Ch.2 Cell Metabolism + Death Flashcards
Messy cell death
Necrosis
What happens with necrosis
- Cell swells
- Organelles fall apart
- Harm neighbor cells
- Inflammatory response
Tidy cell death
Apoptosis
What happens with Apoptosis
- Cells shrink
- Cells break into tiny blebs
- Neighbors are unharmed
- Remains eaten by immune cells
Anabolism
Breaks ATP. Is a endergonic rxn that uses energy anytime something is synthesized
What does anabolism involve
- Biosynthesis
- Dehydration (-H2O)
Catabolism
Makes ATP exogenic rxn that releases anergy when glucose is used to make ATP
What does catabolism involve
- Degrative
- Hydrolytic (+H2O)
How is mitochondria involved with cell metabolism
- Major site of ATP production
- Contains enzymes for: Citric acid cycle + electron transport chain
Metabolism
Sum of all chemical rxns
What is ATP
Adenosine triphosphate, adenosine + sugar
What are the steps to make ATP in a cell
- Glycolysis
- Citric Acid Cycle
- Electron Transport Chain
Glycolysis
Chemical process that breaks glucose into pyruvic acid molecules
Steps in glycolysis
Glucose goes in, follows the 10 steps (Generates 2 ATP- glucose pieces picked up by vit b)
What does glycolysis produce
2 pyruvic acid, 2 ATP, 2 NADH
Citric Acid Cycle
Requires O2, takes 2 pyruvic acid from glycolysis into 8 biochemical rxns
What does the citric acid cycle produce
8 NADH, 2 FADH, 2 ATP
Electron Transport Train
Requires O2, series of rxns in the inner mitochondrial membrane. Largest source of ATP
What does the electron transport chain produce
34 ATP
How much ATP is produced by the sequences
38 ATP -2 for transport = 36 ATP
Plasma Membrane
Thin layer of lipids and proteins that are the outer boundary of the cell (Phospholipid Bilayer)
What does the plasma membrane do
- Controls movement in and out of cell
- Participates in the joining of cells
- Has a role in the response to environmental changes
What is the Phospholipid Bilayer made of
Made of two alcohol and phosphate heads and a fatty acid tail, follows a fluid mosaic model
What is the role of carbohydrates in the plasma membrane
- Cell identification markers
- guides cells to designated areas
- Allow for growth and create boundary’s
What is the role of cholesterol in the plasma membrane
- Stabilize membrane over a range of temps
- Prevent fatty acids from crystalizing
- Contribute to cell fluidity
Functions of the membrane proteins
- Span across membrane to form channels across the lipid bilayer
- Carrier molecules
- Docking marker acceptors
- Membrane bound enzymes
- Receptor sites
- Cell Adhesion Molecules (CAMs)
- Important for cells to recognize “self” in cell to cell reactions
Functions of the lipid bilayer
- Forms the basic structure of the membrane
- Forms a barrier to water-soluble substances
Function of membrane carbohydrates
- Self-identity markers
- Contain surface markers used during tissue growth