Chap 16

Question 1

a substance produced by a living source

Answer 1

Biologics

Question 2

any virus, therapeutic serum, toxin, antitoxin, or analogous
product employed for prevention, treatment, or cure of
diseases in humans.

Answer 2

Biologics

Question 3

refers to the use of a biologic product (a vaccine) to develop active immunity in the patient.

Answer 3

Vaccination

Question 4

innate, or native immunity depends on factors that are inborn

Answer 4

Natural immunity

Question 5

develops in response to antigen substances in the body

Answer 5

Naturally acquired active immunity

Question 6

develops in response to administration of a specific vaccine or toxoid

Answer 6

Artificially acquired active immunity

Question 7

composed of killed whole bacteria or viruses Vaccines grown in cultures.

Answer 7

Inactivated vaccine

Question 8

live but significantly weakened
microorganisms

Answer 8

Attenuated vaccines

Question 9

occurs by introduction of the immunoglobulins produced in
anothe individual (human or animal) into the host

Answer 9

Passive immunity

Question 10

occurs by placental transmission
of immunoglobulin gamma (IgG) from the mother to the fetus.

Answer 10

Naturally acquired passive immunity

Question 11

Produced by infected host or produces in-vitro are given to healthy host

Answer 11

Artificially acquired passive immunity

Question 12

Storage of biologics

Answer 12

2-8C or 35-46C

Question 13

implies continuity from the manufacturer’s refrigerator to one’s pharmacy, clinic, or office to administration

Answer 13

Cold chain

Question 14

Open the door how many times only?

Answer 14

no more than four times per day

Question 15

Vaccines should be stored in?

Answer 15

Top or bottom shelves

Question 16

a suspension of attenuated (live) or inactivated (killed) microorganisms or fractions thereof that are administered to induce immunity and prevent disease.

Answer 16

Vaccine

Question 17

organism is grown in a suitable broth medium organisms are treated with phenol or formaldehyde

Answer 17

Bacterial vaccines

Question 18

employ purified antigen subunits produced with use of recombinant DNA

Answer 18

Bacterial vaccines

Question 19

cannot be grown on inanimate media

Answer 19

Viral vaccine

Question 20

can be developed in embryonic egg, cell cultures of chick embryos, human diploid cell culture, monkey cell culture, skin of living calves, and intact mice.

Answer 20

Viral vaccine

Question 21

developed from antigenic material procured from the tumor of the patient

Answer 21

Autologous tumor vaccines

Question 22

These cells are killed or attenuated and reinfused into the patient.

Answer 22

Autologous tumor vaccines

Question 23

use the concept of shared or tumor-specific. These vaccines are produced from cell lines that express tumor-specific or shared TAAs.

Answer 23

Allogeneic tumor vaccines

Question 24

The beneficial aspect of this
vaccine is that it can be used in a wide population of patients.

Answer 24

Allogeneic tumor vaccines

Question 25

are three-dimen-sional immunogenic regions on the antibody that binds antigen.

Answer 25

Anti-idiotypic vaccines

Question 26

- are combined with an adjuvant and given as a vaccine. - Because the anti-idiotypic antibody closely resembles the antigen, these can be usedto induce immune responses (cellular,antibody-antigen) to a given antigen.

Answer 26

Anti-idiotypic vaccines

Question 27

allows a DNA template to be placed within a cell, transcribed into messenger RNA, and expressed as a costimula-tory protein

Answer 27

Gene therapy

Question 28

source of homologous sera is the pooled plasma of adult donors

Answer 28

Human Immune Sera

Question 29

produced by inoculating horses with increasing doses of the toxoids and exotoxins.

Answer 29

Antitoxins

Question 30

produced by inoculating horses with the venom of selected species and harvesting the plasma.

Answer 30

Antivenins

Question 31

the first intranasal live attenuated influenza virus (LAIV) vaccine

Answer 31

FluMist

Question 32

should not be used by px under aspirin therapy or has history of Guillain-Barre syndrome, pregnant

Answer 32

Influenza

Question 33

is indicated to treat axillary hyperhidrosis, cervical dystonia (CD)

Answer 33

Botulinum Toxin Type A

Question 34

for the temporary improvement in the appearance

Answer 34

Botox cosmetic

Question 35

Stored in a refrigerator ______for up to ________.

Answer 35

2-8C, 24 months

Question 36

Recommended diluent in toxins

Answer 36

0.9% w/v NaCI injection

Question 37

is a preservative-free injectable solution, that is, 5000 U/mL.

Answer 37

Botulinum Toxin Type B - Botulinum Toxin Type B

Question 38

are injected ID and the site inspected for development of a hypersensitivity reaction.

Answer 38

Antigens

Question 39

determined by the extent of induration (in millimeters) and degree of reaction, from slight induration to vesiculation and necrosis.

Answer 39

Positive reaction