Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Oral Pathology > Ch 7 Neoplasia > Flashcards

Ch 7 Neoplasia Flashcards

1
Q

New growth. Uncontrolled proliferation of new cells

A

Neoplasia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Mass of new cells. Growth controlled and progressive

A

Neoplasm

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Study of tumors or neoplasms

A

Oncology

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Occurring outside of bone

A

Peripheral

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Not malignant. Favorable for recovery. Gen slow growing

A

Benign

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Malignant tumor (neoplasm) of epithelium

A

Carcinoma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Occurring within bone

A

Central

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Disordered growth or organization of cells (no uniform look)
Characteristic of malignant

A

Dysplasia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Surrounded by capsule of fibrous CT
Characteristic of benign

A

Encapsulated

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Abnormal increase in # of the normal arrangement of tissue

A

Hyperplasia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Antibody

A

Immunoglobin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Confined to site of origin without invasion of neighboring tissues

A

In situ

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Infiltration and active destruction of surrounding tissues
(Prerequ for metastasis)

A

Invasion

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

White plaque like lesion of oral mucosa that can’t be wiped off and can’t be diagnosed as any other disease

A

Leukoplakia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Likely to cause death of host (tumor=resistant to tx)

A

Malignant

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Transport of tumor cells to other parts of body. Removal from primary tumor

A

Metastasis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

OG site of tumor. Site of metastasis

A

Primary tumor

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

Malignant tumor of CT

Less common but more deadly than carcinoma

A

Sarcoma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Neoplasm, also swelling or enlargement

A

Tumor

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

Absence of normal differentiation
Anaplasia
Characteristic of some malignant tumors

A

Undifferentiated

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

New growth
Cells exhibit uncontrolled proliferation (&unlimited)
Abnormal process

A

Neoplasia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

4 Stages of Neoplasia

A
  1. Irreversible change takes place in CELLS
  2. Passed on to NEW CELLS
  3. Results in UNCONTROLLED CELL MULTIPLICATION
  4. Not controlled by process in body that maintains SIZE of normal tissues
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

Causes of neoplasia (4)

A

Chemicals
Genetic mutation
Radiation (sun, X-rays, nuclear accident)
Oncogenic viruses (cause tumor)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

Benign or malignant ?

Usually well differentiated
Slow growing
Encapsulated (walled off by surrounding CT)
No metastasis (localized)

A

Benign

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
Q

Benign or malignant

Well to poorly defined
Slow to rapid growth
Invasive and encapsulated
Metastasis likely

A

Malignant

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
26
Q

Malignant tumors are… (4)
PPHA

A

Poorly differentiated (do not resemble normal cells they originate from)

Pleomorphic cells (vary in size and shape)

Hyper chromatic nuclei (darker than those of normal cells)

Abnormal mitosis (abnormal miotic shapes)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
27
Q

Oma = _______

A

Tumor

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
28
Q

Benign fat tumor

A

Lipoma

29
Q

Malignant tumor of epithelium

A

Carcinoma

30
Q

Malignant tumor of squamous epithelium

A

Squamous cell carcinoma

31
Q

Malignant tumor of bone forming tissue

A

Osteosarcoma

32
Q

Benign tumor of bone

A

Osteoma

33
Q

Nevus is tumor of ____ producing cells

A

Melanin

34
Q

What kind of tumor of squamous epithelium? Benign or malignant?

Small outward growing
Pedunculated or sessile
Numerous papillary projections (white or color of mucosa)
Cauliflower like
Color depends on amount of surface keratin
Looks like common wart

Loc anywhere in moths
Tx surgery, base removed
Prog lesion usually don t recur

A

Papilloma

35
Q

Premalignant lesions. Leukoplakia or Erythroplakia

White plaque like can’t be rubbed off
Usually due to hyperkeratosis
Can be squamous cell carcinoma (FOM, lips, ventrolateral tongue)

Smooth red patch or granular and velvety
Less common
90% SSC or epithelial dysplasia (one or more found is cause for concern)
Loc : FOM, tongue, soft palate

Lesion, mix of red and white areas, variation
of Erythroplakia “salt and pepper”

A

Leukoplakia

Erythroplakia

Speckled Leukoplakia

36
Q

Malignant of squamous epithelium
Ulcer that won’t heal!
Most common primary malignancy of oral cavity
Can infiltrate adjacent tissues and metastasize to lymph nodes of neck than to distant sites
#1 cause is smoking and chemicals such as alcohol

Loc anywhere in mouth but most common
-FOM, ventrolateral tongue, soft palate, Tonsillar pillar, retromolar pad
Clinically outward growing ulcerative mass, early tumor
Histology cells invade through basement membrane into underlying CT

A

Squamous Cell Carcinoma

37
Q

Type of squamous cell carcinoma
Vermillion of lips, skin of face
Histology degeneration of collagen and epithelial dysplasia
Prog much better than SCC of oral mucosa
Clinically color of v border changes from dark pink to uniform mottled grayish pink
Interface of border and skin is blurred

A

Solar cheilitis
Actinic cheilitis

38
Q

Age group most effected by SSC

Most important risk factor of SSC

A

Pts over 40
Men out numbered women but women catching up (increase smoking in women)

Use of tobacco
Smoking, cigars, pipes, spit, etc
Use of alcohol in conjunction with smoking increases risk

39
Q

Tx of SSC

Prognosis

A

Indiv or combo of
Rad
Chemo
Surgery

Size and location of tumor (father from bloodstream the better)
Metastasis. Distance from primary site (if to cervial lymph nodes is bad prognosis)
Location of lesion (better on lips/skin not oral)

40
Q

Tumor less than 2cm
No palpable nodes
No distant metastasis

A

Stage 1

41
Q

2-4cm
No palpable nodes
No distant metastasis

A

Stage 2

42
Q

> 4cm, no palpable nodes, no distant metastasis

> 4cm, ipsilateral palpable nodes, no distant metastasis

<2cm or 2-4cm, with ipsilateral palpable nodes and no distant metastasis

A

Stage 3

43
Q

<2cm, 2-4cm, or >4cm with contralateral or bilateral nodes (or fixed palpable), no distant metastasis

<2cm, fixed palpable nodes, no distant metastasis

Tumor invades adjacent tissues, no palpable nodes, no distant metastasis

Any pt w clinical or rad evidence of metastasis

A

Stage 4

44
Q

Form of SCC
Better prognosis, usually doesn’t metastasize (if not tx can cause localized damage)
Appearance is slow, outward growth w pebbly white and red surface
Does not invade underlying tissue

Tx surgical excision

A

Verrucous Carcinoma

45
Q

Malignant skin tumor made up of epithelial basal cells (deepest layer)
Etiology-sun exposure
Clinically - non healing ulcers of skin, rolled borders
Location: face, not oral cavity. Rarely metastasizes
(Refer to dermatologist if does not heal in 10 days)

Tx surgery

A

Basal Cell Carcinoma

46
Q

Most common areas of salivary gland tumors

A

Jxn of hard and soft palate, retromolar pad, labial buccal mucosa, FOM, upper lip

47
Q

Adenomas is _____ tumor and its source is

A

Benign
Glandular epithelium

48
Q

Adenocarinomas is _____ tumor and source is

A

Malignant
Modified specialized epithelium tissues w salivary glands

49
Q

Benign salivary gland tumor (mixed tumor, epi and CT)
Most common 90%

Loc palate or parotid gland
Clinically slow enlarging non ulcerated painless and dome shaped mass
Tx and Prog surgical can undergo metastasis and be difficult to remove
Part of parotid gland removed in case of tumors

A

Pleomorphic Adenoma

50
Q

Salivary Gland Tumors

1 type, secretory, benign
Several cells inside, slice cyst for biopsy, malignant
Seem more in children, parotid or palate, malignant

A

Monomorphic adenoma

Adenoid cystic carcinoma

Mucoepidermoid carcinoma

51
Q

Derived from tooth forming tissues
Benign but locally aggressive

A

Odontogenic tumors

52
Q

Proliferation of ameloblasts

Loc-
max and Mandibular
unencapsulated
Extensive in max-into vital structures (brain)
80% of mand area (molar) can cause bone expansion

Rad-
Honeycomb, soap bubble
Tx- complete surgical excision, recurrence common

A

Ameloblastoma

53
Q

Cementum producing lesion, fused on root
Rad- well defined RO mass, continuous w root, can cover apex and surround by RL halo

Tx- enucleation of tumor and removal of involved tooth

A

Benign Cementoblastoma

54
Q

Most common clinical manifestation is failure of perm tooth to erupt
Composed of mature enamel, dentin, cementum and pulp
Most common odontogenic tumor
2 types compound and complex

A

Odontoma

55
Q

Collection of numerous small teeth (distinct mini teeth in cluster)
More common anterior maxillary

Rad cluster of mini teeth surrounded by RL halo

A

Compound Odontoma

56
Q

Mass of enamel dentin cementum and pulp, doesn’t resemble normal teeth
Common is posterior Mandibular
Rad- RO mass surrounded by RL halo

(Dental soup all mixed and no distinction)

A

Complex Odontoma

57
Q

Well demarcated sessile or pedunculated lesion
Originates in interdental papilla
Composed of fibrous CT w scatted bone and cementum calcifications

Tx surgery thorough scaling of adjacent teeth

A

Peripheral Ossifying Fibroma

58
Q

Benign tumor of mature fat cells
Yellowish mass w thin epithelium overlying it
Bc of epithelium, boood vessels seen on surface

A

Lipoma

59
Q

Benign proliferation of capillaries
Common not really tumor present at birth
Clinically deep red blanch when pressure applied
2 kinds capillary hem (numerous small capillaries) and cavernous hem. (Larger bvs)
Loc more than 1/2 occur in head and neck area tongue (can lead to macroglossia)
Tx possible spontaneous remission, surg, or injection of sclerosing agent

A

Hemangioma

60
Q

Benign tumor of lymphatic vessels
Most present at birth, 1/2 head and neck area
Most common site is tongue
Tx surgical excision (tend to recur)

A

Lymphangioma

61
Q

Benign tumor of melanocytes
Can be pigmented congenital lesion
Loc- skin or oral cavity (hard palate or buccal mucosa)
Clinically tan brown macula or papule
Pigmented with ulcerations or increases size or change of color may = malignant
Tx- biopsy if unknown cause, duration or recent onset
Surg excision

A

Nevus

62
Q

Malignant tumor of melanocytes
Etiology sun exposure, rare for primary in oral cavity usually on skin then metastasize to OC
Appears rapidly enlarging bluish to black mass
Loc palate or max gingiva
Tx surg or chemo
Prog poor

A

Malignant Melanoma

63
Q

Torus, exostosis, osteoma (benign tumor or mature normal compact bone) are what

A

Tumors of bone and cartilage

64
Q

Malignant tumor of bine forming tissue
Diffuse swelling or mass can be painful
Parasthesia of lip can occur is mandible involved

Prog only 20% of pts w OS of jaws survive

A

Osteosarcoma

65
Q

Benign tumor of cartilage

Malignant tumor of cartilage (rare but deadly, 30% pts invoking jaws survive)

A

Chondroma

Chondrosarcoma

66
Q

Overproduction of atypical WBCs ( profilerate in bone marrow and spill into circulating blood and tissues )

Acute (common children and YAs, proliferation of immature blood cells) and chronic (middle aged adults, prolif mature WBC)

Tx chemo, rad and corticosteroids
Prog depends on extend of disease

Diffuse gingival enlargement and persistent bleeding

A

Leukemia

67
Q

Malignant tumor of lymphoid tissue
Gradual enlargement of involved lymph nodes. Orally is Tonsillar area (palatine in particular)

A

Non Hodgkin’s lymphoma

68
Q

Ex: Jaw malignancy from breast cancer (if biopsy taken would be similar to breast cancer)
Rare but usually found on mandible if so and appears several years later after primary lesion discovered

Rad poorly defined RL

Advanced and Prog is poor

A

Metastatic tumors of jaw

Oral Pathology (3 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions