CH 6 CHALLENGES TO EFFECTIVE DRUG THERAPY Flashcards
- A nurse is preparing a drug for administration to a patient. The drug does not have an indicated use for the patient’s medical diagnosis. What should the nurse do?
A) Administer the drug as ordered.
B) Question the prescriber concerning the ordered drug.
C) Ask a coworker his or her thoughts about the ordered drug for the patient.
D) Ask the patient why the drug has been prescribed for him or her.
Ans: B
Feedback:
If the nurse is not sure about giving a drug, the order should be questioned. The nurse should never give a medication that is not clear. Mistakes do happen and the drug ordered, if not approved for the condition that the patient has, could be an error on someone’s part. The person who wrote the order should be questioned, not a co worker, who probably does not know why an off-label drug is being used. It would be unprofessional and inappropriate to ask the patient about the drug.
- According to Center for Disease Control and Prevention (CDC) recommendations, what is the role of the nurse in preparing for the possibility of bioterrorism?
A) Post updated information on signs and symptoms of infections caused by
biological agents
B) Provide guidelines for treating patients exposed to, or potentially exposed to,
biological agents
C) Remain current on recognition and treatment of infections caused by biological
weapons
D) Advocate for increased funding for research involving bioterrorism and patient
treatment
Ans: C
Feedback:
Nurses need to remain current about recognition of and treatment for those exposed to biological weapons because nurses are often called upon to answer questions, reassure the public, offer educational programs, and serve on emergency preparedness committees. The CDC posts updated information on signs and symptoms of infections caused by biological agents that nurses would read. The CDC also provides guidelines for how to treat patients exposed to biological agents and the nurse must remain current on this information. Although nurses could advocate for funding, this is not usually the role of the nurse.
- How can the nurse find the most up-to-date information about emergency preparedness related to bioterrorism agents?
A) Read textbooks devoted to the topic.
B) Ask coworkers to explain current events.
C) Read journal articles about bioterrorism agents.
D) Visit the Centers for Disease Control and Prevention (CDC) Web site.
Ans: D
Feedback:
The most current information will be found on the CDC Web site because new information can be posted immediately whereas textbooks and journal articles take time to print. Coworkers may or may not remain current on emergency preparedness and should not be the primary source of information.
- The nurse is assessing a diabetic patient who has presented at the clinic reporting several hypoglycemic episodes during the past 3 weeks. The nurse questions the patient about the use of herbal or alternative therapies, suspecting what herbal remedy could cause the hypoglycemic episodes?
A) St. John’s wort
B) Kava
C) Fish oil
D) Ginseng
Ans: D
Feedback:
Ginseng is known to decrease blood sugar levels. If the patient used this in combination with his or her oral antidiabetic agent, diet, and exercise, his or her blood sugar could drop below therapeutic levels. St. John’s wort interacts with many drugs, but not with antidiabetic agents. Kava is associated with liver toxicity. Fish oil has been associated with decreased coronary artery disease.
- A 22-year-old patient calls the clinic and tells the nurse that she has been depressed and is thinking about taking St. John’s wort but wants to know if it is safe first. The nurse begins by questioning what other medications the patient takes and would be concerned about a drug-alternative drug interaction if the patient is also taking what type of medication?
A) Antihistamines
B) Analgesics
C) Antibiotics
D) Oral contraceptives
Ans: D
Feedback:
St. John’s wort can interact with oral contraceptives that alter drug metabolism, which can decrease the effectiveness of the contraceptive. Analgesics, antibiotics, and antihistamines can be taken in combination with St. John’s wort without known adverse effects.
- A patient tells the clinic nurse that he or she has been taking over-the-counter (OTC) Pepcid to relieve acid indigestion for several years. This is the first time the patient has ever reported this issue to a health care provider. As part of the teaching plan for this patient, the nurse explains what risk associated with not sharing OTC drug use with the provider?
A) The OTC drug could be more expensive than seeking health care advice.
B) The drug could mask symptoms of a serious problem that is undiagnosed.
C) Use of the drug could cause a rebound effect of Pepcid.
D) The drug could interact with several cold medicines.
Ans: D
Feedback:
OTC drugs allow patients to self-diagnose and treat routine signs and symptoms without seeing a health care provider. This self-prescribed treatment, however, could mask a more serious underlying medical problem and result in a poor outcome for the patient. The issues of drug rebound and drug interaction need to be considered, but the safety issue related to self-diagnosis and self-prescription presents the greatest risk to the patient. Patients should always be encouraged to discuss the use of OTC products with their health care provider.
- What patient populations would the nurse expect is most likely to be prescribed a drug for an off-label use?
A) Adolescent and middle-aged adult patients
B) Patients with diabetes or heart disease
C) Obstetric and neonatal patients
D) Pediatric and geriatric patients
Ans: D
Feedback:
Drugs being used for an off-label purpose are commonly prescribed for pediatric and geriatric populations due to the lack of drug trial information and minimal premarket testing. Often a trial-and-error method is used in treating both the pediatric and geriatric populations when only adult information is known. The geriatric population responds to medication more like children because of their decreased ability to metabolize medications. Adolescents, especially later adolescents, use medications similarly to young adults as do middle-aged adults. Patients with different diagnoses are often involved in drug testing including those with diabetes and heart disease. Drugs are discouraged for use in obstetric patients.
- A patient calls the clinic and asks to speak to a nurse. The patient questions the nurse about the use of a drug that was advertised on TV. The patient tells the nurse he or she is sure that the drug will make him or her feel the same way as described in the commercial. What response is most appropriate for the nurse to make?
A) “I’m glad that you want to be involved in treatment decisions but you are not qualified to decide what medications are best for your condition.”
B) “It’s important to remember that drug advertisements emphasize the positive effects of drug therapy and not the adverse effects or contraindications.”
C) “You need to remember that the drugs being advertised are much more expensive than other drugs that have the same effect.”
D) “I’ve seen those advertisements and I would want to take that medication too if I had the condition it was designed to treat.”
Ans: B
Feedback:
It would be important for the nurse to remind the patient that advertisements always emphasize the positive effects of drug therapy. The patient should not be discouraged from contributing to the plan of care by being told she is not adequately qualified to make decisions because no one is more qualified to make decisions about her own body. Although the drug may be more expensive, this is not a reason to choose or avoid a medication that could be more effective. Agreeing with the patient is not meeting the nurse’s obligation to teach and inform.
- The clinic nurse is talking with a patient about information concerning a drug her or she bought online. What is the nurse’s responsibility to the patient concerning this information?
A) Encourage the patient to seek information about drugs from a pharmacist.
B) Explain that information obtained from the Internet is not always accurate.
C) Offer the patient a drug reference guide to read and learn more about the drug.
D) Interpret the information and explain it in terms that the patient will understand.
Ans: D
Feedback:
The Internet can be a good reference for drug information. However, the amount and reliability of the information can be overwhelming. The nurse should always try to interpret the information and explain it in terms that the patient will understand. A pharmacist is a good resource person but may not be able to teach from a holistic perspective. Drug reference guides may be hard for the patient to understand and he or she would still need someone to interpret the information.
- The triage nurse in the emergency department sees a patient suspected of abusing amphetamines brought in by friends. While assessing this patient, what would the nurse be likely to find if steroids are being abused?
A) Hypertension
B) Bradycardia
C) Drowsiness
D) Elated mood
Ans: A
Feedback:
Increases in blood pressure, tachycardia, and insomnia are symptoms of amphetamine abuse. Elation can indicate abuse of cannabis.
- The nursing instructor is discussing the off-label use of drugs. What group of drugs would the instructor tell the nursing students is often used for off-label indications?
A) Drugs used to treat psychiatric problems
B) Drugs used to treat gastrointestinal (GI) problems
C) Drugs used to treat cardiovascular problems
D) Drugs used to treat musculoskeletal problems
Ans: A
Feedback:
Drugs often used for off-label indications include the drugs used to treat various psychiatric problems. Drugs used to treat GI, cardiovascular, or musculoskeletal problems do not fall in the category of frequent off-label uses.
- The patient calls the clinic nurse and says, “I looked this medication up on the Internet after it was prescribed yesterday and there is nothing in the literature about this drug being used to treat my disorder. Should I still take it?” What is the nurse’s best response?
A) “No, stop taking it immediately until I can consult with the doctor because it is obvious a mistake was made.”
B) “Oh, that’s okay. Go ahead and take it because the doctor wouldn’t order it if he or she didn’t think it would be effective.”
C) “It is quite common for drugs to be found to have positive effects for a condition not originally intended so it is safe to take.”
D) “Let me talk with the physician about why this medication was ordered for you and I will call you back.”
Ans: D
Feedback:
Off-label use is relatively common because new information is gathered when the drug is used by large numbers of people that may indicate another condition for which the drug is effective. However, if the nurse does not know for a fact that the drug prescribed is the right drug for the patient’s condition, it is always best to consult with the prescriber to make sure the patient is taking the right drug and to avoid a medication error. The medication may be perfectly safe so the patient should not be told the doctor made a mistake.
- When a drug is ordered off-label, what must the nurse be clear about before administering the drug? (Select all that apply.)
A) Why the drug is being given B) Its potential for problems C) The research that has been done D) The age group it was pretested on E) The intended use
Ans: A, B, E
Feedback:
Liability issues surrounding many of these uses are very unclear, and the nurse should be clear about the intended use, why the drug is being given, and its potential for problems. Knowing the age group it was pretested on and knowing the research that has been done are not factors the nurse needs to know before administering the drug.
- It is important for the nurse to be aware of what related to the way drugs are marketed?
A) The adverse effects the advertisements do not mention
B) What magazines and Web sites contain the advertisement
C) What patients are seeing in the advertisements about these drugs
D) The name of the cheerful, happy models who are advertising these drugs
Ans: C
Feedback:
As the marketing power for prescription drugs continues to grow, the nurse must be constantly aware of what patients are seeing, what the ads are claiming, and the real data behind the indications and contraindications for these “hot” drugs. The Food and Drug Administration regulates the information that needs to be contained within medication ads. Where the patient saw the ad and the actors in the ads are unimportant.
- When evaluating information accessed over the Internet, an important question the nurse should teach the patient to ask is what?
A) Is the information anecdotal?
B) Where has this information been obtained?
C) Is this information paid for by the drug company?
D) How many patients have had input into the information?
Ans: A
Feedback:
Many people do not know how to evaluate the drug-related information that they can access over the Internet. Is it accurate or anecdotal is an important concept for the nurse to teach the patient to assess to verify the accuracy of the information. Where the information came from is unimportant. It would be expected that all drug advertising is paid for by the drug company and this is not an important concern. Number of patients with input into the information is most likely none because information is gathered from health care professionals.