1
Q

T/F: The plasma membrane is permeable to any type of molecule.

A

False! The plasma membrane is selectively permeable.

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2
Q

Random molecular movement of substances through the membrane either through a channel or pore.

A

Passive transport

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3
Q

What is the energy source for diffusion?

A

Kinetic energy of matter; substances tend to move along the gradient from greater concentration to areas of lesser concentration

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4
Q

Define active transport.

A

Transport across a cell membrane that occurs against its electrochemical or concentration gradient and requires the use of ATP.

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5
Q

What is the difference between diffusion and osmosis?

A

Diffusion is the random motion of particles and their tendency to move from areas of higher concentration to lower; osmosis is the movement of water through a semipermeable membrane in the presence of a concentration difference

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6
Q

Define osmolarity.

A

Total concentration of all solute particles in a solution.

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7
Q

Hydrostatic pressure

A

Pressure exerted by water against its surrounding membrane

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8
Q

A hypertonic solution will cause a cell to:

A

lose water and shrink

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9
Q

A hypotonic solution will cause a cell to:

A

swell

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10
Q

How is filtration different from diffusion?

A

Filtration: water and solutes forced through membrane by hydrostatic pressure, rather than by the kinetic forces of molecular motion and the effects of concentration gradients.

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11
Q

What types of substances most easily diffuse through the cell membrane?

A

Lipid soluble molecules, such as oxygen, nitrogen, carbon dioxide, alcohols

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12
Q

T/F: thicker cell membrane=slower rate of diffusion

A

TRUE!

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13
Q

How does temperature effect rate of diffusion?

A

Higher temp=greater rate of diffusion

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14
Q

How does molecular weight effect rate of diffusion?

A

Greater molecular weight=greater resistance, i.e. slower diffusion

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15
Q

T/F: protein pores are selectively permeable to certain substances

A

FALSE! Well, unless a molecule is too big to pass through. Otherwise, they are open for passage. Protein channels, on the other hand, are selectively permeable and/or gated, regulated by electrical signals or chemical binding.

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16
Q

What type of gate is activated by a change in electrical potential across cell membrane?

A

Voltage gated protein channel

17
Q

Define a ligand gated protein channel

A

Protein channel opened by the binding of a chemical substance (a ligand) with the protein.

18
Q

Give an example of ligand gating in the propagation of nerve signals.

A

Acetylcholine: ACh opens gate of this channel, allows positively charged ions (Na+, K+, Ca2+) to enter to elicit further APs or trigger muscle contraction.

19
Q

Sodium-Potassium Pump: List substances transported, direction of transport, and amount of each

A

3 Na+ ions out of cell; 2 K+ ions into cell

20
Q

Major function(s) of Na+K+ pump

A

Maintains concentration differences across the cell membrane; establishes a negative electrical voltage inside the cell (electrogenic); basis for nerve function and nerve signal transmission; controlling cell volume (preventing too much water from entering the cell when there is a high presence of solute in the cell)

21
Q

Calcium Pump: type of transport, function

A

Primary active transport; pumps calcium out of the cell; homeostatic function (maintain low intracellular Ca2+ level)

22
Q

Coupling mechanism in which more than one substance are carried across the cell membrane

A

co-transport

23
Q

Which secondary active transport method involves 1 ion entering and 1 ion leaving the cell simultaneously?

A

Counter-transport

24
Q

Name the secondary active transport method by which glucose can enter a cell utilizing the transport of ANOTHER ion.

A

Co-transport: transport carrier protein has 2 binding sites, one for sodium and one for glucose; concentration of Na+ outside the cell provides a gradient/energy for transport to occur

25
Q

What are 2 examples of substances that co-transport with Na+?

A

Amino acids and glucose

26
Q

What is a general rule for predicting the behavior or water in the presence of solutes across a semi permeable membrane (osmosis)

A

“water follows salt”

27
Q

Explain osmotic pressure

A

The exact amount of pressure required to stop osmosis. “Resistance” to the flow of water through a semi permeable membrane that is sufficient to stop the movement of water.

28
Q

What are 3 types of gradient that can exist across a cell membrane?

A

Concentration difference of molecules, electrical (charge) difference, and pressure difference across a cell membrane may contribute to an electrochemical gradient.