Question 3

Are all catecholamines bronchodilators?

Answer 3

No

Question 4

Which drugs are sympatholytics?

Answer 4

Phentolamine
Prazosin
Labetalol
Metoprolol
Propranolol
Timolol
Esmolol

Question 5

If your patient is diagnosed with persistent asthma, which type of drug would you recommend for maintenance/ rescue bronchodilation?

Answer 5

Rescue: Albuterol. short acting b agonist (SABA)

Maintenance: salmeterol, formoterol, arformoterol, indacaterol, olodaterol, and vilanterol. Long acting b agonist (LABA)

Question 6

What is the main indication for continuous nebulization for inhaled b agonists?

Answer 6

Useful in managing severe asthma to avoid respiratory failure, intubation, or mechanical ventilation

Question 7

Albuterol is available in which formulations?

Answer 7

Syrup: 2mg/5ml
SVN: 2.5mg
MDI: 2 puffs
oral tablets : 2,4,8 mg

Question 8

If a patient with glottic edema is in mild distress, what medication would be of benefit in this solution?

Answer 8

Racemic Epinephrine

Question 9

What is the main difference between salmeterol and formoterol?

Answer 9

Onset of formoterol is quicker than salmeterol

Question 10

You enter the room of a 2 year old patient who presents with the characteristics of “barking cough” found in croup. Once the diagnosis is confirmed, you may recommend which medication to help provide relief of subglottic swelling

Answer 10

Racemic epinephrine