Ch. 7 Neoplasia

Question 1

derived from tooth forming tissues, composed of epithelium, mesenchyme, or both, most are benign, but rare malignant forms exist.

Answer 1

Odontogenic tumors

Question 2

aggressive, slow growing, but benign, occurs in maxilla or mandible, but mostly by ramus or molar area in mandible, unencapsulated, infiltrates into the surrounding area. Multilocular, honeycomb, soap bubble appearance, blast, rises up along the border of ramus vs. OKC.

Answer 2

Ameloblastoma

Question 3

hard painless mass, benign, rare, derived from dental lamina, aka Pindborg tumor, unilocular, or multilocular, More often in mandible in bicuspid and molar area. Noticeable peaking in incidence in 40s, amyloid like material is seen with calcifications within deposits.

Answer 3

Calcifying Epithelial Odontogenic tumor

Question 4

encapsulated, benign, 70% occur in females under age of 20, 70% involve anterior portion of jaws, more common in maxilla, may be associated with impacted teeth, surrounded by connective tissue capsule.

Answer 4

Adenomatoid Odontogenic tumor

Question 5

non aggressive, lined by odontogenic epithelium, mostly in individuals under age of 40, well defined, uni or multilocular, may have calcifications. Has characteristic ghost cell keratinization.

Answer 5

Calcifying Odontogenic Cyst

Question 6

Epithelial Odontogenic tumors

Answer 6

1. Ameloblastoma
2. Calcifying Epithelial Odontogenic tumor
3. Adenomatoid Odontogenic Tumor
4. Calcifying Odontogenic Cyst

Question 7

Mesenchymal Odontogenic tumors

Answer 7

1. Odontogenic Myxomas
2. Central Cementifying and Ossifying fibromas
3. Benign Cementoblastoma

Question 8

benign, nonencapsulated, infiltrating, between 10-29 years of age, multilocular with poorly defined margins, may be large and displace teeth, mostly in mandible, **Sunburst pattern! Surgical excision may recur.

Answer 8

Odontogenic Myxoma

Question 9

benign, well circumscribed, occurs in third and fourth decades, mostly females, 90% occur in mandible, causes facial asymmetry, varies from radiolucent to radiopaque depending on amount of calcifications, composed of fibrous connective tissue and calcifications. Can become peripheral ossifying fibroma- on gingiva or alveolar bone, or central ossifying fibroma-causes facial asymmetry.

Answer 9

Central cementifying and ossifying fibromas

Question 10

radiopaque well defined mass with surrounding radiolucent halo including roots, teeth are vital, painful, localized mainly in molar area of mandible, enucleation of tumor and removal of involved tooth, does not recur.

Answer 10

Benign Cementoblastoma

Question 11

Mixed tumors

Answer 11

1. Ameloblastic fibroma
2. Compound odontoma
3. Complex odontoma
4. Ameloblastic fibro-odontoma

Question 12

rare, benign, nonencapsulated, young children and young adults, mostly males,

Answer 12

Ameloblastic fibroma

Question 13

mass resembles a tooth, located in anterior maxilla

Answer 13

Compound odontoma

Question 14

mass does not resemble a tooth, located in posterior mandible. Both can occur over an unerupted tooth.

Answer 14

Complex odontoma

Question 15

Composed of ameloblastoma-like epithelium, mesenchyme, and odontoma, occurs during tooth development exclusively, under 20 years of age in posterior mandible.

Answer 15

Ameloblastic fibroma

Question 16

reactive lesion, arises from chronic irritation, begins as pink papule to nodules, one of most common oral lesions, buccal mucosa, labial mucosa,

Answer 16

Irritation fibroma

Question 17

can displace a tooth, most likely developed from inflammatory hyperplasia of periodontal ligament cells, usually anterior maxilla in females in their 20s.

Answer 17

Peripheral ossifying fibroma

Question 18

dome shaped swelling, mostly in interdental papilla, anterior to molars, originates from PDL, most common in females, often occurs in young individuals.

Answer 18

Peripheral odontogenic tumors

Question 19

most common soft tissue tumor, blunt force trauma precedes its development usually, excision, unlikely to recur, malignant form is liposarcoma, rare in oral cavity, excise, tendency to recur, each recurrence, prognosis becomes less favorable outcome. Most commonly occurs on buccal mucosa or vestibule.

Answer 19

Lipoma

Question 20

large cells with granular cytoplasm, occurs in mesenchymal cells, on tongue

Answer 20

Granular cell tumor

Question 21

composed of cells resembling those in granular cell tumors but occurs on anterior maxillary gingiva, can be sessile or pedunculated

Answer 21

Congenital Epulis

Question 22

soft, aka gingival cyst or epstein pearls,

Answer 22

Dental lamina cyst

Question 23

Most common head and neck malignant soft tissue tumor in children

Answer 23

Rhabdomyosarcoma

Question 24

Neoplasm occurs most commonly in buccal mucosa or vestibule

Answer 24

Lipoma

Question 25

Tumor associated with von recklinghausen disease

Answer 25

Neurofibroma

Question 26

infrequent, arises from smooth muscle, male adults, on hard and soft palate, buccal mucosa, lip, and tongue.

Answer 26

Leiomyoma

Question 27

most common malignant soft tissue tumor of head and neck in children, males, poor prognosis, radiation therapy, chemotherapy, etc

Answer 27

Rhabdomyosarcoma

Question 28

benign proliferation of capillaries, if small called capillary hemangioma aka strawberry nevus, (contains numerous small capillaries, raised, red, lumpy, area of flesh anywhere in the body), Cavernous hemangioma (contains larger blood vessels). Present at birth, more common in females, may undergo spontaneous remission, can be treated with surgery or injection of sclerosing solution.
benign proliferation of capillaries, if small called capillary hemangioma aka strawberry nevus, (contains numerous small capillaries, raised, red, lumpy, area of flesh anywhere in the body), Cavernous hemangioma (contains larger blood vessels). Present at birth, more common in females, may undergo spontaneous remission, can be treated with surgery or injection of sclerosing solution.

Answer 28

Hemangioma (congenital)

Question 29

pebbly, most commonly located at tip of tongue, dilated lymph vessels.

Answer 29

Lymphangioma (congenital)

Question 30

smooth, grey, spontaneously bleeds to touch. malignant vascular tumor

Answer 30

Angiosarcoma

Question 31

2nd most common aids related neoplasm, once rare now, may arise in multiple sites due to HIV/AIDS, including skin and oral mucosa, more aggressive form with HIV, lesions are red/purple macules, plaques, or exophytic tumors. Malignant vascular tumor

Answer 31

Kaposi sarcoma

Question 32

aka mole, tan to brown macules or papules, mostly on hard palate and buccal mucosa, occurs more often in females, identified in childhood, and increase in numbers in individuals between 20-50 years of age. Benign, may transform to malignancy, if unknown cause, duration, or recent onset, treated with biopsy, excision, and recurrence is rare.

Answer 32

Melanocytic nevi