Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

hema sem 1 > ch1 HEMATOPOIESIS > Flashcards

ch1 HEMATOPOIESIS Flashcards

1
Q

Homogenous, continuous, aqueous solution in the cytoplasmic matrix

A

Cytosol

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Macromolecular complexes composed of small and large subunit of rRNA and many accessory ribosomal proteins. Ribosomes are found free in the cytoplasm or on the surface of rough endoplasmic reticulum Ribosomes serves as the site of protein synthesis

A

Ribosomes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q
  • Synthesizes phospholipids and steroids
  • Detoxifies drugs
  • Stores calcium
A

Smooth endoplasmic reticulum

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Synthesizes most membrane-bound proteins

A

Rough endoplasmic reticulum

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Term used for the non-mitosis stages of the cell cycle, that is, G1, S, and G2.

A

Interphase

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Two identical daughter cells are produced, each of which receives one entire set of the DNA that was replicated during the S phase

A

Mitosis – M phase

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Duration of Mitosis

A

1 hour

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q
  • Also known as: Gap 1 phase
  • Cell grows rapidly and performs its cellular functions
  • Period of cell growth and synthesis of components necessary for replication.
A

Interphase – G1 phase

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q
  • Also known as: Synthesis phase
  • DNA is replicated
  • An exact copy of each chromosome is produced and they pair together as sister chromatids.
  • The centrosome is also duplicated during the S stage.
A

Interphase – S phase

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q
  • Also known as: Gap 2 phase
    Period when the cell produces materials essential for cell division
  • Tetraploid DNA is checked for proper replication and damage
A

Interphase – G2 phase

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Duration of G1 Phase

A

11 hours

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Duration of S Phase

A

8 hours

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Duration of G2 Phase

A

4 hours

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

G0 Phase is also known as

A

Resting Phase

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q
  • Cells are not active in cell cycle
  • Some cells may enter this phase after G1 phase
  • Normally do not re-enter the cell cycle and remain alive performing their function until apoptosis occurs
A

G0 Phase

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q
  • Occur at the end of G1 phase
  • Before DNA replication in S phase
  • At the end of G2 phase before M phase
A

Checkpoint

17
Q

Present in small numbers in the bone marrow (<1% cells in the bone marrow)

A

Stem Cells

18
Q
  • These cells are present in the first few hours after an ovum is fertilized.
  • Can develop into any human cell type, including development from embryo into fetus.
  • The most versatile type of stem cell.
  • Give rise to all cell lineage
  • Gives rise to CFU-S and CFU-L
  • Can develop into any human cell type, including development from embryo into fetus.
A

Totipotent hematopoietic stem cell (THSC)

19
Q
  • These cells are capable of giving rise to multiple lineages of blood cells
  • Example: CFU-S and CFU-L
A

Pluripotential or Multipotential stem cell

20
Q

The identification and origin of stem cells can be determined by immunophenotypic analysis using

A

Flow Cytometry

21
Q

Characteristic of stem cell

A
  • Capable of self-renewal
  • Give rise to differentiated progeny
  • Able to reconstitute the hematopoietic system of a lethally irradiated host
22
Q

Fate of Hematopoietic Stem Cell (HSC)

A
  • Self-renewal
  • Differentiation
  • Apoptosis
23
Q
  • Glycoprotein
  • Encoded on Chromosome 1q
  • Stem cell marker
A

Stem Cells

24
Q

Is a continuous, regulated process of blood cell production that includes cell renewal, proliferation, differentiation, and maturation.

A

Hematopoiesis

25
Q

Is a collective term used to describe the process involved in the production of blood cells from human stem cells (HSCs) with subsequent cellular differentiation and development

A

Hematopoiesis

26
Q

These processes result in the formation, development, and specialization of all of the functional blood cells that are released from the bone marrow to the circulation.

A

Hematopoiesis

27
Q

In healthy adults, hematopoiesis is restricted primarily to the

A

Bone Marrow

28
Q

Hematopoiesis occurs in the following parts of the body:

A

Bone marrow, liver, spleen, lymph nodes, and thymus

29
Q

In fetus, hematopoiesis takes place at various intervals in the

A

Liver, spleen, thymus, bone marrow, and lymph nodes

30
Q

Major locations of Hematopoiesis

A

Yolk sac, aorta-gonad-mesonephros (AGM) region, fetal liver, bone marrow, and thymus.

31
Q
A

hema sem 1 (1 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions