Ch. 32 OXYGENATION Flashcards
To achieve the process of R, there must be
1.
2.
3.
- ventilation
- diffusion
- perfusion
The movement of gases between the alveoli in lungs and bloodstream is known as
Diffusion
Movement of blood into and out of the capillary beds surrounding the alveoli to the organs/tissue of the body is known as:
Perfusion
The respiratory system includes the following structures:
1.
2.
3.
- airways and lungs (pulmonary system)
- bony thorax
- respiratory muscles
What are the four components of the upper airway and what is the function?
Nasopharynx, Oropharynx, Laryngopharynx, and Larynx
Function: lined with ciliated mucosa with very rich vascular supply; muscosa lining warms, humidifies, filters inspired air before it passes through to the lungs
This structure connects the upper and lower airways
Larynx
This structure houses the vocal chords
Larynx
The laryngeal box is formed of 3 large cartilages:
- epiglottis
- thyroid
- cricoid
The lower airway consists of these two components:
- conducting airways
- acinus
The conducting airways are part of the _________ airway.
The conducting airways are part of the LOWER airway.
The conducting airways include these four structures:
- trachae
- R/L mainstem bronchi
- secondary bronchi
- brochioles
Is the acinus part of the upper or lower airway?
lower
The acinus are the _____________ units and include these two structures:
The acinus are the GAS EXCHANGE units and include these two structures:
- respiratory bronchioles
- alveoli
Thorax boundaries
- sternum
- 12 ribs
- 12 thoracic vertebrae
Muscles of respiration:
Primary:
1.
2.
Accessory:
1.
2.
3.
Muscles of respiration:
Primary:
- DIAPHRAGM
- INTERCOSTALS
Accessory:
- ABDOMINAL
- STERNOCLEIDOMASTOID
- PECTORAL MUSCLES
Lobes of the lungs (explain why there is a difference R/L)
Right = 3 lobes
Left = 2 lobes (due to proximity to heart)
- The lungs are lined by the ________________
- The chest wall is lined by the ______________
- In between these two layers is called the _____________________
The lungs are lined by the VISCERAL PLEURA
The chest wall is lined by the PARIETAL PLEURA
In between these two layers is called the PLEURAL SPACE
Why does the pleural space have negative pressure?
To prevent lungs from separating from chest wall
What are the key structures in gas exchange?
alveoli
What are pneumocyte II cells and what do they do?
Great alveolar or septal cells manufacture surfactant which acts to lower the surface tension of the alveoli and prevent collapse of the alveoli, which is called atelectasis
What is surfactant and what does it do?
A surface agent produced in the alveoli that decreases the surface tension of the fluid lining the alveoli, permitting expansion and preventing atelectasis
What is atelectasis and what is it often related to?
a collapse of some or all of the alveoli in the lungs. This is often related to a disease process or hypo-inflation of lung tissue
Gas exchange takes place across the ________-________ membrane
alveolar-capillary membrane
Describe the alveolar-capillary membrane and what it does.
Gas exachange takes place here. It is a thin membrane with an immense surface area that
promotes the alveolar ducts
diffusion of oxygen from the alveoli into the blood
diffusion of carbon dioxide out of the blood and into the alveoli to be exhaled.
Differentiate between respiration and ventilation.
respiration is the mechanical process of breathing-inhaling oxygen and exhaling carbon dioxide.
ventilation refers to the adequacy of respiratoin or breathing–the movement of air into and out of the lungs
Which brain areas are responsible for ventilation?
pons and medulla (brainstem)
Which will stimulate faster and deeper ventilation to a lesser degree?
a. decrease in pH in body fluids
b. decrease in blood oxygen concentration (hypoxemia)
c. increase in carbon dioxide in the blood
decrease in blood oxygen concentration (hypoxemia)
Which will lead to faster and deeper ventilation?
a. increase in pH in body’s fluids
b. decrease in pH in blody’s fluids
b. decrease in pH in blody’s fluids
How is inhalation of air initiated? (muscle)
the diaphragm contracts, pulling downward –increasing the size of the thoracic space
external muscles contract which elevate and separate the ribs and move the sternum forward
What is the effect of increasing space inside the thorax during inspiration?
decrease intrathoracic pressure, allowing the atmospheric air to fill the lungs
Explain what causes the cessation of inhalation
the stretch receptors in the lung tissue send signals back to the brain to cause it to stop, preventing over distension of the lungs
Explain how exhalation occurs
it occurs when the resp. muscles relax, thereby reducing the size of the intrathoracic space, increasing the intrathoracic pressure, and forcing air to exit the lungs
Under normal circumstances, exhalation is a ___________ process:
a. active
b. passive
b. passive
What may a patient have to do when the movement of air is impeded (muscular)
use additional muscles to increase the ventilatory effort
What muscles must a patient use when the movement of air is impeded?
accessory muscles:
sternocleidomastoid
abdominal
internal intercostals
When accessory muscles are required for breathing, the work of breathing is said to be:
a. passive
b. impaired
c. increased
d. active
e. decreased
c. increased
What is the exchange of oxygen from the alveoli into the pulmonary capillary blood called?
External respiration
What happens during external respiration?
oxygen diffuses across the alveolar membrane in response to a concentration gradient
- from higher concentration (alveoli) to lower (pulmonary capillary blood)
carbon dioxide difusses from the blood to the alveolar space, also in response to a concentration gradient
During alveolar gas exchange, oxygen and carbon dioxide diffuse across the alveolar-capillary membrane in response to what?
a concentration gradient
What happens to the oxygen molecules once the diffusion of oxygen across the alveolar-capillary membrane occurs?
oxygen is dissolved in the blood plasma
Three factors that influece the capacity of the blood to carry oxygen:
- the amount of dissolved oxygen in the plasma
- the hemoglobin level
- the tendency of the hemoglobin to bind with oxygen
What percentage of the total oxygen is carried in the plasma?
1% to 5%
The presence of what greately enhances the oxygen-carrying capacity of the blood?
the presence of hemoglobin in the RBCs (erythrocytes)
What are the two ways that the amount of oxygen carried in a sample of blood is measured?
- Partial pressure of oxygen (PaO2) = the oxygen dissolved in plasma
- the % of hemoglobin that is saturated with oxygen (SaO2) = the amount of oxygen bound to hemoglobin
What is PaO2?
The oxygen dissolved in the plasma is expressed as the partial pressure of oxygen.
What is the normal PaO2 in arterial blood?
The normal PaO2 in arterial blood is 80 - 100 mmHg
What is SaO2?
the % of hemoglobin that is saturated with oxygen.
What value reflects the hemoglobin being fully saturated?
100%
What is the normal saturation of arterial blood?
96-98%