CH 4 Pediatric Pulmonary physiology and pathophysiology Flashcards

1
Q

Pediatric ECMO is defined as an age group of ?

A

> 30 days of life

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2
Q

What are the 3 most common reasons that pediatrics require ECLS ?

A

Viral Pneumonia
Bacterial Pneumonia
Aspiration Pneumonia

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3
Q

What is the most common diagnosis for the pediatric pulmonary group ?

A

Viral Pneumonia

accounts for 90% of pneumonia cases in children, & 4 - 39% in the adults.

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4
Q

The combination of what two things interrupts the gas exchange capability of the lungs during viral pneumonia?

A
  1. ) Cellular Destruction

2. ) Fluid filled alveoli

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5
Q

Viral pneumonias are caused by ?

A

Influenze types A,B,C

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6
Q

What virus is most common in infants and young children?

A

Repiratory Syncytial Virus

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7
Q

What are 6 comlications of viral pneumonia ?

A
Superimposed bacterial infections
Respiratory failure
Pulmonary Fibrosis
ARDS
Noncardiogenic pulmonary edema
Reyes Syndrome
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8
Q

Viral pneumonia usually has good prognosis but death can occur with what viruses in the pediatric and elderly populations?

A
  • Adenovirus

- Influenza Infections

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9
Q

What are the most common conditions in sepsis that may require ECMO ?

A
  • ARDS

- Bacterial Pneumonia

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10
Q

Acute bacterial infection in the lung parynchyma that causes severe inflammatory response that fills the alveoli and prevents them from exchanging gas normally ?

A

Bacterial Pneumonia

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11
Q

What are the two most common bacteria that would necessitate ECMO ?

A
  • Staphylococcus Aureus

- Beta-Hemolytic Streptococci (GBS)

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12
Q

Some centers have reported that they have controlled severe bleeding without having thrombosis within the ECMO circuit by doing what?

A

Factor VII administration

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13
Q

What is the most common bacterial pneumonia ?

A

Streptococcus pneumonia

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14
Q

Empyema definition ?

A

Pus collection in the lungs

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15
Q

Severity of hypoxemia in ARDS is calculated by?

A

PaO2/FiO2 ratio less than 200

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16
Q

Severity of hypoxemia due to an Acute Lung Injury is calculated by?

A

PaO2/FiO2 ratio less than 300

17
Q

How would you exclude cardiogenic pulmonary edema while making a diagnosis of ARDS ?

A
  • Clinical Criteria

- PCWP

18
Q

What are the 2 types of alveolar epithelial cells that exist?

A

Type I = 90% of alveolar epithelium

Type II = Produce surfactant, ion transport, proliferation, differentiation into type I after cell injury.

19
Q

Damage to Type II alveolar epithelial cells results in what ?

A

Decreased production of surfactant
Decreased compliance
Alveolar collapse