Chap 27 Key Concepts Flashcards
1
Q
What are the 3 common peripheral nerve sheath tumors?
A
- Schwannomas
- Neurofibromas
- Malignant peripheral nerve sheath tumors
2
Q
What do the 3 most common peripheral nerve sheath tumors arise from?
A
From cells of Schwann cell lineage
3
Q
What are Schwannomas?
A
Encapsulated benign tumors that can be associated with NF2
4
Q
What are neurofibromas?
A
Benign peripheral nerve sheath tumors that can sometimes be associated with NF1
5
Q
What are the subtypes of neurofibromas?
A
Localized cutaneous, diffuse, or plexiform
6
Q
What neoplasms can malignant peripheral nerve sheath tumors form?
A
De novo sporadic neoplasms or NF1-associated tumors from malignant transformation of a (plexiform) neurofibroma