Ch5 Membrane Structure & Function Flashcards
Plasma membrane
Separate cell from surrounding, contains an abundance of phospholipid
Cellular membranes
Fluid mosaics of lipids and proteins
Selective permeability
Allow some substances to cross it more easily than others
Amphipathic molecules
Phospholipids, containing hydrophobic and hydrophilic regions
Fluid Mosaic model
States that a membrane is a fluid structure with a “mosaic” of various proteins embedded in it
Phospholipid structure consists of?
Glycerol, a 3-carbon poly alcohol & 2 fatty acid is attached to the glycerol (Nonpolar and hydrophobic a.k.a. water fearing)
spontaneously forms a bilayer, fatty acids are on the inside but phosphate groups are on both servers surfaces
Phospholipids arrange and a?
Bilayer
Bilayers are…?
Fluid
What two things can move through the membrane?
Individual phospholipids and proteins
Membrane switch from a fluid state a solid state…?
When temperature cools
Cholesterol
Steroid that has different effects on membrane fluidity at different temperatures a.k.a. “fluidity buffer “
- In warm temperatures such as 37°C cholesterol restrains movement of phospholipids
- cool temperatures it maintains fluidity by preventing tight packing
Membrane
A collage of different proteins, often group together, embedded in the fluid matrix of the lipid bilayer that determines most of the membrane’s specific function
Peripheral proteins
Bound to the surface of the membrane
Integral proteins
Penetrates the hydrophobic core
Transmembrane proteins
Hydrophobic regions of an integral protein consists of one or more stretches of nonpolar amino acids
Six major functions of membrane proteins
- Transporter
- Enzyme
- Cell surface receptor
- Cell surface identity marker
- Cell to cell adhesion
- Attachment to the cytoskeleton
Glycolipids
Forms when membrane carbohydrates covalently bond to lipids
Glycoproteins
(More common) forms when membrane carbohydrates covalently bond to protein
A process control by the plasma membrane…?
When a cell must exchange interior materials with its surroundings, selectively permeable regulates the cell molecular traffic
Transport proteins
Allow passage of hydrophilic substances across the membrane
Channel proteins
A type of transport proteins that has a hydrophilic channel that certain molecules or ions can use as a tunnel
Aqua Porins
Channel proteins that facilitate the passage of water
Carrier proteins
Type of transport protein that bind to molecules and change shape to shuttle them across the membrane
Passive transport
Diffusion of a substance across a biological membrane in which no energy is required and the molecules move in response to a concentration gradient… Spontaneous process