Ch 34 Drugs Affecting The Upper Respiratory Flashcards

0
Q

Sinusitis

A

Occurs when the epithelial lining of the sinus cavities becomes inflamed. Is ca. Be caused by bacteria and viruses.

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1
Q

What is the physiology of the upper respiratory system

A

It is composed of the nose, mouth, trachea, pharynx, larynx,and the bronchial tree.

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2
Q

Antitussive drugs

A

Drugs that suppress the cough reflex in many disorders of the upper and lower respiratory tract,including the common cold, sinusitis, pharyngitis and pneumonia they are accompanied by a non productive cough

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3
Q

What is the prototype drug of antitussives

A

Dextromethorphan

Robitussin, pedis care, vicks44 benylin pediatric

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4
Q

What is dextromethorphan used for

A
Non productive cough
Directly affects the cough center in the medulla
Administered orally
Metabolized in the liver
Excreted in the kidneys
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5
Q

What are contraindications of antitussives

A

Chronic coughs resulting from emphysema and asthma

You don’t want to supress these coughs be careful in pt with hepatic and renal failure

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6
Q

What are the adverse effects of dextromethorphan

A

Nausea, vomiting, drowsiness, dizziness, irritability, and restlessness

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7
Q

What are drug interactions of dextromethorphan

A

MAOI, fluxoxetine, quinidine, and sibutramine

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