Ch. 505.1 - Hemangiomas Flashcards
MC benign tumors of infancy
Hemangiomas
Hemangiomas: Girls vs Boys
Girls
The risk of hemangioma is doubled in ___ and 10 times higher in offspring of women who had ___
Premature infants; chorionic villus sampling
Hemangiomas grow rapidly during ___ with slowing of growth in the next ___ and involution by ___
1 yr, 5yra, 10-15yrs
More than 50% of all hemangiomas are located in the
Head and neck region
Most hemangiomas are multiple vs single
Single
T/F The presence of more than 1 cutaneous lesion (hemangioma) increases the likelihood of visceral hemangioma
T
Hemangioma: Primary site of visceral involvement
Liver
T/F Most hemangiomas require no therapy
T
Approx ___% of hemangiomas cause impairment and ___% are life threatening because of their location
10, 1
___ is a syndrome characterized by a rapidly enlarging hemangioma, thrombocytopenia, microangiopathic hemolytic anemia, and coagulopathy
Kasabach-Merritt syndrome
T/F Kasabach-Meritt syndrome is associated with infantile hemangiomas
F
T/F The presence of a midline hemangioma in the lumbosacral area indicates the need for an MRI to search for underlying asymptomatic neurologic abnormalities
T
An ultrasonographic scan or MRI of the ___ should be performed if multiple cutaneous lesions are present.
Liver
MC tumor of infancy
Infantile hemangiomas
Risk factors for infantile hemangioma
1) LBW 2) Female 3) Prematurity 4) White race
Immunohistochemical marker specifically expressed in infantile hemangiomas which helps distinguish it histologically from other vascular anomalies
GLUT-1
Presenting signs of a developing hemangioma
1) Erythematous/blue/pale area 2) Ulceration of the perineum or lip
Favored sites of hemangioma
Face, scalp, back, anterior chest
