Ch.3 Uppers Cocain Flashcards
Cocain Hydrochloride
- Extract from Coca plant
-Max absorption .75mg
When was it isolated?
1816
Where was it included and then was extracted in 1886?
it was an original formula of Coca Cola and had some extracts of the coca leaf
What does uppers do to your heart ?
- Raise heart rate
- Constricts blood vessels
- 20-30 unit increase in blood pressure
- heart attack
Anhedonia
inability to archive pleasure
Do uppers have an effect on parkinsosons ?
There’s a higher risk of Parkinson’s disease
- it damages DA transporters in Basal ganglia
which neurotransmitter forces to release
NE/E and E
What neurotransmitter is blocked from re-uptake
Blooks DA
- NE/E, DA, 5HT
Which part of the brain becomes overstimulated with too much DA
Amygdala
What happens when cocaine effects the basal ganglia
it inhibits movement pathways
How many half lifes
1/2 life in 1 hour
How long is the duration of being high
20-30 mins
Which substance increase dopamine ?
all addicted substance increase dopamine