Ch 34 Drugs Affecting The Upper Respiratory Flashcards
Sinusitis
Occurs when the epithelial lining of the sinus cavities becomes inflamed. Is ca. Be caused by bacteria and viruses.
What is the physiology of the upper respiratory system
It is composed of the nose, mouth, trachea, pharynx, larynx,and the bronchial tree.
Antitussive drugs
Drugs that suppress the cough reflex in many disorders of the upper and lower respiratory tract,including the common cold, sinusitis, pharyngitis and pneumonia they are accompanied by a non productive cough
What is the prototype drug of antitussives
Dextromethorphan
Robitussin, pedis care, vicks44 benylin pediatric
What is dextromethorphan used for
Non productive cough Directly affects the cough center in the medulla Administered orally Metabolized in the liver Excreted in the kidneys
What are contraindications of antitussives
Chronic coughs resulting from emphysema and asthma
You don’t want to supress these coughs be careful in pt with hepatic and renal failure
What are the adverse effects of dextromethorphan
Nausea, vomiting, drowsiness, dizziness, irritability, and restlessness
What are drug interactions of dextromethorphan
MAOI, fluxoxetine, quinidine, and sibutramine