Changes In Gland During Preg

Question 1

Sheehan syndrome

Answer 1

Sudden hypotension following PPH May cause infarction of pituitary gland which is very sensitive to blood during pregnancy

Question 2

Pituitary gland hormones elevated during pregnancy

Answer 2

Gh
Prl 
ACTH(does not cross placenta)
Crh 
Oxytocin

Question 3

Wt gain during pregnancy due to pregnancy

Answer 3

Gh variant made by syncitiotrophoblast

Question 4

Iodine intake during pregnancy should be inc from

Answer 4

100 to 200 ug/day

Question 5

Transient gestational thyrotoxicosis due to

Answer 5

Thyrotropic effect of hcg causes hyperthyroidism in pregnancy

Question 6

Fetal thyroid functions starts at

Answer 6

12 weeks (T12)

Question 7

Thyroid hormones which crosses placenta

Answer 7

TRH
TSH (minimally)
Iodine
Drugs used to treat hyperthyroidism

Question 8

Physiologic hypercortisolism due to

Answer 8

1) inc plasma cortisol t1/2
2) delayed plasma clearance by kidneys
3) resetting of hypothalamic pituitary adrenal feedback mechanism

Question 9

Pth status in pregnancy

Answer 9

It doesn’t cross the placenta and is normal but calcium ions do cross the placenta against the conc gradient by inc in maternal 1,25 dihydoxyvitamin D levels

Question 10

Endocrine control of lactation stages

Answer 10

1) mammogenesis preparation of breast)
2) lactogenesis (syn and secretion of milk)
3) galactokinesis (ejection of milk)
4) galactopoeisis (maintenance of lactation)