Ch. 36 & 38 Flashcards
seizure (defined)
abnormal, sudden, excessive, uncontrolled electrical discharge of neurons within the brain; may result in alteration in consciousness, motor or sensory ability, and/or behavior
epilepsy (defined)
- two or more seizures experienced without a known cause (ie fever, tumor)
- chronic disorder with recurrent, unprovoked seizure activity, may be caused by abnormality in electrical neuronal activity and/or imbalance of neurotransmitters (ie GABA)
how is epilepsy quantified (r/t # of seizures)
two or more seizures experienced without a known cause (ie fever, tumor)
types of seizures
- generalized
- partial
- unclassified
- primary or idiopathic epilepsy
- secondary seizures
generalized seizures
tonic-clonic/grand mal
- postictal state ( period of confusion immediately following seizure, then pt is fine)
partial seizures
focal/local
- one cerebral hemisphere- complex or single
unclassified seizures
seizures that can’t be classified due to lack of information
- not witnessed
- no EEG available
primary aka idiopathic epilepsy
- not associated with any identifiable brain lesion
- we don’t know why it happens
secondary seizures
- result from an underlying brain lesion, most commonly a tumor or trauma
- many diseases/disorders associated with s/s of seizure
causes of seizures/ things that increase risk of seizure
- metabolic d/o: liver disease- ammonia goes up, brain swelling
- acute alcohol withdrawal!*
- electrolyte disturbances: low sodium
- heart disease: v-tach
- high fever: common with kids
- stroke: from increased ICP with brain swelling
- substance abuse: need hx of illicit drug use
diagnostics for seizures
- EEG (want to mimic the way pt has a seizure: sleep deprived, no meds, no lotion, clean/clip hair- electrodes to scalp)
- CT/MRI (looking for tumor)
- ID underlying causes (labs, PMH)
- document before and after (want to know how long/length of seizure)
drug therapy “rules” for seizures
- evaluate most current blood level of medication, if appropriate
- be aware of drug-drug and drug-food interactions
- maintain therapeutic blood levels for maximal effectiveness
- do not administer warfarin with phenytoin
- document and report side/adverse effects: fatigue common
phenytoin special considerations
- cannot mix with sugar, ONLY saline
- very small window of therapeutic range- check blood levels!
- no warfarin!
- causes gum hyperplasia
- compliance issue b/c need blood levels checked
seizure medication: AEDs (anti epileptic drugs)
- Carbamazepine: maintenance
- Diazepam: rescue
- Lorazepam: rescue
- Divalproex: maintenance
- Valproic Acid: maintenance
- Gabapentin: maintenance
- Lamotrigine: maintenance
- Levetiracetam: maintenance
- Phenobarbital: maintenance *
- Phenytoin (aka dilantin): maintenance; through IV
patient may be prescribed up to __ medications simultaneously for intractable seizures
patient may be prescribed up to 3 medications simultaneously for intractable seizures
seizure precautions: patient positioning
- turn patient to side if possible
- do NOT force patient to move to side
nursing management when seizure occurs (stages)
- observe and document
- patient safety
- medications
- need medical history to ID why seizure is happening
nursing management when seizure occurs: observe and document
- onset of seizure if witnessed
- behavioral manifestations
- determine if patient is oriented by asking questions and document responses
- document end of seizure
nursing management when seizure occurs: patient safety
- position: side lying
- no restraints
nursing management when seizure occurs: medications
- Lorazepam
- Diazepam
- Diastat
- IV phenytoin
status epilepticus: actions
- establish an airway
- ABGs
- IV push lorazepam, diazepam; rectal diazepam (rescue meds)
-lorazepam is like jelly, insert small amount of NS flush into lorazepam to make easier to draw up - loading dose IV phenytoin (maintenance meds)
what is status epilepticus?
MEDICAL EMERGENCY- loss of neurons may occur (no oxygen to the brain)
- prolonged seizures lasting more than 5 minutes or repeated seizures over the course of 30 minutes
surgical management of seizures
- vagal nerve stimulation (VNS)
- conventional surgical procedures
- anterior temporal lobe resection
- partial corpus callosotomy
surgical management of seizures: VNS
implanted medical device to send electrical impulses to vagus nerve