Ch.3 Uppers Cocain Flashcards

1
Q

Cocain Hydrochloride

A
  • Extract from Coca plant
    -Max absorption .75mg
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2
Q

When was it isolated?

A

1816

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3
Q

Where was it included and then was extracted in 1886?

A

it was an original formula of Coca Cola and had some extracts of the coca leaf

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4
Q

What does uppers do to your heart ?

A
  • Raise heart rate
  • Constricts blood vessels
    • 20-30 unit increase in blood pressure
  • heart attack
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5
Q

Anhedonia

A

inability to archive pleasure

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6
Q

Do uppers have an effect on parkinsosons ?

A

There’s a higher risk of Parkinson’s disease
- it damages DA transporters in Basal ganglia

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7
Q

which neurotransmitter forces to release

A

NE/E and E

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8
Q

What neurotransmitter is blocked from re-uptake

A

Blooks DA

  • NE/E, DA, 5HT
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9
Q

Which part of the brain becomes overstimulated with too much DA

A

Amygdala

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10
Q

What happens when cocaine effects the basal ganglia

A

it inhibits movement pathways

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11
Q

How many half lifes

A

1/2 life in 1 hour

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12
Q

How long is the duration of being high

A

20-30 mins

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13
Q

Which substance increase dopamine ?

A

all addicted substance increase dopamine

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