Ch. 9 Central Nervous System Flashcards
Men have 6x more ___ matter than women.
Gray matter
Women have 10x more ___ matter than men.
White matter
What is secreted by the choroid plexus?
Cerebrospinal fluid
CSF vs. Plasma
Concentration of K+ in CSF?
Concentration of H+ in CSF?
Lower K+
Higher H+ than plasma
About how many times a day does the CSF change? (Replenish itself?)
3 times
What is the function of the choroid plexus?
transport ions and nutrients from the blood in CSF
CSF is secreted into the ____ and flows through the _______ space & cushions the CNS
ventricles, subarachnoid space
Why are brain capillaries so much less permeable than other capillaries?
The endothelial cells form tight junctions with one another that prevent solute movement between the cells.
When dopamine is administered to a patient that has Parkinson’s disease, why is it ineffective?
It is unable to cross the blood-brain barrier
Which dopamine precursor is allowed to treat the Parkinson’s disease deficiency?
L-dopa
How can L-dopa treat Parkinson’s disease rather than dopamine?
It is transported across the cells of blood-brain barrier on AA transporter. Once it reaches interstitial fluid, dopamine is metabolized.
What do astrocytes secrete? What do they promote?
Secrete paracrine glands.
Promote tight junction formation
Where is the “vomiting” center located?
Medulla oblongata
How much % of the blood pumped by the heart goes to the brain?
15 %
Progressive hypoglycemia ( low blood glucose levels) leads to
confusion, unconsciousness & eventually death