Ch 5 - EN and PN Flashcards
EN
Feeding provided through the GI tract via a tube, catheter or stoma that delivers nutrients distal to the oral cavity
PN
intravenous administration of nutrients
EN Advantages
o Intake easily/accurately monitored
o Increased compliance with intake
o Provides nutrition when oral is not possible or accurate
o Costs less than parenteral nutrition
o Supplies readily available
o Preserves gut integrity – better GI barrier function
o ↓ likelihood of bacterial translocation
o Preserves immunologic function of gut → preserves gut-associated lymphoid tissue (GALT) activity
o ↓ rates of infection unrelated to GI tract
EN Disadvantages
o Potential Complications • Tube displacement, obstruction or clog • Contamination of formula • GI complications o Costs more than oral diets o Less “palatable / normal” o More labor intensive
Which Patients Need EN?
- Impaired ingestion
- inability to consume adequate oral nutrition
- impaired digestion, absorption, metabolism
- severe wasting or depressed growth
Impaired ingestion (EN)
- Neurologic disorders/comatose state
- Traumatic brain injury
- HIV/AIDS
- Facial trauma
- Oral or esophageal trauma or cancer
- Congenital anomalies
- Respiratory failure
- Cystic fibrosis
Inability to consume enough oral nutrition (EN)
- Hyperemesis of pregnancy
- Hyermetabolic states such as burns
- Anorexia in congestive heart failure, cancer, COPD
- Congenital heart disease
- After orofacial surgery or injury
- Spinal cord injury
Impaired digestion, absorption, metabolism (EN)
- Severe gastroparesis
- Crohn’s Disease
- Short bowel syndrome
- Pancreatitis
- Inborn errors of metabolism
Severe wasting or depressed growth
- Cystic fibrosis
- Failure to thrive
- Cancer
- Critical illness, trauma, burn
- Cerebral palsy
Nasogastric EN
3-4 weeks
Normal GI
Bolus, intermittent or cont.
Nasoduodenal or Nasojejunal EN
3-4 weeks
gastric motility disorders, esophageal reflux or persistent nausea and vomiting
Percutaneous Endoscopic Gastrostomy (PEG) or jejunostomy (PEJ)
nonsurgical
>3-4 weeks
1F (French unit)
1F = 33mm diameter
Standard Formulas (EN)
• Lactose-free, 1kcal/mL
- Over-the-counter supplements
- Formulas designed specifically for tube feeding
• Some have fiber, some don’t
• Concentrated standard formulas: 1.5 – 2 kcal/mL for fluid restriction
High-Nitrogen EN Formulas
burns, fistulas, sepsis, trauma
Chemically-defined EN Formulas
• Some called “elemental”
• Low in fat, supplemented with MCT
- Long term use → EFA deficiency – need to monitor
• Protein fragments: dipeptides, tripeptides or oligopeptides
Disease Specific EN Formulas
- Kidney disease
- Liver disease
- Glucose intolerance/diabetes
- Pulmonary failure
- Immunosuppression
- Wound healing
- Expensive and controversial efficacy
Modular Formulas
- Individual macronutrients
- Protein
- Carbohydrate
- Fat
- Occasionally combination products used
Protein EN
- 10-37% of kcals
- intact versus hydrolyzed affect osmolality
- High-protein
- Glutamine and arginine
Carbohydrates EN
- 30-90% of kcals
- Source and degree of hydrolysis affect osmolality
- Lactose is not used
- Addition of fiber