Ch. 50- Acid Controlling Drugs Flashcards
Chief cells
cells in the stomach that secrete the gastric enzyme pepsinogen
Gastric glands
secretory glands in the stomach containing the following cell types: parietal, chief, mucous, endocrine, and enterochromaffin
Hydrochloric Acid (HCl)
an acid secreted by parietal cells in the lining of the stomach that maintains the environment of the stomach at a pH of 1-4
mucous cells (aka surface epithelial cells)
cells whose function in the system is to secrete mucous that serves as a protective mucous coat against the digestive properties of HCl.
parietal cells
cells in the stomach that produce HCl. These cells are the primary site of action for many of the drugs used to treat acid-related disorders
pepsin
an enzyme in the stomach that breaks down proteins
Antacids drugs
aluminum hydroxide (Amphojel), aluminum hydroxide/magnesium hydroxide (Maalox, Mylanta), calcium carbonate (Tums), magnesium hydroxide (milk of magnesia)
H2 receptor antagonists
cimetidine (Tagamet [HB]), famotidine (Pepcid [AC]), ranitidine (Zantac)
Protein Pump Inhibitors (PPIs)
lansoprazole (Prevacid), omeprazole (Prilosec), pantoprazol (Protonix)
Miscel. drugs
sucralfate (Carafate), misoprostol (Cytotec), simethicone (Mylicon)
Antacids
basic compounds composed of different combinations of acid-neutralizing ionic salts