Chagas Flashcards
1
Q
Incidence in latin america
A
25% of population exposed.
2
Q
Life Cycle of T Cruzi
A
- Infected Triatomine bug bites human (Triatoma, rhodinius)
- T Cruzi epimastigotes have been dividing within the bug to create infective metacyclics.
- These are excreted in faeces after a blood meal. Highly itchy, making is scratch them into our skin.
- Circulating circulating trypomastigotes make their way to muscles where they become pseudocysts containing dividing amastigotes.
- Trypomastigotes continue to circulate creating potential for ongoing infection in other bugs.
INDIRECT HOST.
3
Q
Label and name
A
4
Q
What is this?
(hint: it’s in muscle)
A
5
Q
What are the major clinical manifestations of Chaga’s disease?
A
6
Q
Diagnosis?
A
ELISA (gold standard)
PCR
Xenodiagnosis (cut open bugs after tehy feed on people to look for parasites)
Statpack RDT
7
Q
How many strains of T Cruzi are there?
A
6: v & VI are HYBRIDS
8
Q
What methods of transmission control are there?
A
Noireau traps (vector)
Transfusion control (BB)
9
Q
A
