Ch.7 Pt. 2 Flashcards

(41 cards)

1
Q

What 3 separate and Interacting systems are the Somatosensory System made up of?

A
  1. Exteroceptive: External Stimuli
  2. Proprioceptive: Body Position
  3. Interoceptive: Body conditionds (temp, blood pressure)
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2
Q

What are the 3 parts of the Exteropcetive System?

A
  1. Mechanical Stimuli (touch)
    - Mediated by 4 key receptors
  2. Thermaal Stimuli (temp)
  3. Noicipetion (pain)
    - 2 and 3 are not really distinct in the cellular sense
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3
Q

What are the 3 layers the skin is comprised of?

A
  1. Epidermis -> outermost layer (thinnest)
  2. Dermis -> middle layer (rich in nerve fibers, blood vesicles
  3. Hypodermis - innermost layer - provides an anchor for muscles
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4
Q

Mechanoreceptors of the skin: What are the 5 Receptors for touch (5)

A
  1. Merkels Disk (dermis) pressure
  2. Meissners Corpuscle (dermis) light touch
  3. Hair follicle receptor (dermis)
  4. Pacinian Corpuscle (hypodermis) vibration
  5. Ruffinis Ending (hypodermic) stretch
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5
Q

Adaptation:

A

You do not feel your clothes against you skin unless you bring it to your attention (due to adaptation)

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6
Q

(Adaptation in the somatosensory system) What are the two types of receptors?

A
  1. Tonic Receptors- Show little adaptation, in response to continuous stimuli they show little to no change in AP rate
  2. Phasic Receptors: show adaptation - in response to continuous stimulation they rapidly decrease AP firing rate
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7
Q

Why do we have adaptation?

A

Tuned to detect amplify CHANGE in the environment

- Change is more likely to signify meaningful events

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8
Q

Suppression:

A

Pretty much telling receptors to quiet down

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9
Q

What are the 2 Mechanisms of Suppression?

A
  1. Accessory Structures - closing the eyelids deuces light information reaching the eyes
  2. Top down Processing - CNS modulation of sensory information. The cortex and thalamus can suppress some sources of information and amplify others
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10
Q

How Mechanoreceptors Work: (Pacinian Corpuscles as example)

A
  • Stimuli to the corpuscle (like vibration) produce a graded potential proportional to the intensity of the stimulus
  • If the graded potential is sufficient and AP fires
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11
Q

More in depth on How Mechanoreceptors work with pacinian corpuscles as example

A
  1. Mechanostimulation deforms the corpuscle
  2. Deformation stretches the tip of the axon
  3. Stretching opens mechanically gated ion channels
  4. Stretch sufficient enough cations enter and AP fires
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12
Q

If the corpuscle is removed this cells does not show an adaptation response - continuous vibration elicits a continuous response

A

.

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13
Q

Meissners Corpuscle (touch)

A
  • Fewer than Merkels Discs and have less spatial resolution
  • Respond to changes in stimuli between skin and surface
  • Provide info about texture
  • Adapt quickly to continued stimuli
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14
Q

Merkels Discs (touch)

A
  • Receptive fields have an inhibitory surround (increases spatial resolution)
  • Receptive to edges and isolated points on a surface (braille)
  • Adapt slowly to continuous stimulations
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15
Q

Ruffini’s Ending (stretch)

A
  • Very few of them - they have large receptive fields
  • Detect streching in the skin when we move our fingers or limbs
  • Adapt slowly to continued stimuli
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16
Q

Pacinian Corpuscle (vibration)

A
  • Detect Vibration - when skin moves across texture on a surface
  • They respond quickly (fast acting) to appropriate stimuli
  • They adapt quickly in response to continued stimuli
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17
Q

What are Dermatomes?

A

” Bands” of skin that send their sensory information to different dorsal roots of the spinal cord. Each dermatome is the section of skin that is innervated by a given dorsal root

18
Q

What are the 4 Types of Dermatomes? (from the brain downward)

A
  1. Cervical
  2. Thoracic
  3. Lumbar
  4. Sacral
19
Q

Ascending Sensory Circuit (Dorsal-Column-Medial-Lemniscus system)

A
  • Tends to carry info about touch and perception
  • First synapse in the dorsal column nuclei of the medulla
  • Information does not intersect until within the brain at the dorsal column nuclei
  • Goes from the spinal cord to the hindbrain to the forebrain
20
Q

Cortical Areas of Somatosensation:

A

Primary Somatossensory Cortex (SI): more sensitive more cortex, input largely contralteral
SII: maily input from SI: soma topic; input from both sides of the body
- Much of the output from SI and SII goes to the association cortex in the posterior parietal lobe

21
Q

Somatotopic Map In the Cortex:

A

Organized like the primary somatosensory cortex, according to a map of the surface of the body
- Often called the sensory homunculus

22
Q

Effects of Damage to the Primary Somatosensory Cortex

A

Effects of damage to the primary somatosensory cortex are often mild
- Likely due to numerous parallel pathways

23
Q

Somatosensory Agnosias

A
  • Asterognesia: inability to recognize objects by touch, pure cases are rare: other sensory deficits are usually present
  • Asomatognosia: the failure to recognize parts of ones own body (eg: the case of the man who fell out of bed)
24
Q

The highest level of the sensory hierarchy is made up of areas of association cortex in the ________ and _______ _____ _____

A

prefrontal and posterior parietal cortex

25
What does The posterior parietal cortex contains
bimodal neurons which are neurons that respond to activation of two different sensory systems
26
What does pain provide?
Pain provides powerful feedback to avoid injury
27
What does short term pain promote?
Withdraw response
28
What does long lasting pain promote?
Recuperative behaviours (resorting health behaviours)
29
Expresion of pain is a social signal of ______
danger
30
When it comes to Pain Signalling what receptors get the first message regarding pain?
Peripheral Receptors
31
Pain usually results from what?
destruction or injury to certain fibres
32
Damaged tissues releases chemical mediators of pain such as:
neuropeptides, serotonin, histamine and prostaglandins
33
Receptors that respond to noxious (harmful) stimuli are called what?
Nociceptors - usually free nerve endings
34
What do Free Nerve Endings do?
Release specialized receptor proteins on their cell membrane that respond to various signal (eg. changes in temperature)
35
What is Capsaicin?
Chemical that makes chill peppers hot - Some nerve endings have a receptor that binds capsacin - called TRPVI (this would be the second stage of a burnt hand - the dull long lasting pain) - Chili peppers taste hot because capsaicin activates TRPVI receptors in the body that detect noxious heat
36
TRP 2 Receptors
Found on free nerve endings, detect higher heat than TRPVI receptors -This would be the first stage a burnt hand, the initial super hot pain
37
Anterolateral System (Ascending Sensory Circuit)
- Mainly pain and temperature - Synapse upon entering the spinal cord and immediately decussate - 3 tracks - Ascend in the anterolateral portion of the spinal cord
38
Descending Pain Circuit, why are some injuries that should be accompanied by extreme pain not painful?
The brain can send inhibitory signals down the spinal cord to prevent the subjective experience of pain
39
What is Neuropathic Pain?
Severe chronic pain in the absence of a recognizable pain stimulus
40
What is neuropathic pain likely a result of?
Pathology of the nervous system linked to an injury | - Very resistant to treatment
41
Rubber hand treatment can be used to treat what?
phantom limb pain, a type of neuropathic pain