Chap 27 Key Concepts Flashcards

1
Q

What are the 3 common peripheral nerve sheath tumors?

A
  1. Schwannomas
  2. Neurofibromas
  3. Malignant peripheral nerve sheath tumors
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2
Q

What do the 3 most common peripheral nerve sheath tumors arise from?

A

From cells of Schwann cell lineage

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3
Q

What are Schwannomas?

A

Encapsulated benign tumors that can be associated with NF2

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4
Q

What are neurofibromas?

A

Benign peripheral nerve sheath tumors that can sometimes be associated with NF1

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5
Q

What are the subtypes of neurofibromas?

A

Localized cutaneous, diffuse, or plexiform

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6
Q

What neoplasms can malignant peripheral nerve sheath tumors form?

A

De novo sporadic neoplasms or NF1-associated tumors from malignant transformation of a (plexiform) neurofibroma

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