ch. 5 & 6 short answers Flashcards

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1
Q

explain the 5 step life cycle of animal viruses

A

absorption
penetration
synthesis
assembly
release

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2
Q

absorption

A

virus enters a susceptible host cell and absorbs to receptor sites on cell membrane

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3
Q

penetration/uncoating

A

the entire virus is engulfed by the cell and enclosed in a vacuole/ vesicle

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4
Q

synthesis

A

the viral nucleic acid begins to synthesize the building blocks for new viruses

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5
Q

assembly

A

mature virus particles are constructed from the growing pool of parts. the capsid is laid down as an empty shell that will be receptacle for the nucleic acid strand

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6
Q

release

A

assembled viruses leave their host. non-enveloped viruses that reach maturation in the cell nucleus are released when the cell lyses/ruptures. the nucleocapsid binds to the membrane

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7
Q

lytic bacteriophage infections

A

destroys the host cell

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8
Q

lysogenic conversion

A

when a bacterium acquires a new trait from its temperate phage

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9
Q

what are 3 ways in which viruses are cultivated

A

using live animal inoculation
using bird embryos
using cell (tissue) culture techniques

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10
Q

3 purposes of cultivating viruses

A

isolate and identify viruses in clinical specimens
prepare viruses for vaccines
do detail research on viral structure, multiplication cycles, genetics, and effects on host cells are cultivated

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11
Q

explain why antiviral drugs are difficult to develop and why its advantages to taken in the first 48 hrs of symptoms

A

viruses borrow host proteins and functions to propagate themselves, so it is difficult to find drugs that will help without damage caused to the cell

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12
Q

7 properties of viruses

A
  1. are obligate intracellular parasites of bacteria, protozoa, fungi, algae, plants and animals
  2. are ubiquitous in nature and have had major impact on development of biological life
  3. are NOT cells, structures are very compact and economical
  4. do not dependently fulfill the characteristics of life
  5. basic structure consists of protein shell surrounding nucleic acid core
  6. nucleic acid can be RNA or DNA but NOT both
  7. nucleic acid can be double stranded DNA/RNA or single stranded RNA/DNA
  8. molecules on virus surface give them high specificity for attachment to host cell
  9. multiple by taking control of host cell’s genetic material and regulating the synthesis and assembly of new viruses
    10 . lack enzymes for most metabolic processes
  10. lack machinery for synthesizing proteins
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13
Q

are viruses dead or alive? explain fully.

A

there are two viewpoints about this question: one says that since they can’t reproduce independently from the host cell, then they are not living and they should be call infectious molecules.
the other viewpoint is that even thought they don’t have most life processes the viruses can direct them and they are more inert and lifeless molecules

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14
Q

3 DNA viruses

A

2 stranded:
variola virus: small pox
herpes simplex 2: genital herpes
single stranded:
parvovirus: erythema infection

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15
Q

4 RNA viruses

A

single stranded
(+) poliovirus: poliomyelitis
(-) influenza virus: influenza
HIV: AIDS
double stranded:
rotavirus: gastroenteritis

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16
Q

prions

A

distinct protein fibrils in the brain tissues and the agents

17
Q

prions diseases

A

creutzfeldt- jakob disease: infiltrate the CNS of humans and causes gradual degeneration and death
bovine spongiform encephalopathy: contaminated beef
shy drager syndrome/ multiple system atrophy: resembles Parkinson’s disease, accumulation of alpha-synuclein in the brain

18
Q

autotrophs

A

get their energy from CO2- get energy from sunlight and chemical reactions

19
Q

photoautotrophs

A

they capture energy and transform it into chemical energy that can be used in celll metabolism

20
Q

chemoautotrophs

A

organic compounds for energy and inorganic compounds as a carbon source

21
Q

lithoautotrophs

A

rely totally on inorganic minerals: derive energy in diverse ways like removing electrons from inorganic substrates like hydrogen gas, sulfide, sulfur, or ion and then combine then w/ CO2 and hydrogen

22
Q

chemoheterotrophs

A

derive their carbon & energy from organic compounds; they process by cell respiration/ fermentation releasing energy in the form of ATP

23
Q

saprobes

A

free living that feed primarily on organic detritus from dead organism

24
Q

parasites

A

derive nutrients from the cells of a living host

25
Q

isotonic solution

A

w/ cell wall: water concentration is equal all around, diffusion rates are equal
w/o cell wall: diffusion rates are equal in both directions

26
Q

hypotonic solution

A

w/ cell wall: diffusion of water is in the cell, swells the protoplast